ExPASy Proteomics Server

Accession	MF_01132
Dates	2-FEB-2004 (Created) 25-NOV-2009 (Last updated, Version 14)

Data class

Protein

Predictors

HAMAP; MF_01132; [distribution of match scores in UniProtKB];[seed alignment for MF_01132]

Names

SpxA

Identifier

SPX

Protein name

RecName: Full=Regulatory protein spx;

Gene name

spxA

FUNCTION: Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the arsC family. Spx subfamily.

Pfam	PF03960; ArsC; 1;
TIGRFAMs	TIGR01617; arsC_related; 1;

Cytoplasm.

Disulfide bond, Redox-active center.

Transcription, Transcription regulation.

GO:0030528; Molecular function: transcription regulator activity.
GO:0005737; Cellular component: cytoplasm.

From: SPX_BACSU (O31602)
Key		From		To		Description		Condition		FTGroup
DISULFID		10		13		Redox-active (Potential)		C-x-x-C

Size range:	128-137 amino acids
Related UniRules:	None
Template:	O31602 (SPX_BACSU)
Scope:	Bacteria; Firmicutes
Fusion:	Nter: None; Cter: None
Duplicate:	in BACAN, BACCR, LACLA, OCEIH
Plasmid encoded:	None