ExPASy Proteomics Server

Accession	MF_00254
Dates	1-JUN-2001 (Created) 25-NOV-2009 (Last updated, Version 20)

Data class

Protein

Predictors

HAMAP; MF_00254; [distribution of match scores in UniProtKB];[seed alignment for MF_00254]

Names

Gly_tRNA_synth_alpha

Identifier

SYGA

Protein name

RecName: Full=Glycyl-tRNA synthetase alpha subunit; EC=6.1.1.14; AltName: Full=Glycine--tRNA ligase alpha subunit; Short=GlyRS;

Gene name

glyQ

CATALYTIC ACTIVITY: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).

SUBUNIT: Tetramer of two alpha and two beta subunits (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.

Pfam	PF02091; tRNA-synt_2e; 1;
PRINTS	PR01044; TRNASYNTHGA; 1;
TIGRFAMs	TIGR00388; glyQ; 1;
PROSITE	PS50861; AA_TRNA_LIGASE_II_GLYAB; 1;

Cytoplasm, Aminoacyl-tRNA synthetase, Protein biosynthesis, Ligase, ATP-binding, Nucleotide-binding.

GO:0005524; Molecular function: ATP binding.
GO:0004820; Molecular function: glycine-tRNA ligase activity.
GO:0006426; Biological process: glycyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.

Size range:	285-319 amino acids
Related UniRules:	None
Template:	O23627 (SYGM1_ARATH)
Scope:	Bacteria
Fusion:	Nter: None; Cter: MF_00255 (glyS)
Duplicate:	None
Plasmid encoded:	None
Comments:	glyQ and glyS are fused in Chlamydia. Possible wrong start in XYLFA.