ExPASy Proteomics Server

Accession	MF_01172
Dates	3-NOV-2006 (Created) 25-NOV-2009 (Last updated, Version 12)

Data class

Protein

Predictors

HAMAP; MF_01172; [distribution of match scores in UniProtKB];[seed alignment for MF_01172]

Names

AstB

Identifier

ASTB

Protein name

RecName: Full=N-succinylarginine dihydrolase; EC=3.5.3.23;

Gene name

astB

FUNCTION: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity).

CATALYTIC ACTIVITY: N(2)-succinyl-L-arginine + 2 H(2)O = N(2)-succinyl-L-ornithine + 2 NH(3) + CO(2).

PATHWAY: Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5.

SUBUNIT: Homodimer (By similarity).

SIMILARITY: Belongs to the succinylarginine dihydrolase family.

Pfam	PF04996; AstB; 1;

Arginine metabolism, Hydrolase.

GO:0009015; Molecular function: N-succinylarginine dihydrolase activity.
GO:0019544; Biological process: arginine catabolic process to glutamate.

From: ASTB_ECOLI (P76216)
Key		From		To		Description		Condition		FTGroup
REGION		19		28		Substrate binding (By similarity)
REGION		137		138		Substrate binding (By similarity)
ACT_SITE		174		174		By similarity		E
ACT_SITE		248		248		By similarity		H
ACT_SITE		365		365		Nucleophile (By similarity)		C
BINDING		110		110		Substrate (By similarity)		N
BINDING		212		212		Substrate (By similarity)		R
BINDING		250		250		Substrate (By similarity)		D
BINDING		359		359		Substrate (By similarity)		N

Size range:	415-449 amino acids
Related UniRules:	None
Template:	P76216 (ASTB_ECOLI)
Scope:	Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in CAUCR
Plasmid encoded:	None