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         UniProtKB/Swiss-Prot protein knowledgebase release 55.6 statistics


1.  INTRODUCTION

Release 55.6 of 01-Jul-08 of UniProtKB/Swiss-Prot contains 390696 sequence entries,
comprising 140503634 amino acids abstracted from 171250 references. 

1671 sequences have been added since release 55.5, the sequence data of
70 existing entries has been updated and the annotations of
24738 entries have been revised.

Number of fragments: 8132
Number of additional sequences produced by alternative splicing, initiation or promoter usage, or ribosomal frameshifting: 26036


Protein existence:
PE 1: Evidence at protein level    59554 entries
PE 2: Evidence at transcript level 62868 entries
PE 3: Inferred from homology       254004 entries
PE 4: Predicted                    13076 entries
PE 5: Uncertain                    1194 entries


The growth of the database is summarized below.

   



2.  AMINO ACID COMPOSITION

   2.1  Composition in percent for the complete database

   Ala (A) 8.13   Gln (Q) 3.95   Leu (L) 9.67   Ser (S) 6.66
   Arg (R) 5.49   Glu (E) 6.73   Lys (K) 5.88   Thr (T) 5.36
   Asn (N) 4.05   Gly (G) 7.04   Met (M) 2.41   Trp (W) 1.09
   Asp (D) 5.40   His (H) 2.28   Phe (F) 3.88   Tyr (Y) 2.93
   Cys (C) 1.42   Ile (I) 5.92   Pro (P) 4.78   Val (V) 6.82

   Asx (B) 0.000  Glx (Z) 0.000  Xaa (X) 0.00

   

   Legend: gray = aliphatic, red = acidic, green = small hydroxy,
           blue = basic, black = aromatic, white = amide, yellow = sulfur


   2.2  Classification of the amino acids by their frequency

   Leu, Ala, Gly, Val, Glu, Ser, Ile, Lys, Arg, Asp, Thr, Pro, Asn, Gln,
   Phe, Tyr, Met, His, Cys, Trp


3.  TAXONOMIC ORIGIN

   Total number of species represented in this release of UniProtKB/Swiss-Prot: 11444

   The first twenty species represent 97825 sequences:    25 % of the total
   number of entries.


   3.1 Table of the frequency of occurrence of species

        Species represented 1x: 5234
                            2x: 1698
                            3x:  823
                            4x:  545
                            5x:  418
                            6x:  318
                            7x:  231
                            8x:  195
                            9x:  168
                           10x:  107
                       11- 20x:  511
                       21- 50x:  344
                       51-100x:  140
                         >100x:  712


