ExPASy Proteomics Server

Accession	MF_01177
Dates	23-NOV-2006 (Created) 25-NOV-2009 (Last updated, Version 6)

Data class

Protein

Predictors

HAMAP; MF_01177; [distribution of match scores in UniProtKB];[seed alignment for MF_01177]

Names

HTH-type_NsrR

Identifier

NSRR

Protein name

RecName: Full=HTH-type transcriptional repressor nsrR;

Gene name

nsrR

FUNCTION: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity (By similarity).

COFACTOR: Binds 1 2Fe-2S cluster per subunit (Potential).

SIMILARITY: Contains 1 HTH rrf2-type DNA-binding domain.

PROSITE	PS01332; HTH_RRF2_1; 1; PS51197; HTH_RRF2_2; 1; trigger=PRU00540;
Pfam	PF02082; Rrf2; 1;
TIGRFAMs	TIGR00738; rrf2_super; 1;

2Fe-2S.

DNA-binding.

Iron, Iron-sulfur, Metal-binding.

Repressor, Transcription, Transcription regulation.

GO:0003690; Molecular function: double-stranded DNA binding.

GO:0005506; Molecular function: iron ion binding.

GO:0003700; Molecular function: transcription factor activity.
GO:0006355; Biological process: regulation of transcription, DNA-dependent.

From: NSRR_ECOLI (P0AF63)
Key		From		To		Description		Condition		FTGroup
METAL		91		91		Iron-sulfur (2Fe-2S) (Potential)		C		1
METAL		96		96		Iron-sulfur (2Fe-2S) (Potential)		C		1
METAL		102		102		Iron-sulfur (2Fe-2S) (Potential)		C		1

Size range:	141-144 amino acids
Related UniRules:	None
Template:	P0AF63 (NSRR_ECOLI)
Scope:	Bacteria; Gammaproteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None