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The UniProtKB/Swiss-Prot Human Proteome Initiative
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HPI Status report

UniProtKB/Swiss-Prot Release 57.3 of 26-May-2009: 470369 entries (Release statistics)

Total number of manually annotated mammalian entries in UniProtKB/Swiss-Prot: 64,541

Total number of manually annotated HUMAN entries in UniProtKB/Swiss-Prot: 20,330

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 14,179 34 0.70 7,424 36%
Variants (disease mutations and polymorphisms): 57,491 1363 2.83 11,716 57%
Post-translational modifications (experimentally proven or potential): 67,984 303 3.34 12,017 59%
References to published articles: 116,470 / 46,906 180 5.73 20,200 99%
Comment blocks: 114,590 / 41,791 34 5.64 19,707 96%
Feature lines: 523,946 4258 25.77 20,330 100%
Cross-references:
EMBL protein_ids: 138,079 / 137,290 723 6.79 20,206 99%
InterPro: 55,091 / 7,305 22 2.71 17,190 84%
PDB (3D-structures): 31,862 / 29,878 516 1.57 3,740 18%
MIM catalog of human genes and genetic disorders: 15,699 / 14,789 14 0.77 12,391 60%
HGNC gene nomenclature: 19,432 / 19,293 14 0.96 19,262 94%

Total number of manually annotated MOUSE entries in UniProtKB/Swiss-Prot: 16,140

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 7,415 20 0.46 4,389 27%
Variants (disease mutations and polymorphisms): 1,165 37 0.07 358 2%
Post-translational modifications (experimentally proven or potential): 56,288 216 3.49 10,260 63%
References to published articles: 48,986 / 17,875 50 3.04 15,903 98%
Comment blocks: 82,498 / 33,121 22 5.11 15,811 97%
Feature lines: 258,973 612 16.05 16,140 100%
Cross-references:
EMBL protein_ids: 69,681 / 69,628 111 4.32 16,003 99%
InterPro: 46,039 / 7,132 20 2.85 14,393 89%
PDB (3D-structures): 5,346 / 4,966 300 0.33 970 6%
Mouse Genome Informatics: 15,986 / 15,921 12 0.99 15,935 98%

Total number of manually annotated RAT entries in UniProtKB/Swiss-Prot: 7,384

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 1,407 18 0.19 799 10%
Variants (disease mutations and polymorphisms): 274 30 0.04 115 1%
Post-translational modifications (experimentally proven or potential): 28,167 204 3.81 5,152 69%
References to published articles: 15,376 / 9,442 26 2.08 6,956 94%
Comment blocks: 38,238 / 18,272 24 5.18 7,267 98%
Feature lines: 112,158 314 15.19 7,384 100%
Cross-references:
EMBL protein_ids: 15,092 / 15,077 152 2.04 7,309 98%
InterPro: 22,279 / 5,197 20 3.02 6,748 91%
PDB (3D-structures): 3,018 / 2,875 136 0.41 422 5%
Rat Genome Database: 7,270 / 7,250 3 0.98 7,266 98%

For more detailed information about the taxonomic distribution of UniProtKB/Swiss-Prot entries, see the corresponding section in the Release statistics.

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