PROSITE entry PS51797

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission

General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51797
Entry name [info]	TCTP_3
Accession [info]	PS51797
Entry type [info]	MATRIX
Date [info]	01-MAY-2016 CREATED; 13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00768
Associated ProRule [info]	PRU01133

Name and characterization of the entry

Description [info]

Translationally controlled tumor protein (TCTP) domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=170;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=165;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.2623415; R2=0.0062509; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=12242.4501953; R2=10.6677265; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=918; H_SCORE=22035; N_SCORE=9.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=518; H_SCORE=17768; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-51; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='M';  M= -60, -14,-128, -38,   2,-123,-104, -15,-114, -53, 148,-117,-118,-106,-113,-117, -54, -90,-120, -97;
/M: SY='I';  M=-112,-123,-121,-114, -99,-129,-115,  79,  45,  34,  16, -39, -38, -31, -13,-115, -50, -51,-117,  14;
/M: SY='I';  M=-107,-120,-131,-128, -98,-135,-131,  90,-124,  -7, -85,-124,-123,-123,-127,-117, -20,  68,-126,-106;
/M: SY='Y';  M=-118,-125, -31,-121,  72, -69, -94,-102, -59, -58, -99, -26,-129,-114,-113,-114, -29, -56,  10, 121;
/M: SY='K';  M= -45,-124,-105, -93,-123, -60, -29,-119,  96,-120, -48, -30,-113,  46,  20,-102,  11, -24,  28,-110;
/M: SY='D';  M=-114,  66, 117, -37,-129, -27,-104,-130,-105, -56,-126, -87,-117,-105,-113,-104,-106,-126,-145, -37;
/M: SY='I';  M=  19, -27,-127,-120, -50,-126,-122,  74, -25,  35,  -3,-120,-123, -19, -49, -58,-105,  33,-121, -38;
/M: SY='I';  M= -25,  26,-130,-127,  71,-129,-121,  71,-123,  18,  17,-122,-126,-123,-124, -48, -31,   8,-111, -29;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='T';  M= -52,-112,-106,-108, -25, -15,-111, -20,-105,-115,-111, -21, -47,-104, -37,  76,  89,-104,-130,-112;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='G';  M=-103,-124,  39, -67,-129,  84,  46,-132, -18,-130,-120,  45,-116, -14,-113, -46,-110, -62,-129,-118;
/M: SY='D';  M= -46,-126, 110,   1,-133, -66,  -8,-131,   2,-129,-125,   6, -47,   2,-105,  -9,-103,-127,-142,-116;
/M: SY='E';  M=-107,-128, -13, 112,-127,-123, -10, -53, -91, -52,-116,-104, -45, -14,-101, -38,-107, -44,-128,-118;
/M: SY='M';  M=-110,-118, -40, -54, -96,-128,-112,  25, -39,  54, 111,-121, -49,-112,-116,-119,-107,  24,-122,-102;
/M: SY='F';  M= -29,  63, -40, -39,  96,-126,-117,  10,-121,  -1,  43,-120,-128,-124,-122, -31,-109,   4,   5, -84;
/M: SY='S';  M= -45, -15,-102,   1,-120,-102,-108,-118,-103, -61,-115, -94,-111, -14,-109, 102,  46,-110,-130,-114;
/M: SY='D';  M=-113,-127, 117,   8,-130, -65,-102, -25,-102, -62,-124, -39,-114,-101, -48, -47, -32,-123,-145,-117;
/M: SY='S';  M=  53,  11, -27, -35,-118, -62,-113,  18, -37,-111,-108, -21, -36,   1,-111,  57,  45, -25,-128,-115;
/M: SY='Y';  M= -27,  -2, -15,-120,  83,-124,   8, -24,-116, -57, -20, -39, -43,-116, -45, -60,-111,  -9,  29,  96;
/M: SY='P';  M=  -6, -25,  18, -47, -53,-114,-108, -45,  72,-124,-114,  13,  81, -42,   0, -68, -13,-118,-126,-117;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='M';  M= -32, -28, -48, -49,  -5, -49,  12,  32,-113,  11,  82, -45,  22, -22, -46, -35,  -1,  14,-115,  45;
/M: SY='K';  M=-108,-123, -24,  35,-118,-119, -20, -24,  73, -46, -45, -38, -19,  26,  -1, -23,  29,  -3,  27, -30;
/I:         I=-36; MD=-90;
/M: SY='E';  M= -45,-147, -14,  46, -27, -39,-133, -37, -56, -46,-136, -18, -19,-123,-134, -15,   4, -82,-150, -42; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='E';  M= -58,-122,   4,  46,-109, -37,-115,  18,  14,  44, -97, -38, -15,-106,-111, -46,  12,  10,-128,-112; D=-36;
/I:         I=-36; DM=-90;
/M: SY='V';  M= -15, -38,   7,  39,  21, -40,  -1,  -1, -13, -25,   5, -62,   2,-108,-113,-107,   6,  62,-125,-106;
