The CodonSuite server takes as input inframe coding DNA sequences and then performs various codon-based comparisons- codon-based alignments, a codon distance-based tree, SynPAM distance estimates and estimates of Nei and Gojoboris dN and dS.
Sequence Translation (Transeq, Sixpack) is used to translate nucleic acid sequence to corresponding peptide sequences.
Back-translation (Backtranseq, Backtranambig) is used to predict the possible nucleic acid sequence that a specified peptide sequence has originated from.
Differences in codon usage preference among organisms lead to a variety of problems concerning heterologous gene expression but can be overcome by rational gene design and gene synthesis. The gcua tool displays the codon quality either in codon usage frequency values or relative adaptiveness values
Along with sequence data for Pfam gene families and protein domains, PANDITplus provides access to data on protein interactions, functional and chemical pathway annotation, gene expression, and association with disease, and pre-computed estimates from evolutionary codon models.
Translation of a nucleotide (DNA/RNA) sequence to a protein sequence.