ExPASy Proteomics Server

Accession	MF_00626
Dates	20-MAR-2003 (Created) 25-NOV-2009 (Last updated, Version 12)

Data class

Protein

Predictors

HAMAP; MF_00626; [distribution of match scores in UniProtKB];[seed alignment for MF_00626]

Names

Germination_prot

Identifier

GPR

Protein name

RecName: Full=Germination protease; EC=3.4.24.78; AltName: Full=Spore protease; AltName: Full=GPR endopeptidase; AltName: Full=Germination proteinase; Flags: Precursor;

Gene name

gpr

FUNCTION: Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity).

CATALYTIC ACTIVITY: Endopeptidase action with P4 Glu or Asp, P1 preferably Glu > Asp, P1' hydrophobic and P2' Ala.

SUBUNIT: Homotetramer (By similarity).

PTM: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination (By similarity).

SIMILARITY: Belongs to the peptidase A25 family.

Pfam	PF03418; Peptidase_A25; 1;
PIRSF	PIRSF019549; Peptidase_A25; 1;
TIGRFAMs	TIGR01441; GPR; 1;

Hydrolase, Protease, Zymogen.

GO:0004222; Molecular function: metalloendopeptidase activity.
GO:0006508; Biological process: proteolysis.
GO:0009847; Biological process: spore germination.

From: GPR_BACME (P22321)
Key		From		To		Description		Condition		FTGroup
PROPEP		Nter		15		By similarity
CHAIN		16		Cter		Germination protease

Size range:	323-372 amino acids
Related UniRules:	None
Template:	P22321 (GPR_BACME)
Scope:	Bacteria; Bacillales Bacteria; Clostridia
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None