ExPASy Proteomics Server

Accession	MF_00664
Dates	28-JUN-2003 (Created) 25-NOV-2009 (Last updated, Version 17)

Data class

Protein

Predictors

HAMAP; MF_00664; [distribution of match scores in UniProtKB];[seed alignment for MF_00664]

Names

PS_decarb_type3

Identifier

PSD

Protein name

RecName: Full=Phosphatidylserine decarboxylase proenzyme; EC=4.1.1.65; RecName: Full=Phosphatidylserine decarboxylase alpha chain; RecName: Full=Phosphatidylserine decarboxylase beta chain;

Gene name

psd

CATALYTIC ACTIVITY: Phosphatidyl-L-serine = phosphatidylethanolamine + CO(2).

COFACTOR: Pyruvoyl group (By similarity).

PATHWAY: Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.

SIMILARITY: Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Pfam	PF02666; PS_Dcarbxylase; 1;
TIGRFAMs	TIGR00164; PS_decarb_rel; 1;

Phospholipid biosynthesis, Lyase, Decarboxylase, Pyruvate, Zymogen.

GO:0004609; Molecular function: phosphatidylserine decarboxylase activity.
GO:0008654; Biological process: phospholipid biosynthetic process.

From: PSD_AGRT5 (Q8UGH4)
Key		From		To		Description		Condition		FTGroup
CHAIN		Nter		189		Phosphatidylserine decarboxylase beta chain (By similarity)
CHAIN		190		Cter		Phosphatidylserine decarboxylase alpha chain (By similarity)
SITE		189		190		Cleavage (non-hydrolytic) (By similarity)		G-S
MOD_RES		190		190		Pyruvic acid (Ser) (By similarity)		S

Size range:	195-265 amino acids
Related UniRules:	MF_00662 (PSD); MF_00663 (PSD)
Template:	P0A8K1 (PSD_ECOLI)
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	in SILPO, SILST