ExPASy Proteomics Server

Accession	MF_00336
Dates	1-JUN-2001 (Created) 5-FEB-2010 (Last updated, Version 26)

Data class

Protein

Predictors

HAMAP; MF_00336; [distribution of match scores in UniProtKB];[seed alignment for MF_00336]

Names

BioD

Identifier

BIOD

Protein name

RecName: Full=Dethiobiotin synthetase; EC=6.3.3.3; AltName: Full=Dethiobiotin synthase; AltName: Full=DTB synthetase; Short=DTBS;

Gene name

bioD

CATALYTIC ACTIVITY: ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin.

COFACTOR: Magnesium (By similarity).

PATHWAY: Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.

SIMILARITY: Belongs to the dethiobiotin synthetase family.

Pfam	PF01656; CbiA; 1;
TIGRFAMs	TIGR00347; bioD; 1;

Biotin biosynthesis, Ligase, Magnesium, ATP-binding, Nucleotide-binding.

GO:0005524; Molecular function: ATP binding.
GO:0004141; Molecular function: dethiobiotin synthase activity.
GO:0000287; Molecular function: magnesium ion binding.
GO:0009102; Biological process: biotin biosynthetic process.

From: BIOD_ECOLI (P13000)
Key		From		To		Description		Condition		FTGroup
NP_BIND		9		17		ATP (By similarity)		[GA]-x-x-T-x-x-G-K-[ST]

Size range:	191-256 amino acids
Related UniRules:	None
Template:	P13000 (BIOD_ECOLI); P22818 (BIOD_BACSH): [Recover all]
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	in ECO57, ECOLI, HAEIN, PASMU, SALTI, SALTY, YERPE
Plasmid encoded:	None