   3.2  Table of the most represented species

  ------  ---------  --------------------------------------------
  Number  Frequency  Species
  ------  ---------  --------------------------------------------
       1      19929  Homo sapiens (Human)
       2      15740  Mus musculus (Mouse)
       3       7098  Rattus norvegicus (Rat)
       4       6867  Arabidopsis thaliana (Mouse-ear cress)
       5       6554  Saccharomyces cerevisiae (Baker's yeast)
       6       5327  Bos taurus (Bovine)
       7       4421  Schizosaccharomyces pombe (Fission yeast)
       8       4343  Escherichia coli (strain K12)
       9       3189  Caenorhabditis elegans
      10       2876  Bacillus subtilis
      11       2813  Drosophila melanogaster (Fruit fly)
      12       2788  Xenopus laevis (African clawed frog)
      13       2344  Dictyostelium discoideum (Slime mold)
      14       2162  Danio rerio (Zebrafish) (Brachydanio rerio)
      15       2111  Pongo abelii (Sumatran orangutan)
      16       2045  Gallus gallus (Chicken)
      17       1947  Escherichia coli O157:H7
      18       1782  Methanocaldococcus jannaschii (Methanococcus jannaschii)
      19       1774  Haemophilus influenzae
      20       1715  Oryza sativa subsp. japonica (Rice)
      21       1698  Salmonella typhimurium
      22       1624  Escherichia coli O6
      23       1623  Shigella flexneri
      24       1442  Mycobacterium tuberculosis
      25       1318  Sus scrofa (Pig)
      26       1290  Salmonella typhi
      27       1240  Pseudomonas aeruginosa
      28       1183  Mycobacterium bovis
      29       1169  Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
      30       1117  Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
      31        988  Synechocystis sp. (strain PCC 6803)
      32        980  Archaeoglobus fulgidus
      33        950  Yersinia pestis
      34        912  Vibrio cholerae
      35        909  Acanthamoeba polyphaga mimivirus (APMV)
      36        886  Rhizobium meliloti (Sinorhizobium meliloti)
      37        871  Oryctolagus cuniculus (Rabbit)
      38        861  Salmonella paratyphi A
      39        859  Staphylococcus aureus (strain Mu50 / ATCC 700699)
      40        858  Staphylococcus aureus (strain N315)
      41        830  Staphylococcus aureus (strain MW2)
      42        830  Staphylococcus aureus (strain COL)
      43        826  Staphylococcus aureus (strain MSSA476)
      44        823  Staphylococcus aureus (strain MRSA252)
      45        809  Salmonella choleraesuis
      46        807  Yersinia pseudotuberculosis
      47        806  Shigella sonnei (strain Ss046)
      48        802  Escherichia coli O6:K15:H31 (strain 536 / UPEC)
      49        763  Vibrio parahaemolyticus
      50        763  Ashbya gossypii (Yeast) (Eremothecium gossypii)
      51        762  Shigella boydii serotype 4 (strain Sb227)
      52        759  Aquifex aeolicus
      53        754  Pasteurella multocida
      54        746  Shigella dysenteriae serotype 1 (strain Sd197)
      55        745  Canis familiaris (Dog)
      56        741  Escherichia coli O9:H4 (strain HS)
      57        738  Escherichia coli (strain UTI89 / UPEC)
      58        737  Escherichia coli O139:H28 (strain E24377A / ETEC)
      59        736  Kluyveromyces lactis (Yeast) (Candida sphaerica)
      60        727  Candida albicans (Yeast)
      61        722  Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum)
      62        717  Neurospora crassa
      63        707  Streptomyces coelicolor
      64        705  Vibrio vulnificus
      65        705  Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)
      66        699  Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
      67        698  Staphylococcus epidermidis (strain ATCC 12228)
      68        694  Candida glabrata (Yeast) (Torulopsis glabrata)
      69        691  Photorhabdus luminescens subsp. laumondii
      70        688  Vibrio vulnificus (strain YJ016)
      71        688  Bacillus halodurans
      72        687  Mycoplasma pneumoniae
      73        681  Shigella flexneri serotype 5b (strain 8401)
      74        668  Pan troglodytes (Chimpanzee)
      75        663  Bacillus anthracis
      76        653  Yersinia pestis bv. Antiqua (strain Nepal516)
      77        651  Anabaena sp. (strain PCC 7120)
      78        647  Yersinia pestis bv. Antiqua (strain Antiqua)
      79        647  Mycobacterium leprae
      80        647  Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)
      81        637  Pseudomonas syringae pv. tomato
      82        636  Pseudomonas putida (strain KT2440)
      83        634  Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
      84        626  Escherichia coli O1:K1 / APEC
      85        619  Escherichia coli
      86        619  Staphylococcus aureus (strain NCTC 8325)
      87        616  Bradyrhizobium japonicum
      88        615  Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
      89        613  Treponema pallidum
      90        609  Zea mays (Maize)
      91        607  Enterobacter sp. (strain 638)
      92        596  Yersinia pestis (strain Pestoides F)
      93        595  Methanobacterium thermoautotrophicum
      94        594  Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
      95        590  Bacillus cereus (strain ATCC 14579 / DSM 31)
      96        590  Agrobacterium tumefaciens (strain C58 / ATCC 33970)
      97        585  Ralstonia solanacearum (Pseudomonas solanacearum)
      98        583  Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
      99        581  Shewanella oneidensis
     100        581  Rickettsia prowazekii
     101        579  Helicobacter pylori (Campylobacter pylori)
     102        576  Rhizobium loti (Mesorhizobium loti)
     103        574  Staphylococcus aureus (strain USA300)
     104        573  Serratia proteamaculans (strain 568)
     105        572  Buchnera aphidicola subsp. Acyrthosiphon pisum 
     106        568  Listeria monocytogenes
     107        566  Lactococcus lactis subsp. lactis (Streptococcus lactis)
     108        562  Buchnera aphidicola subsp. Schizaphis graminum
     109        562  Staphylococcus aureus (strain bovine RF122)
     110        560  Photobacterium profundum (Photobacterium sp. (strain SS9))
     111        560  Helicobacter pylori J99 (Campylobacter pylori J99)
     112        560  Listeria innocua
     113        558  Neisseria meningitidis serogroup B
     114        556  Xanthomonas campestris pv. campestris
     115        551  Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
     116        545  Staphylococcus haemolyticus (strain JCSC1435)
     117        539  Staphylococcus saprophyticus subsp. saprophyticus 
     118        538  Neisseria meningitidis serogroup A
     119        536  Brucella melitensis
     120        533  Brucella suis
     121        532  Bacillus cereus (strain ATCC 10987)
     122        532  Yarrowia lipolytica (Candida lipolytica)
     123        531  Clostridium acetobutylicum
     124        528  Caulobacter crescentus (Caulobacter vibrioides)
     125        524  Enterobacter sakazakii (strain ATCC BAA-894)
     126        521  Emericella nidulans (Aspergillus nidulans)
     127        521  Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
     128        521  Xanthomonas axonopodis pv. citri
     129        514  Oceanobacillus iheyensis
     130        512  Bacillus thuringiensis subsp. konkukian
     131        509  Pseudomonas syringae pv. syringae (strain B728a)
     132        507  Buchnera aphidicola subsp. Baizongia pistaciae
     133        507  Streptococcus pneumoniae
     134        503  Vibrio fischeri (strain ATCC 700601 / ES114)
     135        503  Pseudomonas fluorescens (strain PfO-1)
     136        501  Listeria monocytogenes serotype 4b (strain F2365)
     137        500  Bacillus cereus (strain ZK / E33L)
     138        499  Xylella fastidiosa
     139        498  Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
     140        498  Pseudomonas aeruginosa (strain UCBPP-PA14)
     141        496  Thermotoga maritima
     142        491  Bacillus licheniformis (strain DSM 13 / ATCC 14580)
     143        491  Rickettsia conorii
     144        491  Bordetella bronchiseptica (Alcaligenes bronchisepticus)
     145        490  Xylella fastidiosa (strain Temecula1 / ATCC 700964)
     146        488  Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
     147        483  Mycoplasma genitalium
     148        481  Haemophilus ducreyi
     149        480  Bordetella parapertussis
