ExPASy Proteomics Server

Accession	MF_00654
Dates	13-JUN-2003 (Created) 25-NOV-2009 (Last updated, Version 20)

Data class

Protein

Predictors

HAMAP; MF_00654; [distribution of match scores in UniProtKB];[seed alignment for MF_00654]

Names

PQQ_syn_PqqC

Identifier

PQQC

Protein name

RecName: Full=Pyrroloquinoline-quinone synthase; EC=1.3.3.11; AltName: Full=Coenzyme PQQ synthesis protein C; AltName: Full=Pyrroloquinoline quinone biosynthesis protein C;

Gene name

pqqC

FUNCTION: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ (By similarity).

CATALYTIC ACTIVITY: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H(2)O(2) + 2 H(2)O.

PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.

SIMILARITY: Belongs to the pqqC family.

Pfam	PF03070; TENA_THI-4; 1;
TIGRFAMs	TIGR02111; PQQ_syn_pqqC; 1;

Oxidoreductase, PQQ biosynthesis.

GO:0018189; Biological process: pyrroloquinoline quinone biosynthetic process.

Size range:	239-268 amino acids
Related UniRules:	None
Template:	P27505 (PQQC_KLEPN)
Scope:	Bacteria
Fusion:	Nter: None; Cter: MF_00655 (pqqD)
Duplicate:	None
Plasmid encoded:	in RHIME