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HAMAP: Leptospira interrogans complete proteome

General information

Species:  Leptospira interrogans
Species code: LEPIN
Taxonomy: Bacteria; Spirochaetes; Spirochaetales; Leptospiraceae; Leptospira (TaxID: 173) [NEWT/ NCBI]
Description: Leptospira interrogans causes leptospirosis whose manifestations are fever, headache, malaise, myalgia, occasionally meningitidis, sometimes jaundice, renal insufficiency, anemia and hemorrhage of the skin. Rarely lethal. Worldwide spread except in polar regions. Contamination occurs through contact of the skin or mucous membranes with contaminated water, soil or vegetation or through direct contact with urine or tissues of infected animals. Farm and pet animals, including cattle, dogs, horses and swine, rats and other rodents act as the normal carrier host; wild animals, including deer, squirrels, foxes, skunks and even reptiles and amphibians may be infected.
Properties: Presence of flagella: Yes
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins: 1
Statistics: Number of LEPIN entries in the UniProt Knowledgebase: 4690 (376 in UniProtKB/Swiss-Prot + 4314 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    56601 / Serogroup Icterohaemorrhagiae / Serovar lai
Genome structure:
• Chromosome I EMBL accession number AE010300 (circular; 4,332,241 bp) (download entry) (download Genome Reviews).
• Chromosome II EMBL accession number AE010301 (circular; 358,943 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] MEDLINE=22598143; PubMed=12712204; [ NCBI , EBI , Israel , Japan ]
Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X., Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X., Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H., Yin H.-F., Zhang Y., Zhu G.-F., Wan M., Huang H.-L., Qian Z., Wang S.-Y., Ma W., Yao Z.-J., Shen Y., Qiang B.-Q., Xia Q.-C., Guo X.-K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.-M., Shi M.-H., Chen Z., Xu J.-G., Zhao G.-P. ;
"Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing.";
Nature 422:888-893(2003).
Web links:
CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Leptospira&GLspecies=interrogans&GLstrain=56601
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid189518%5Borgn%5D
GenoList: http://bioinfo.hku.hk/GenoList/index.pl?database=leptolist
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Lint_56601
Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Leptospira_interrogans.html
PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p293_Lep_inter
TIGR CMR: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=ntli02
 EBI Proteome Analysis page



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