ExPASy Proteomics Server

Accession	MF_00628
Dates	24-MAR-2003 (Created) 25-NOV-2009 (Last updated, Version 15)

Data class

Protein

Predictors

HAMAP; MF_00628; [distribution of match scores in UniProtKB];[seed alignment for MF_00628]

Names

Pept_tRNA_hydro_arch

Identifier

PTH

Protein name

RecName: Full=Peptidyl-tRNA hydrolase; Short=PTH; EC=3.1.1.29;

Gene name

pth

FUNCTION: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis (By similarity).

CATALYTIC ACTIVITY: N-substituted aminoacyl-tRNA + H(2)O = N-substituted amino acid + tRNA.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the PTH2 family.

Pfam	PF01981; PTH2; 1;
TIGRFAMs	TIGR00283; Pep_tRNA_hydro_PTH2; 1;

Cytoplasm, Hydrolase.

GO:0004045; Molecular function: aminoacyl-tRNA hydrolase activity.
GO:0006412; Biological process: translation.
GO:0005737; Cellular component: cytoplasm.

Size range:	112-124 amino acids
Related UniRules:	None
Template:	Q60363 (PTH_METJA); Q980V1 (PTH_SULSO): [Recover all]
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None