ExPASy Proteomics Server

Accession	MF_00662
Dates	28-JUN-2003 (Created) 25-NOV-2009 (Last updated, Version 18)

Data class

Protein

Predictors

HAMAP; MF_00662; [distribution of match scores in UniProtKB];[seed alignment for MF_00662]

Names

PS_decarb_type1

Identifier

PSD

Protein name

RecName: Full=Phosphatidylserine decarboxylase proenzyme; EC=4.1.1.65; RecName: Full=Phosphatidylserine decarboxylase alpha chain; RecName: Full=Phosphatidylserine decarboxylase beta chain;

Gene name

psd

CATALYTIC ACTIVITY: Phosphatidyl-L-serine = phosphatidylethanolamine + CO(2).

COFACTOR: Pyruvoyl group (By similarity).

PATHWAY: Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.

SIMILARITY: Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Pfam	PF02666; PS_Dcarbxylase; 1;
TIGRFAMs	TIGR00163; PS_decarb; 1;

Phospholipid biosynthesis, Lyase, Decarboxylase, Pyruvate, Zymogen.

GO:0004609; Molecular function: phosphatidylserine decarboxylase activity.
GO:0008654; Biological process: phospholipid biosynthetic process.

From: PSD_BACSU (P39822)
Key		From		To		Description		Condition		FTGroup
CHAIN		Nter		229		Phosphatidylserine decarboxylase beta chain (By similarity)
CHAIN		230		Cter		Phosphatidylserine decarboxylase alpha chain (By similarity)
SITE		229		230		Cleavage (non-hydrolytic) (By similarity)		G-S
MOD_RES		230		230		Pyruvic acid (Ser) (By similarity)		S

Size range:	259-341 amino acids
Related UniRules:	MF_00663 (PSD); MF_00664 (PSD)
Template:	P0A8K1 (PSD_ECOLI)
Scope:	Bacteria
Fusion:	Nter: <Unknown>, <Rhodanese domains>; Cter: None
Duplicate:	None
Plasmid encoded:	None