ExPASy Proteomics Server

Accession	MF_00370
Dates	1-JUN-2001 (Created) 25-NOV-2009 (Last updated, Version 26)

Data class

Protein

Predictors

HAMAP; MF_00370; [distribution of match scores in UniProtKB];[seed alignment for MF_00370]

Names

Shik_kinase_arch

Identifier

AROK

Protein name

RecName: Full=Shikimate kinase; Short=SK; EC=2.7.1.71;

Gene name

aroK

CATALYTIC ACTIVITY: ATP + shikimate = ADP + shikimate 3-phosphate.

PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.

Pfam	PF08544; GHMP_kinases_C; 1; PF00288; GHMP_kinases_N; 1;
PIRSF	PIRSF005758; Shikimt_kin_arch; 1;
TIGRFAMs	TIGR01920; Shik_kin_archae; 1;
PROSITE	PS00627; GHMP_KINASES_ATP; 1;

Cytoplasm, Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Transferase, Kinase, ATP-binding, Nucleotide-binding.

GO:0005524; Molecular function: ATP binding.
GO:0004765; Molecular function: shikimate kinase activity.
GO:0009073; Biological process: aromatic amino acid family biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

From: AROK_METJA (Q58835)
Key		From		To		Description		Condition		FTGroup
NP_BIND		86		96		ATP (Potential)		P-x(3)-G-L-x-[GS]-S-[SA]-A

Size range:	268-294 amino acids
Related UniRules:	None
Template:	Q58835 (AROK_METJA)
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	Bacterial aroK belong to a separate family