ExPASy Proteomics Server

Accession	MF_00526
Dates	16-JAN-2002 (Created) 25-NOV-2009 (Last updated, Version 21)

Data class

Protein

Predictors

HAMAP; MF_00526; [distribution of match scores in UniProtKB];[seed alignment for MF_00526]

Names

MthylAspMutase_S

Identifier

MAMA

Protein name

RecName: Full=Methylaspartate mutase S chain; EC=5.4.99.1; AltName: Full=Glutamate mutase subunit sigma;

Gene name

mamA

CATALYTIC ACTIVITY: L-threo-3-methylaspartate = L-glutamate.

COFACTOR: 5'-deoxy-5'-adenosyl-adeninylcobamide (pseudo-coenzyme B12) (By similarity).

PATHWAY: Amino-acid degradation; L-glutamate degradation via mesaconate pathway; acetate and pyruvate from L-glutamate: step 1/4.

SUBUNIT: Heterotetramer of 2 E subunits and 2 S subunits (By similarity).

SIMILARITY: Contains 1 B12-binding domain.

Pfam	PF02310; B12-binding; 1;
PROSITE	PS51332; B12_BINDING; 1;

Isomerase, Cobalt, Cobalamin, Metal-binding.

GO:0050097; Molecular function: methylaspartate mutase activity.
GO:0019670; Biological process: anaerobic glutamate catabolic process.

From: MAMA_CLOCO (P80078)
Key		From		To		Description		Condition		FTGroup
METAL		16		16		Cobalt (cobalamin axial ligand) (By similarity)		H

Size range:	136-151 amino acids
Related UniRules:	None
Template:	P80078 (MAMA_CLOCO); Q05488 (MAMA_CLOTT): [Recover all]
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	in HALMA
Plasmid encoded:	None
Comments:	The B-12 binding domain boundaries come from Pfam.