ExPASy Proteomics Server

Accession	MF_01108
Dates	27-MAR-2003 (Created) 25-NOV-2009 (Last updated, Version 27)

Data class

Protein

Predictors

HAMAP; MF_01108; [distribution of match scores in UniProtKB];[seed alignment for MF_01108]

Names

ArgE

Identifier

ARGE

Protein name

RecName: Full=Acetylornithine deacetylase; Short=Acetylornithinase; Short=AO; EC=3.5.1.16; AltName: Full=N-acetylornithinase; Short=NAO;

Gene name

argE

CATALYTIC ACTIVITY: N(2)-acetyl-L-ornithine + H(2)O = acetate + L-ornithine.

COFACTOR: Binds 2 zinc or cobalt ions per subunit (By similarity).

COFACTOR: Glutathione (By similarity).

PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine from N(2)-acetyl-L-ornithine (linear): step 1/1.

SUBUNIT: Homodimer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the peptidase M20A family. ArgE subfamily.

Pfam	PF01546; Peptidase_M20; 1;
PROSITE	PS00758; ARGE_DAPE_CPG2_1; 1; PS00759; ARGE_DAPE_CPG2_2; 1;

Cytoplasm, Amino-acid biosynthesis, Arginine biosynthesis, Hydrolase, Metal-binding, Cobalt, Zinc.

GO:0008777; Molecular function: acetylornithine deacetylase activity.
GO:0008270; Molecular function: zinc ion binding.
GO:0006526; Biological process: arginine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

From: ARGE_ECOLI (P23908)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		82		82		By similarity		D
ACT_SITE		144		144		By similarity		E
METAL		80		80		Cobalt or zinc 1 (By similarity)		H
METAL		112		112		Cobalt or zinc 1 (By similarity)		D
METAL		112		112		Cobalt or zinc 2 (By similarity)		D
METAL		145		145		Cobalt or zinc 2 (By similarity)		E
METAL		169		169		Cobalt or zinc 1 (By similarity)		E
METAL		355		355		Cobalt or zinc 2 (By similarity)		H

Size range:	378-389 amino acids
Related UniRules:	None
Template:	P23908 (ARGE_ECOLI)
Scope:	Bacteria; Enterobacteriaceae Bacteria; Vibrionales
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None