     150        480  Chromobacterium violaceum
     151        480  Bordetella pertussis
     152        478  Deinococcus radiodurans
     153        473  Clostridium perfringens
     154        472  Sodalis glossinidius (strain morsitans)
     155        469  Corynebacterium glutamicum (Brevibacterium flavum)
     156        465  Vibrio cholerae serotype O1 (strain ATCC 39541 / Ogawa 395 / O395)
     157        464  Methanosarcina acetivorans
     158        459  Brucella abortus
     159        457  Haemophilus influenzae (strain 86-028NP)
     160        456  Pyrococcus horikoshii
     161        455  Mannheimia succiniciproducens (strain MBEL55E)
     162        454  Pseudomonas entomophila (strain L48)
     163        452  Pyrococcus abyssi
     164        452  Streptomyces avermitilis
     165        451  Xanthomonas campestris pv. campestris (strain 8004)
     166        448  Halobacterium salinarium (Halobacterium halobium)
     167        446  Rickettsia felis (Rickettsia azadi)
     168        446  Enterococcus faecalis (Streptococcus faecalis)
     169        445  Pseudomonas aeruginosa (strain PA7)
     170        444  Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
     171        444  Methanosarcina mazei (Methanosarcina frisia)
     172        444  Bacillus clausii (strain KSM-K16)
     173        442  Burkholderia pseudomallei (Pseudomonas pseudomallei)
     174        442  Shewanella sp. (strain MR-7)
     175        439  Lactobacillus plantarum
     176        439  Shewanella sp. (strain MR-4)
     177        438  Synechococcus elongatus (Thermosynechococcus elongatus)
     178        438  Vibrio harveyi (strain ATCC BAA-1116 / BB120)
     179        438  Geobacillus kaustophilus
     180        436  Streptococcus mutans
     181        436  Chlamydia trachomatis
     182        434  Thermoanaerobacter tengcongensis
     183        434  Oryza sativa subsp. indica (Rice)
     184        433  Rickettsia bellii (strain RML369-C)
     185        433  Pyrococcus furiosus
     186        431  Ovis aries (Sheep)
     187        429  Streptococcus pyogenes serotype M6
     188        429  Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2)
     189        428  Acinetobacter sp. (strain ADP1)
     190        428  Brucella abortus (strain 2308)
     191        427  Borrelia burgdorferi (Lyme disease spirochete)
     192        427  Nicotiana tabacum (Common tobacco)
     193        425  Rhodopseudomonas palustris
     194        422  Burkholderia sp. (strain 383) (Burkholderia cepacia 
     195        422  Campylobacter jejuni
     196        422  Anabaena variabilis (strain ATCC 29413 / PCC 7937)
     197        421  Xanthomonas campestris pv. vesicatoria (strain 85-10)
     198        420  Burkholderia mallei (Pseudomonas mallei)
     199        419  Chlamydia pneumoniae (Chlamydophila pneumoniae)
     200        418  Pseudomonas putida (strain F1 / ATCC 700007)
     201        414  Shewanella frigidimarina (strain NCIMB 400)
     202        414  Aspergillus fumigatus (Sartorya fumigata)
     203        413  Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus)
     204        413  Shewanella sp. (strain ANA-3)
     205        412  Xanthomonas oryzae pv. oryzae (strain MAFF 311018)
     206        411  Pseudomonas putida (strain GB-1)
     207        410  Methylococcus capsulatus
     208        409  Chlamydia muridarum
     209        409  Streptococcus pyogenes serotype M1
     210        408  Rhizobium sp. (strain NGR234)
     211        407  Ralstonia eutropha  (Cupriavidus necator 
     212        407  Sulfolobus solfataricus
     213        406  Staphylococcus aureus (strain Newman)
     214        405  Streptococcus pyogenes serotype M18
     215        403  Rickettsia typhi
     216        403  Streptococcus pyogenes serotype M3
     217        402  Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
     218        400  Nitrosomonas europaea
     219        399  Bacillus amyloliquefaciens (strain FZB42)
     220        398  Shewanella baltica (strain OS185)
     221        397  Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
     222        396  Hahella chejuensis (strain KCTC 2396)
     223        396  Gloeobacter violaceus
     224        395  Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240)
     225        394  Pseudoalteromonas haloplanktis (strain TAC 125)
     226        392  Corynebacterium efficiens
     227        391  Dechloromonas aromatica (strain RCB)
     228        390  Staphylococcus aureus (strain Mu3 / ATCC 700698)
     229        389  Chlorobium tepidum
     230        389  Shewanella sp. (strain W3-18-1)
     231        389  Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
     232        388  Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)
     233        387  Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
     234        385  Burkholderia xenovorans (strain LB400)
     235        384  Mycobacterium paratuberculosis
     236        384  Idiomarina loihiensis
     237        384  Pseudomonas mendocina (strain ymp)
     238        383  Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) 
     239        381  Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
     240        381  Synechococcus sp. (strain WH8102)
     241        381  Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
     242        380  Haemophilus influenzae (strain PittEE)
     243        380  Shewanella baltica (strain OS195)
     244        378  Aeromonas salmonicida (strain A449)
     245        378  Shewanella baltica (strain OS155 / ATCC BAA-1091)
     246        374  Actinobacillus pleuropneumoniae serotype 5b (strain L20)
     247        374  Solanum tuberosum (Potato)
     248        374  Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
     249        373  Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)
     250        372  Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
     251        372  Burkholderia cenocepacia (strain AU 1054)
     252        372  Streptococcus agalactiae serotype III
     253        371  Prochlorococcus marinus (strain MIT 9313)
     254        370  Xanthomonas oryzae pv. oryzae
     255        369  Shewanella loihica (strain ATCC BAA-1088 / PV-4)
     256        368  Streptococcus agalactiae serotype V
     257        368  Coxiella burnetii
     258        367  Methanopyrus kandleri
     259        367  Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)
     260        363  Leptospira interrogans
     261        363  Burkholderia pseudomallei (strain 1710b)
     262        363  Prochlorococcus marinus
     263        363  Bacillus cereus subsp. cytotoxis (strain NVH 391-98)
     264        362  Rhizobium etli (strain CFN 42 / ATCC 51251)
     265        362  Geobacter sulfurreducens
     266        361  Staphylococcus aureus (strain JH1)
     267        356  Aeropyrum pernix
     268        356  Haemophilus somnus (strain 129Pt) (Histophilus somni (strain 129Pt))
     269        355  Staphylococcus aureus (strain JH9)
     270        355  Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
     271        354  Haemophilus influenzae (strain PittGG)
     272        353  Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni
     273        351  Shewanella halifaxensis (strain HAW-EB4)
     274        351  Pisum sativum (Garden pea)
     275        351  Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
     276        350  Burkholderia cenocepacia (strain HI2424)
     277        349  Legionella pneumophila (strain Paris)
     278        349  Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
     279        348  Legionella pneumophila (strain Lens)
     280        348  Rhizobium leguminosarum bv. viciae (strain 3841)
     281        346  Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
     282        346  Bacillus pumilus (strain SAFR-032)
     283        345  Nocardia farcinica
     284        345  Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)
     285        345  Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
     286        345  Sulfolobus tokodaii
     287        344  Thiobacillus denitrificans (strain ATCC 25259)
     288        344  Prochlorococcus marinus subsp. pastoris (strain CCMP 1378 / MED4)
     289        343  Psychromonas ingrahamii (strain 37)
     290        343  Glycine max (Soybean)
     291        342  Legionella pneumophila subsp. pneumophila 
     292        340  Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
     293        339  Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
