ExPASy Proteomics Server

Accession	MF_00453
Dates	25-SEP-2001 (Created) 25-NOV-2009 (Last updated, Version 22)

Data class

Protein

Predictors

HAMAP; MF_00453; [distribution of match scores in UniProtKB];[seed alignment for MF_00453]

Names

PEPCK_ATP

Identifier

PCKA

Protein name

RecName: Full=Phosphoenolpyruvate carboxykinase [ATP]; Short=PEP carboxykinase; Short=PEPCK; EC=4.1.1.49; AltName: Full=Phosphoenolpyruvate carboxylase;

Gene name

pckA

CATALYTIC ACTIVITY: ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO(2).

PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase [ATP] family.

Pfam	PF01293; PEPCK_ATP; 1;
TIGRFAMs	TIGR00224; pckA; 1;
PROSITE	PS00532; PEPCK_ATP; 1;

Acetylation.

Cytoplasm, Gluconeogenesis, Lyase, Decarboxylase, ATP-binding, Nucleotide-binding.

GO:0005524; Molecular function: ATP binding.
GO:0004612; Molecular function: phosphoenolpyruvate carboxykinase (ATP) activity.
GO:0006094; Biological process: gluconeogenesis.
GO:0005737; Cellular component: cytoplasm.

From: PCKA_ECOLI (P22259)
Key		From		To		Description		Condition		FTGroup
NP_BIND		248		255		ATP (By similarity)		G-L-S-G-T-G-K-T

Key		From		To		Description		Condition		FTGroup
MOD_RES		87		87		N6-acetyllysine (By similarity)		K
MOD_RES		523		523		N6-acetyllysine (By similarity)		K

Size range:	493-542 amino acids
Related UniRules:	None
Template:	P22259 (PCKA_ECOLI); P41033 (PCKA_SALTY): [Recover all]
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	in MOOTA, SALRD
Plasmid encoded:	None
Comments:	Probable C-terminally frameshifted DEIRA not taken into alignment and size range