ExPASy Proteomics Server

Accession	MF_00110
Dates	1-JUN-2001 (Created) 25-NOV-2009 (Last updated, Version 32)

Data class

Protein

Predictors

HAMAP; MF_00110; [distribution of match scores in UniProtKB];[seed alignment for MF_00110]

Names

DHQ_synthase

Identifier

AROB

Protein name

RecName: Full=3-dehydroquinate synthase; EC=4.2.3.4;

Gene name

aroB

CATALYTIC ACTIVITY: 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate.

COFACTOR: Divalent metal cations (By similarity).

COFACTOR: NAD (By similarity).

PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.

SUBUNIT: Monomer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the dehydroquinate synthase family.

Pfam	PF01761; DHQ_synthase; 1;

Cytoplasm, Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Lyase, NAD.

GO:0003856; Molecular function: 3-dehydroquinate synthase activity.
GO:0009073; Biological process: aromatic amino acid family biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Size range:	331-394 amino acids
Related UniRules:	None
Template:	P07639 (AROB_ECOLI)
Scope:	Bacteria Archaea
Fusion:	Nter: MF_00109 (aroK); Cter: <gppA / PPX>
Duplicate:	None
Plasmid encoded:	None
Comments:	Possible wrong start in CHLPN