     294        338  Pseudoalteromonas atlantica (strain T6c / BAA-1087)
     295        338  Shewanella sediminis (strain HAW-EB3)
     296        338  Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)
     297        337  Silicibacter pomeroyi
     298        337  Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia 
     299        336  Macaca mulatta (Rhesus macaque)
     300        336  Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / FAM18)
     301        330  Rhodopirellula baltica
     302        329  Caenorhabditis briggsae
     303        329  Geobacillus thermodenitrificans (strain NG80-2)
     304        329  Bordetella avium (strain 197N)
     305        328  Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia 
     306        328  Pseudomonas stutzeri (strain A1501)
     307        328  Mycobacterium bovis (strain BCG / Pasteur 1173P2)
     308        327  Lactococcus lactis subsp. cremoris (strain MG1363)
     309        326  Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849)
     310        326  Fusobacterium nucleatum subsp. nucleatum
     311        325  Symbiobacterium thermophilum
     312        325  Rhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118)
     313        324  Zymomonas mobilis
     314        324  Staphylococcus aureus (strain USA300 / TCH1516)
     315        322  Thermoplasma acidophilum
     316        321  Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)
     317        320  Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
     318        320  Wolinella succinogenes
     319        320  Methanococcus maripaludis
     320        319  Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
     321        319  Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
     322        318  Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
     323        318  Triticum aestivum (Wheat)
     324        317  Burkholderia pseudomallei (strain 1106a)
     325        317  Bacillus thuringiensis (strain Al Hakam)
     326        317  Streptococcus agalactiae serotype Ia
     327        317  Bacteroides thetaiotaomicron
     328        316  Corynebacterium diphtheriae
     329        316  Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)
     330        316  Rhodopseudomonas palustris (strain HaA2)
     331        314  Rhodopseudomonas palustris (strain BisB18)
     332        314  Azoarcus sp. (strain BH72)
     333        313  Marinobacter aquaeolei  (Marinobacter hydrocarbonoclasticus 
     334        313  Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
     335        313  Sinorhizobium medicae (strain WSM419) (Ensifer medicae)
     336        312  Clostridium tetani
     337        311  Methanosarcina barkeri (strain Fusaro / DSM 804)
     338        311  Nitrobacter winogradskyi (strain Nb-255 / ATCC 25391)
     339        310  Campylobacter jejuni (strain RM1221)
     340        309  Thiomicrospira crunogena (strain XCL-2)
     341        309  Brucella suis (strain ATCC 23445 / NCTC 10510)
     342        308  Hordeum vulgare (Barley)
     343        308  Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
     344        308  Brucella canis (strain ATCC 23365 / NCTC 10854)
     345        308  Alkalilimnicola ehrlichei (strain MLHE-1)
     346        307  Prochlorococcus marinus (strain NATL2A)
     347        307  Burkholderia pseudomallei (strain 668)
     348        305  Burkholderia mallei (strain NCTC 10247)
     349        304  Clostridium perfringens (strain SM101 / Type A)
     350        303  Rhodopseudomonas palustris (strain BisB5)
     351        302  Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168)
     352        301  Burkholderia mallei (strain NCTC 10229)
     353        301  Haloarcula marismortui (Halobacterium marismortui)
     354        301  Sulfolobus acidocaldarius
     355        301  Bacteroides fragilis
     356        301  Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008)
     357        301  Nitrobacter hamburgensis (strain X14 / DSM 10229)
     358        299  Burkholderia mallei (strain SAVP1)
     359        299  Gluconobacter oxydans (Gluconobacter suboxydans)
     360        299  Streptococcus thermophilus (strain CNRZ 1066)
     361        298  Mesorhizobium sp. (strain BNC1)
     362        297  Synechococcus sp. (strain CC9902)
     363        297  Cryptococcus neoformans (Filobasidiella neoformans)
     364        297  Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
     365        295  Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp.  
     366        295  Prochlorococcus marinus (strain MIT 9312)
     367        295  Staphylococcus aureus
     368        295  Bartonella henselae (Rochalimaea henselae)
     369        295  Psychrobacter arcticus (strain DSM 17307 / 273-4)
     370        293  Cavia porcellus (Guinea pig)
     371        293  Pyrobaculum aerophilum
     372        293  Nitrosomonas eutropha (strain C91)
     373        291  Helicobacter hepaticus
     374        289  Lactococcus lactis subsp. cremoris (strain SK11)
     375        289  Legionella pneumophila (strain Corby)
     376        289  Thermoplasma volcanium
     377        289  Bartonella quintana (Rochalimaea quintana)
     378        289  Streptococcus sanguinis (strain SK36)
     379        288  Synechococcus sp. (strain CC9605)
     380        288  Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288)
     381        288  Desulfotalea psychrophila
     382        286  Synechococcus sp. (strain JA-2-3B'a(2-13)) 
     383        286  Synechococcus sp. (strain JA-3-3Ab) 
     384        286  Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila 
     385        285  Streptococcus pyogenes serotype M28
     386        285  Pseudomonas putida
     387        285  Psychrobacter cryohalolentis (strain K5)
     388        285  Moorella thermoacetica (strain ATCC 39073)
     389        284  Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)
     390        283  Streptococcus pyogenes serotype M5 (strain Manfredo)
     391        282  Haemophilus somnus (strain 2336) (Histophilus somni (strain 2336))
     392        281  Rhodopseudomonas palustris (strain BisA53)
     393        281  Jannaschia sp. (strain CCS1)
     394        281  Lactobacillus sakei subsp. sakei (strain 23K)
     395        280  Bifidobacterium longum
     396        279  Ustilago maydis (Smut fungus)
     397        279  Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)
     398        279  Wigglesworthia glossinidia brevipalpis
     399        278  Spinacia oleracea (Spinach)
     400        278  Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9)
     401        278  Silicibacter sp. (strain TM1040)
     402        277  Trichodesmium erythraeum (strain IMS101)
     403        276  Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)
     404        276  Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
     405        275  Lactobacillus johnsonii
     406        274  Campylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC 11828)
     407        274  Equus caballus (Horse)
     408        274  Porphyromonas gingivalis (Bacteroides gingivalis)
     409        273  Propionibacterium acnes
     410        272  Leifsonia xyli subsp. xyli
     411        271  Gorilla gorilla gorilla (Lowland gorilla)
     412        270  Polaromonas sp. (strain JS666 / ATCC BAA-500)
     413        269  Bacteroides fragilis (strain ATCC 25285 / NCTC 9343)
     414        269  Aspergillus oryzae
     415        268  Francisella tularensis subsp. tularensis
     416        268  Bacteriophage T4
     417        268  Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)
     418        267  Blochmannia floridanus
     419        267  Acidovorax avenae subsp. citrulli (strain AAC00-1)
     420        267  Bradyrhizobium sp. (strain ORS278)
     421        266  Rhodococcus sp. (strain RHA1)
     422        266  Desulfovibrio desulfuricans (strain G20)
     423        266  Helicobacter pylori (strain HPAG1)
     424        266  Anaeromyxobacter dehalogenans (strain 2CP-C)
     425        265  Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
     426        264  Lactobacillus acidophilus
     427        264  Clostridium novyi (strain NT)
     428        263  Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis)
     429        263  Ureaplasma parvum (Ureaplasma urealyticum biotype 1)
     430        262  Mycobacterium ulcerans (strain Agy99)
     431        262  Rhodobacter capsulatus (Rhodopseudomonas capsulata)
     432        262  Chlorobium chlorochromatii (strain CaD3)
