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| HAMAP annotation rule: MF_00115 |
| Accession | MF_00115 |
| Dates | 1-JUN-2001 (Created) 25-NOV-2009 (Last updated, Version 33) |
| Data class | Protein |
| Predictors | HAMAP; MF_00115; [distribution of match scores in UniProtKB];[seed alignment for MF_00115] |
| Names | MscL |
| Identifier | MSCL |
| Protein name |
|
| Gene name | mscL |
FUNCTION: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity).
SUBUNIT: Homopentamer (By similarity).
case <Property:Membrane=1>
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).
else case <Property:Membrane=2>
SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).
end case
SIMILARITY: Belongs to the mscL family.
| Pfam |
PF01741; MscL; 1; |
| TIGRFAMs |
TIGR00220; mscL; 1; |
| PROSITE |
PS01327; MSCL; 1; |
| General |
Transmembrane; -; 2-3; trigger=Yes; |
case <Property:Membrane=2>
end case
GO:0015267; Molecular function: channel activity.
GO:0006810; Biological process: transport.
GO:0005886; Cellular component: plasma membrane.
GO:0006810; Biological process: transport.
GO:0005886; Cellular component: plasma membrane.
| Size range: | 116-161 amino acids |
| Related UniRules: | None |
| Template: | P0A742 (MSCL_ECOLI); P0A5K8 (MSCL_MYCTU): [Recover all] |
| Scope: | Bacteria |
| Fusion: | Nter: None; Cter: None |
| Duplicate: | in RHILO |
| Plasmid encoded: | None |
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