ExPASy Proteomics Server

Accession	MF_00647
Dates	4-JUN-2003 (Created) 25-NOV-2009 (Last updated, Version 18)

Data class

Protein

Predictors

HAMAP; MF_00647; [distribution of match scores in UniProtKB];[seed alignment for MF_00647]

Names

PPAT_arch

Identifier

COAD

Protein name

RecName: Full=Phosphopantetheine adenylyltransferase; EC=2.7.7.3; AltName: Full=Pantetheine-phosphate adenylyltransferase; Short=PPAT; AltName: Full=Dephospho-CoA pyrophosphorylase;

Gene name

coaD

FUNCTION: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).

CATALYTIC ACTIVITY: ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA.

PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the eukaryotic coaD family.

Pfam	PF01467; CTP_transf_2; 1;
TIGRFAMs	TIGR00125; cyt_tran_rel; 1;

ATP-binding, Coenzyme A biosynthesis, Cytoplasm, Nucleotide-binding, Nucleotidyltransferase, Transferase.

GO:0004595; Molecular function: pantetheine-phosphate adenylyltransferase activity.
GO:0015937; Biological process: coenzyme A biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Size range:	147-165 amino acids
Related UniRules:	None
Template:	Q9UYT0 (COAD_PYRAB)
Scope:	Archaea
Fusion:	Nter: None; Cter: MF_00648 (Ynnn)
Duplicate:	None
Plasmid encoded:	None