     433        261  Paracoccus denitrificans (strain Pd 1222)
     434        261  Streptococcus pyogenes serotype M12 (strain MGAS9429)
     435        260  Streptococcus pyogenes serotype M4 (strain MGAS10750)
     436        260  Chlamydophila caviae
     437        258  Corynebacterium glutamicum (strain R)
     438        258  Neisseria meningitidis serogroup C (strain 053442)
     439        257  Streptococcus pyogenes serotype M2 (strain MGAS10270)
     440        257  Desulfitobacterium hafniense (strain Y51)
     441        257  Synechococcus sp. (strain CC9311)
     442        257  Polaromonas naphthalenivorans (strain CJ2)
     443        256  Francisella tularensis subsp. holarctica (strain LVS)
     444        255  Myxococcus xanthus (strain DK 1622)
     445        255  Herminiimonas arsenicoxydans
     446        255  Prochlorococcus marinus (strain MIT 9301)
     447        255  Mycobacterium avium (strain 104)
     448        254  Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) 
     449        254  Acidovorax sp. (strain JS42)
     450        254  Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
     451        254  Vaccinia virus (strain Copenhagen) (VACV)
     452        253  Clostridium botulinum (strain ATCC 19397 / Type A)
     453        253  Thermotoga petrophila (strain RKU-1 / ATCC BAA-488 / DSM 13995)
     454        253  Pelodictyon luteolum (strain DSM 273) (Chlorobium luteolum (strain DSM 273))
     455        253  Synechococcus sp. (strain WH7803)
     456        253  Corynebacterium jeikeium (strain K411)
     457        253  Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
     458        252  Thermobifida fusca (strain YX)
     459        252  Prochlorococcus marinus (strain MIT 9515)
     460        252  Novosphingobium aromaticivorans (strain DSM 12444)
     461        251  Mycobacterium sp. (strain MCS)
     462        250  Prochlorococcus marinus (strain AS9601)
     463        250  Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
     464        248  Lactobacillus salivarius subsp. salivarius (strain UCC118)
     465        247  Bdellovibrio bacteriovorus
     466        247  Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
     467        247  Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)
     468        247  Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)
     469        246  Methylibium petroleiphilum (strain PM1)
     470        245  Alkaliphilus metalliredigens (strain QYMF)
     471        245  Prochlorococcus marinus (strain NATL1A)
     472        244  Blochmannia pennsylvanicus (strain BPEN)
     473        244  Marinomonas sp. (strain MWYL1)
     474        243  Coxiella burnetii (strain Dugway 5J108-111)
     475        243  Mycobacterium sp. (strain KMS)
     476        243  Prochlorococcus marinus (strain MIT 9215)
     477        243  Coxiella burnetii (strain RSA 331 / Henzerling II)
     478        243  Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)
     479        243  Streptococcus pyogenes serotype M12 (strain MGAS2096)
     480        242  Sulfurimonas denitrificans  (Thiomicrospira denitrificans 
     481        242  Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
     482        241  Mycobacterium sp. (strain JLS)
     483        241  Francisella tularensis subsp. tularensis (strain FSC 198)
     484        241  Clostridium difficile (strain 630)
     485        240  Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
     486        239  Prochlorococcus marinus (strain MIT 9303)
     487        238  Francisella tularensis subsp. novicida (strain U112)
     488        238  Lactobacillus casei (strain ATCC 334)
     489        237  Treponema denticola
     490        236  Baumannia cicadellinicola subsp. Homalodisca coagulata
     491        236  Francisella tularensis subsp. holarctica (strain OSU18)
     492        235  Bacillus stearothermophilus (Geobacillus stearothermophilus)
     493        234  Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)
     494        234  Acaryochloris marina (strain MBIC 11017)
     495        234  Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)
     496        234  Methanococcus vannielii (strain SB / ATCC 35089 / DSM 1224)
     497        233  Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
     498        232  Sphingopyxis alaskensis (Sphingomonas alaskensis)
     499        232  Methanococcus maripaludis (strain C7 / ATCC BAA-1331)
     500        232  Syntrophus aciditrophicus (strain SB)
     501        231  Chlamydomonas reinhardtii
     502        231  Hyphomonas neptunium (strain ATCC 15444)
     503        230  Pediococcus pentosaceus (strain ATCC 25745 / 183-1w)
     504        229  Verminephrobacter eiseniae (strain EF01-2)
     505        229  Chlorobium phaeobacteroides (strain DSM 266)
     506        228  Helicobacter acinonychis (strain Sheeba)
     507        228  Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
     508        228  Pelobacter propionicus (strain DSM 2379)
     509        227  Maricaulis maris (strain MCS10)
     510        227  Alkaliphilus oremlandii (strain OhILAs) (Clostridium oremlandii (strain OhILAs))
     511        227  Deinococcus geothermalis (strain DSM 11300)
     512        226  Chlamydia trachomatis (strain A/HAR-13 / ATCC VR-571B)
     513        225  Francisella tularensis subsp. tularensis (strain WY96-3418)
     514        224  Cricetulus griseus (Chinese hamster)
     515        224  Protochlamydia amoebophila (strain UWE25)
     516        222  Francisella tularensis subsp. holarctica (strain FTA)
     517        222  Syntrophomonas wolfei subsp. wolfei (strain Goettingen)
     518        221  Desulfotomaculum reducens (strain MI-1)
     519        221  Caulobacter sp. (strain K31)
     520        220  Frankia sp. (strain CcI3)
     521        220  Dinoroseobacter shibae (strain DFL 12)
     522        219  Bartonella tribocorum (strain CIP 105476 / IBS 506)
     523        218  Synechococcus sp. (strain RCC307)
     524        218  Lactobacillus brevis (strain ATCC 367 / JCM 1170)
     525        217  Felis silvestris catus (Cat)
     526        217  Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081)
     527        217  Chlamydophila abortus
     528        217  Porphyra purpurea
     529        217  Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
     530        216  Bartonella bacilliformis (strain ATCC 35685 / KC583)
     531        216  Methanococcoides burtonii (strain DSM 6242)
     532        215  Leptospira borgpetersenii serovar Hardjo-bovis (strain L550)
     533        215  Rickettsia akari (strain Hartford)
     534        214  Klebsiella pneumoniae
     535        214  Dehalococcoides sp. (strain CBDB1)
     536        213  Dehalococcoides ethenogenes (strain 195)
     537        211  Rickettsia canadensis (strain McKiel)
     538        211  Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)
     539        210  Rickettsia rickettsii (strain Sheila Smith)
     540        209  Gibberella zeae (Fusarium graminearum)
     541        208  Mycobacterium gilvum (strain PYR-GCK) (Mycobacterium flavescens 
     542        208  Streptococcus suis (strain 98HAH33)
     543        208  Porphyra yezoensis
     544        208  Francisella philomiragia subsp. philomiragia (strain ATCC 25017)
     545        208  Anaeromyxobacter sp. (strain Fw109-5)
     546        208  Granulobacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
     547        207  Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154)
     548        206  Nitratiruptor sp. (strain SB155-2)
     549        206  Pelagibacter ubique
     550        206  Mesocricetus auratus (Golden hamster)
     551        205  Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903)
     552        204  Chlamydophila felis (strain Fe/C-56)
     553        204  Salinibacter ruber (strain DSM 13855)
     554        203  Encephalitozoon cuniculi
     555        203  Tropheryma whipplei (strain TW08/27) (Whipple's bacillus)
     556        203  Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC BAA-365)
     557        203  Prosthecochloris vibrioformis  (Chlorobium vibrioforme subsp. thiosulfatophilum  (Chlorobium phaeovibrioides 
     558        203  Psychrobacter sp. (strain PRwf-1)
     559        202  Magnetococcus sp. (strain MC-1)
     560        202  Tropheryma whipplei (strain Twist) (Whipple's bacillus)
     561        202  Lactobacillus reuteri (strain ATCC 23272 / DSM 20016 / F275)
     562        200  Vaccinia virus (strain Western Reserve / WR) (VACV)


