ExPASy Proteomics Server

Accession	MF_00126
Dates	1-JUN-2001 (Created) 25-NOV-2009 (Last updated, Version 21)

Data class

Protein

Predictors

HAMAP; MF_00126; [distribution of match scores in UniProtKB];[seed alignment for MF_00126]

Names

Gln_tRNA_synth

Identifier

SYQ

Protein name

RecName: Full=Glutaminyl-tRNA synthetase; EC=6.1.1.18; AltName: Full=Glutamine--tRNA ligase; Short=GlnRS;

Gene name

glnS

CATALYTIC ACTIVITY: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).

SUBUNIT: Monomer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.

Pfam	PF00749; tRNA-synt_1c; 1;
PRINTS	PR00987; TRNASYNTHGLU; 1;
TIGRFAMs	TIGR00440; glnS; 1;
PROSITE	PS00178; AA_TRNA_LIGASE_I; 1;

Cytoplasm, Aminoacyl-tRNA synthetase, Protein biosynthesis, Ligase, ATP-binding, Nucleotide-binding.

GO:0005524; Molecular function: ATP binding.
GO:0004819; Molecular function: glutamine-tRNA ligase activity.
GO:0006424; Biological process: glutamyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.

From: SYQ_ECOLI (P00962)
Key		From		To		Description		Condition		FTGroup
MOTIF		34		44		"HIGH" region		P-[ED]-P-[NS]-G-[YF]-x-H-[LI]-G-H
MOTIF		268		272		"KMSKS" region		[LVI]-[LMT]-S-K-R
BINDING		271		271		ATP (By similarity)		K

Size range:	552-636 amino acids
Related UniRules:	None
Template:	P00962 (SYQ_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: MF_00121 (gatB)
Duplicate:	None
Plasmid encoded:	None
Comments:	Partial gatB like C-terminal domain in DEIRA. Possible wrong start site in DEIRA.