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HAMAP annotation rule: MF_00297

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General rule information

Accession MF_00297
Dates 1-JUN-2001 (Created)
25-NOV-2009 (Last updated, Version 19)
Data class Protein
Predictors HAMAP; MF_00297; [distribution of match scores in UniProtKB];[seed alignment for MF_00297]
Names Nudix_NudC


Propagated annotation

Identifier, protein and gene names
Identifier NUDC
Protein name
RecName: Full=NADH pyrophosphatase;
EC=3.6.1.22;
Gene name nudC
Comments
CATALYTIC ACTIVITY: NAD(+) + H(2)O = AMP + NMN.
COFACTOR: Divalent ions. Manganese or magnesium (By similarity).
SUBUNIT: Homodimer (By similarity).
SIMILARITY: Belongs to the Nudix hydrolase family. NudC subfamily.
Cross-references
Pfam PF00293; NUDIX; 1;
PF09296; NUDIX-like; 1;
PF09297; zf-NADH-PPase; 1;
PRINTS PR00502; NUDIXFAMILY; 1;
PROSITE PS51462; NUDIX; 1; trigger=PRU00794;
PS00893; NUDIX_BOX; 1;
Keywords
Hydrolase, NAD, Magnesium, Manganese.
Gene Ontology
GO:0000210; Molecular function: NAD+ diphosphatase activity.
GO:0000287; Molecular function: magnesium ion binding.
GO:0030145; Molecular function: manganese ion binding.
Features
From: NUDC_ECOLI (P32664)
Key     From     To       Description   Condition   FTGroup
MOTIF     159     180       Nudix box      


Additional information

Size range: 257-313 amino acids
Related UniRules: None
Template: P32664 (NUDC_ECOLI)
Scope: Bacteria
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None
Comments: Possible wrong start in MYCTU

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UniProtKB rule member sequences