   
   3.3  Taxonomic distribution of the sequences

   

   Kingdom        sequences (% of the database)
    Archaea           14637 (  4%)
    Bacteria         222942 ( 57%)
    Eukaryota        140754 ( 36%)
    Viruses           12363 (  3%)


   Within Eukaryota:

   

    Category            sequences (% of Eukaryota) (% of the complete database)
     Human                  19930 ( 14%)           (  5%)
     Other Mammalia         42795 ( 30%)           ( 11%)
     Other Vertebrata       13889 ( 10%)           (  4%)
     Viridiplantae          23238 ( 17%)           (  6%)
     Fungi                  21935 ( 16%)           (  6%)
     Insecta                 5522 (  4%)           (  1%)
     Nematoda                3764 (  3%)           (  1%)
     Other                   9681 (  7%)           (  2%)


   3.4  Annotation of high-priority organisms


   


   



4.  SEQUENCE SIZE

   Repartition of the sequences by size (excluding fragments)

               From   To  Number             From   To   Number
                  1-  50    6397             1001-1100     2920
                 51- 100   29131             1101-1200     1986
                101- 150   41790             1201-1300     1572
                151- 200   41109             1301-1400     1426
                201- 250   40870             1401-1500     1112
                251- 300   35938             1501-1600      553
                301- 350   34995             1601-1700      435
                351- 400   30746             1701-1800      380
                401- 450   25270             1801-1900      350
                451- 500   20933             1901-2000      274
                501- 550   14736             2001-2100      173
                551- 600   10881             2101-2200      244
                601- 650    9198             2201-2300      219
                651- 700    6482             2301-2400      155
                701- 750    5298             2401-2500      111
                751- 800    3902             >2500          860
                801- 850    3404
                851- 900    3637
                901- 950    2976
                951-1000    2101

   


   The average sequence length in UniProtKB/Swiss-Prot is 359 amino acids.

   The shortest sequence is   GWA_SEPOF (P83570):     2 amino acids.
   The longest sequence is  TITIN_MOUSE (A2ASS6): 35213 amino acids.


5.  JOURNAL CITATIONS

   Note: the following citation statistics reflect the number of distinct
         journal citations.

   Total number of journals cited in this release of UniProtKB/Swiss-Prot: 1918


   5.1 Table of the frequency of journal citations

        Journals cited 1x:  624
                       2x:  267
                       3x:  129
                       4x:  103
                       5x:   72
                       6x:   56
                       7x:   39
                       8x:   37
                       9x:   36
                      10x:   23
                  11- 20x:  151
                  21- 50x:  151
                  51-100x:   86
                    >100x:  144


   5.2  List of the most cited journals in UniProtKB/Swiss-Prot

   Nb    Citations   Journal name
   --    ---------   -------------------------------------------------------------
    1        16294   Journal of Biological Chemistry
    2         7637   Proceedings of the National Academy of Sciences of the U.S.A.
    3         4673   Journal of Bacteriology
    4         4396   Gene
    5         4186   Biochemical and Biophysical Research Communications
    6         4175   Nucleic Acids Research
    7         3742   FEBS Letters
    8         3493   Biochemistry
    9         3472   The EMBO Journal
   10         3115   Molecular and Cellular Biology
   11         3007   European Journal of Biochemistry
   12         2962   Nature
   13         2817   Biochimica et Biophysica Acta
   14         2690   Journal of Molecular Biology
   15         2430   Genomics
   16         2411   Cell
   17         2012   Biochemical Journal
   18         1885   Science
   19         1600   Journal of Virology
   20         1582   Molecular Microbiology
   21         1425   Journal of Cell Biology
   22         1417   Plant Molecular Biology
   23         1288   Molecular and General Genetics
   24         1222   Virology
   25         1195   Nature Genetics
   26         1191   Genes and Development
   27         1191   Human Molecular Genetics
   28         1121   Journal of Biochemistry
   29         1099   Oncogene
   30         1091   The American Journal of Human Genetics
   31         1085   Plant Physiology
   32          982   Development
   33          918   Journal of Immunology
   34          900   Human Mutation
   35          868   Genetics
   36          848   Molecular Biology of the Cell
   37          812   Infection and Immunity
   38          792   Structure
   39          768   Journal of General Virology
   40          755   Archives of Biochemistry and Biophysics
   41          723   Yeast
   42          703   The Plant Cell
   43          698   Blood
   44          662   Microbiology
   45          647   Molecular Cell
   46          614   Developmental Biology
   47          607   Journal of Cell Science
   48          594   Cancer Research
   49          594   FEMS Microbiology Letters
   50          584   The Plant Journal
   51          563   Human Genetics
   52          563   Nature Structural Biology
   53          529   Mechanisms of Development
   54          521   Current Biology
   55          511   Current Genetics
   56          474   Journal of Neuroscience
   57          471   Applied and Environmental Microbiology
   58          465   Journal of Clinical Investigation
   59          464   Acta Crystallographica, Section D
   60          462   Neuron
   61          460   Protein Science
   62          458   Mammalian Genome
   63          421   The Journal of Experimental Medicine
   64          420   Immunogenetics
   65          413   Molecular Endocrinology
   66          413   Toxicon
   67          410   Molecular and Biochemical Parasitology
   68          406   American Journal of Physiology
   69          378   Journal of Neurochemistry
   70          365   Endocrinology
   71          359   Journal of Molecular Evolution
   72          353   DNA and Cell Biology
   73          351   The Journal of Clinical Endocrinology and Metabolism
   74          343   DNA Sequence
   75          332   Molecular Biology and Evolution
   76          312   Bioscience, Biotechnology, and Biochemistry
   77          306   Journal of Medical Genetics
   78          306   Brain Research. Molecular Brain Research
   79          286   Biological Chemistry Hoppe-Seyler
   80          279   Proteins
   81          272   Cytogenetics and Cell Genetics
   82          260   Comparative Biochemistry and Physiology
   83          256   Journal of Investigative Dermatology
   84          255   Peptides
   85          245   Journal of General Microbiology
   86          245   Molecular Pharmacology
   87          244   Antimicrobial Agents and Chemotherapy
   88          238   Biology of Reproduction
   89          237   Plant and Cell Physiology
   90          234   Nature Cell Biology
   91          232   Experimental Cell Research
   92          224   Genome Research
   93          215   Hoppe-Seyler's Zeitschrift fur Physiologische Chemie
   94          211   Virus Research
   95          207   Neurology
   96          194   Developmental Dynamics
   97          193   Molecular Plant-Microbe Interactions
   98          193   RNA
   99          191   DNA Research
  100          188   European Journal of Immunology
  101          182   Biochimie
  102          180   Tissue Antigens
  103          173   Annals of Neurology
  104          173   European Journal of Human Genetics
  105          165   Journal of Human Genetics
  106          163   Molecular and Cellular Endocrinology
  107          163   Immunity
  108          163   Genes to Cells
  109          162   Planta
  110          159   DNA
  111          158   Developmental Cell
  112          155   Molecular Phylogenetics and Evolution
  113          154   American Journal of Medical Genetics
  114          152   Hemoglobin
  115          149   Archives of Microbiology
  116          149   Eukaryotic cell
  117          148   The New England Journal of Medicine
  118          146   Bioorganicheskaia Khimiia
  119          143   Insect Biochemistry and Molecular Biology
  120          137   Investigative Ophthalmology and Visual Science
  121          136   Molecular Reproduction and Development
  122          136   Diabetes
  123          134   Glycobiology
  124          133   Animal Genetics
  125          131   Molecular Immunology
  126          129   General and Comparative Endocrinology
  127          127   Molecular and Cellular Neuroscience
  128          124   International Journal of Cancer
  129          121   Archives of Virology
  130          119   Agricultural and Biological Chemistry
  131          116   The FASEB Journal
  132          112   British Journal of Haematology
  133          111   Molecular Genetics and Metabolism
  134          110   EMBO Reports
  135          109   Journal of Protein Chemistry
  136          106   Clinical Genetics
  137          106   Biological Chemistry
  138          105   Molecular Genetics and Genomics
  139          104   Journal of Neuroscience Research
  140          104   Journal of Cellular Biochemistry
  141          103   Neuroscience Letters
  142          103   Journal of Molecular Endocrinology
  143          103   Journal of Lipid Research
  144          101   Biochemistry and Molecular Biology International


6.  STATISTICS FOR SOME LINE TYPES

The following table summarizes the total number of some UniProtKB/Swiss-Prot lines,
as well as the number of entries with at least one such line, and the
frequency of the lines.

                                   Total    Number of  Average
Line type / subtype                number   entries    per entry
---------------------------------  -------- ---------  ---------

   References (RL)                     713537              1.83
1     Journal                          578611    305616    1.48
2     Submitted to EMBL/GenBank/DDBJ   127885    117829    0.33
3     Submitted to other databases       5057      4669    0.01
4     Book citation                       592       582   <0.01
5     Plant Gene Register                 540       528   <0.01
6     Thesis                              420       418   <0.01
7     Unpublished observations            285       281   <0.01
8     Patent                              141       139   <0.01
9     Worm Breeder's Gazette                6         6   <0.01

Total number of distinct authors cited in UniProtKB/Swiss-Prot: 262148.

   Comments (CC)                      1615187              4.13
1     SIMILARITY                       452484    367283    1.16
2     FUNCTION                         280266    269770    0.72
3     SUBCELLULAR LOCATION             223231    219059    0.57
4     CATALYTIC ACTIVITY               156747    143258    0.40
5     SUBUNIT                          153224    153224    0.39
6     PATHWAY                           91670     79897    0.23
7     COFACTOR                          64979     59572    0.17
8     TISSUE SPECIFICITY                29402     29402    0.08
9     PTM                               28721     23515    0.07
10    MISCELLANEOUS                     26848     24501    0.07
11    DOMAIN                            24216     21357    0.06
12    ALTERNATIVE PRODUCTS              16768     16768    0.04
13    SEQUENCE CAUTION                  10295     10295    0.03
14    INTERACTION                        9420      9420    0.02
15    INDUCTION                          9092      9092    0.02
16    DEVELOPMENTAL STAGE                7537      7537    0.02
17    WEB RESOURCE                       6282      5109    0.02
18    ENZYME REGULATION                  6248      6248    0.02
19    CAUTION                            5292      5187    0.01
20    DISEASE                            4348      2996    0.01
21    MASS SPECTROMETRY                  3526      2699    0.01
22    BIOPHYSICOCHEMICAL PROPERTIES      2202      2202    0.01
23    POLYMORPHISM                        710       681   <0.01
24    RNA EDITING                         544       544   <0.01
25    ALLERGEN                            445       445   <0.01
26    TOXIC DOSE                          374       366   <0.01
27    BIOTECHNOLOGY                       236       234   <0.01
28    PHARMACEUTICAL                       80        80   <0.01

   Features (FT)                      2427091              6.21
1     CHAIN                            396977    386803    1.02
2     TRANSMEM                         238504     50971    0.61
3     METAL                            178701     44721    0.46
4     BINDING                          126185     39828    0.32
5     DOMAIN                           118207     68155    0.30
6     CONFLICT                         107783     37444    0.28
7     STRAND                           106870     10129    0.27
8     MOD_RES                          104052     37107    0.27
9     TOPO_DOM                         103947     21172    0.27
10    HELIX                            103736     10660    0.27
11    ACT_SITE                          94410     55812    0.24
12    CARBOHYD                          86714     22306    0.22
13    DISULFID                          84881     21510    0.22
14    REPEAT                            72737     11060    0.19
15    NP_BIND                           69671     48076    0.18
16    REGION                            60293     33528    0.15
17    VARIANT                           59464     12735    0.15
18    COMPBIAS                          37160     21344    0.10
19    VAR_SEQ                           35189     14936    0.09
20    SIGNAL                            29265     29255    0.07
21    MOTIF                             25711     16695    0.07
22    TURN                              25708      8579    0.07
23    SITE                              24924     14367    0.06
24    ZN_FING                           24421      9934    0.06
25    MUTAGEN                           24077      5827    0.06
26    COILED                            14825      9805    0.04
27    INIT_MET                          12314     12314    0.03
28    NON_TER                           10980      8393    0.03
29    LIPID                              9389      6024    0.02
30    PROPEP                             9362      7804    0.02
31    DNA_BIND                           8759      8097    0.02
32    PEPTIDE                            7506      4583    0.02
33    TRANSIT                            5597      5514    0.01
34    CA_BIND                            3348      1389    0.01
35    CROSSLNK                           2969      2060    0.01
36    NON_CONS                           1447       584   <0.01
37    UNSURE                              668       224   <0.01
38    NON_STD                             340       266   <0.01

   Cross-references (DR)              6890658             17.64
1     InterPro                         940478    362099    2.41
2     EMBL                             674786    381821    1.73
3     GO                               651575    259330    1.67
4     Pfam                             496864    348358    1.27
5     PROSITE                          354235    222028    0.91
6     RefSeq                           353595    323554    0.91
7     GeneID                           339717    323324    0.87
8     KEGG                             299425    279467    0.77
9     GenomeReviews                    255202    237670    0.65
10    HAMAP                            203811    203712    0.52
11    HOGENOM                          197998    197998    0.51
12    TIGRFAMs                         184582    172915    0.47
13    Gene3D                           176938    146995    0.45
14    BioCyc                           145866    139351    0.37
15    PANTHER                          140796    129954    0.36
16    PRINTS                           123385    100879    0.32
17    NMPDR                            116721    116721    0.30
18    PIR                              110871    101204    0.28
19    ProDom                           108689    105859    0.28
20    SMART                            104025     79096    0.27
21    HSSP                              84033     84033    0.22
22    UniGene                           78073     72463    0.20
23    HOVERGEN                          74716     74695    0.19
24    Ensembl                           66420     64911    0.17
25    PIRSF                             57574     57574    0.15
26    ArrayExpress                      52970     52970    0.14
27    PDBsum                            50389     12753    0.13
28    PDB                               50389     12753    0.13
29    SMR                               49871     49871    0.13
30    GermOnline                        41987     41375    0.11
31    TIGR                              31484     30787    0.08
32    CleanEx                           30195     29561    0.08
33    HGNC                              18746     18613    0.05
34    LinkHub                           18097     18097    0.05
35    IntAct                            16422     16422    0.04
36    PharmGKB                          15817     15808    0.04
37    MGI                               15611     15560    0.04
38    MIM                               15107     12029    0.04
39    PhosphoSite                       14849     14849    0.04
40    H-InvDB                           11267      9572    0.03
41    DIP                                8998      8948    0.02
42    MEROPS                             7201      6905    0.02
43    RGD                                6976      6971    0.02
44    TAIR                               6951      6837    0.02
45    SGD                                6641      6539    0.02
46    CYGD                               6628      6524    0.02
47    DrugBank                           5331      1630    0.01
48    PeptideAtlas                       5168      5168    0.01
49    GeneDB_Spombe                      4460      4419    0.01
50    EcoGene                            4332      4329    0.01
51    EchoBASE                           4159      4124    0.01
52    WormPep                            3881      3186    0.01
53    Gramene                            3735      3731    0.01
54    FlyBase                            3688      3560    0.01
55    WormBase                           3577      3493    0.01
56    Reactome                           3416      2069    0.01
57    HPA                                2985      2565    0.01
58    SubtiList                          2817      2816    0.01
59    Orphanet                           2590      1683    0.01
60    dictyBase                          2429      2343    0.01
61    GeneFarm                           2240      2220    0.01
62    ZFIN                               2077      2061    0.01
63    StyGene                            1651      1647   <0.01
64    TubercuList                        1470      1434   <0.01
65    SWISS-2DPAGE                       1184      1182   <0.01
66    PseudoCAP                          1179      1170   <0.01
67    ListiList                          1129      1121   <0.01
68    REPRODUCTION-2DPAGE                1029       941   <0.01
69    AGD                                 769       763   <0.01
70    LegioList                           699       697   <0.01
71    PhotoList                           691       691   <0.01
72    Leproma                             650       647   <0.01
73    PeroxiBase                          496       485   <0.01
74    World-2DPAGE                        495       495   <0.01
75    CGD                                 471       471   <0.01
76    MaizeGDB                            468       463   <0.01
77    ProMEX                              422       422   <0.01
78    DisProt                             397       394   <0.01
79    OGP                                 380       378   <0.01
80    SagaList                            373       372   <0.01
81    REBASE                              351       343   <0.01
82    ECO2DBASE                           351       299   <0.01
83    GlycoSuiteDB                        282       282   <0.01
84    BuruList                            262       262   <0.01
85    PHCI-2DPAGE                         244       244   <0.01
86    VectorBase                          228       221   <0.01
87    MypuList                            198       198   <0.01
88    DOSAC-COBS-2DPAGE                   152       150   <0.01
89    Aarhus/Ghent-2DPAGE                 126        96   <0.01
90    Siena-2DPAGE                        102       102   <0.01
91    HSC-2DPAGE                           85        85   <0.01
92    2DBase-Ecoli                         84        84   <0.01
93    PhosSite                             70        70   <0.01
94    Cornea-2DPAGE                        67        67   <0.01
95    COMPLUYEAST-2DPAGE                   59        59   <0.01
96    euHCVdb                              55        44   <0.01
97    PMMA-2DPAGE                          52        52   <0.01
98    PptaseDB                             31        31   <0.01
99    Rat-heart-2DPAGE                     28        28   <0.01
100   ANU-2DPAGE                           22        22   <0.01



7.  MISCELLANEOUS STATISTICS

4375 entries are encoded on a mitochondrion, and 3423 are encoded on a plasmid.

9658 entries are encoded on a plastid, 
of which 16 are encoded on apicoplasts, 
9263 on chloroplasts, 
 on chromatophores,
145 on cyanelles, 
124 on non-photosynthetic plastids and 
110 on unspecified types of plastid.




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