/M: SY='D';  M= -41,-123,  86,  37, -54,   7,  18,-122, -70,-124,-119,  36, -38, -99,-109,  29, -71, -10,-137,-115;
/M: SY='D';  M=-106,-125,  85, -23, -26,  61,-108, -41, -14, -67,-121,   0,  21,-105,-113,  -5,-107,-124,-131,-117;
/M: SY='V';  M= -33,  26, -48,-122,  47,  11,-121,  30, -60,  25,  10,-119, -55,-120, -46, -63,-106,  58,-119,-100;
/M: SY='C';  M= -14,  57,-126,-123,  32, -13,  -4,  30,-121,  36,  22,-119,-126,-119,-122, -35, -38,  41,-117,  18;
/M: SY='Y';  M=-117,-126,-125, -59,  53, -59,-103,  -4,-116,  15,  -3, -42,-128,-115, -46, -56,-113, -34, 100, 102;
/M: SY='E';  M=-107, -17, -88, 100,   7, -53,-104,-118,  14,-116, -31, -27,-108,  -3, -27,-104,  -8,  -5,-124,-113;
/M: SY='V';  M= -55,  35,-129,-124,  27,-129,-128,  15,-120, -69, -92,-122,-126,-123, -34, -35, -46,  96,-127,-104;
/M: SY='E';  M=-108,  -9,  53,  61,-124, -64,-105, -40,  51,-120,-114, -23, -26,   9, -10, -39,  31, -22,-129, -54;
/M: SY='C';  M=   5,  81,-113,-117,-123,  76,-118,-126,-113, -78,-117,-101, -25,-112, -53,  33,  18,-118,  26,-120;
/M: SY='K';  M= -32,-123,-103,  -6,-121,-116,-105,-118,  94, -48,-110, -23,-113,  15,  29, -15,  -5, -22,-121, -33;
/M: SY='M';  M=-111,-120, -44,-114,  16, -43,  35,  -9,  -8,  16,  90,  11,-121,-106,  15, -60,  11, -27,  18,  52;
/I:         I=-8; MD=-19;
/M: SY='V';  M=-105,-119,-120, -10,-103,-128,-123,  63, -23, -55,  -6,-116,-120, -18, -68, -12,  30,  68,   8, -14; D=-8;
/I:         I=-8; MD=-19;
/M: SY='T';  M= -15,-114,-107, -21,-116,-111,-113,  -9, -11, -53,-108, -17, -40, -41, -24,  63,  76,   3,   8,-112; D=-8;
/I:         I=-8; MD=-19;
/M: SY='R';  M= -66,-125, -63,  33, -66, -67,-109,  10,  59, -35, -33, -37, -30,  -9,  62,-108, -45,  23,-125,-112; D=-8;
/I:         I=-8; MD=-19;
/M: SY='G';  M= -16,-126,  34,-107,-130,  42,-115, -41,  40,-126,   0,  -1,-120, -40, -32,  26,  12, -49,-134,-122; D=-8;
/I:         I=-8; MD=-19;
/M: SY='E';  M=   7,-134,  31,  47, -70,  -8,-118, -72, -33, -39,-125,  12,-125,  23, -66, -18, -32, -49,-141,-128; D=-8;
/I:         I=-8; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='G';  M=  -4,-133,   3, -23,  17,  42,-130,  33,-127, -52,-115, -19, -39,-126,-132, -77, -29,   3,-133,-119; D=-8;
/I:         I=-8; DM=-19;
/M: SY='D';  M= -13,-126,  82,  35, -57, -18,-110, -62,-107, -78,-120,  21,  -6,-105,-115, -11,  -5,   6,-140,-120; D=-8;
/I:         I=-8; DM=-19;
/M: SY='D';  M=  -6,-125,  79,  12, -12, -25,-110,  19, -35,-119,-117,  42,-119,-107,-115, -18,  -5, -32,-137,-117; D=-8;
/I:         I=-8; DM=-19;
/M: SY='V';  M=  -3,-121,  19,  -3,  -6,-118,  13,   5, -70, -60, -27, -19, -27, -21, -42,  42,  -9,  46,-128,  -4; D=-8;
/I:         I=-8; DM=-19;
/M: SY='D';  M= -28,-123,  65, -58, -43,  -5, -18, -13, -38,  56, -97, -61,-125,-113,-118, -45,-110, -12,-126,   4; D=-8;
/I:         I=-8; DM=-19;
/M: SY='I';  M= -13, -31, -54,  11,  12,  -7,  -4,  77,-119,  16, -93,-117, -32,-115,-122, -39, -12, -38,-120, -13; D=-8;
/I:         I=-8; DM=-19;
/M: SY='G';  M= -36, -15, -47, -53,-126,  97,-117, -58,-116, -69,-120, -23, -45,-113, -75, -15, -45,-126,-123, -21; D=-8;
/I:         I=-8; DM=-19;
/M: SY='A';  M=  72,  44,  -6, -53, -29,  52,-118, -36,-114,-117,-112,-107,-118,-112,-120, -38, -43, -21,-125, -43; D=-8;
/I:         I=-8; DM=-19;
/M: SY='N';  M= -66,-118,   8, -22,-123,   4, -15,-125, -99, -56,-117, 115,-120,-100, -35,  -2, -98,-125,-138, -34; D=-8;
/I:         I=-8; DM=-19;
/M: SY='P';  M=  45,-125,   2, -58, -42, -69, -30,  -4,   1, -51, -31,  10,  90, -44,-114, -54,-105, -22,-127,-119; D=-8;
/I:         I=-8; DM=-19;
/M: SY='S';  M=   2,-115,  11, -49, -41, -36,-110, -36,-108, -66,-115, -19,-114,-101,-112,  97, -22, -17,-131,-114; D=-8;
/I:         I=-8; DM=-19;
/M: SY='A';  M=  72,-117, -29,  23,  26, -10,-114, -60, -17, -35,-109,-108, -25,  17, -70, -38, -10, -53,-121,-110; D=-8;
/I:         I=-8; DM=-19;
/M: SY='E';  M=-107,-127,  39, 100,-128,  12,-105, -68, -26, -67,-118,-101, -23, -90,-104,-104, -39, -27,-130,-120; D=-8;
/I:         I=-8; DM=-19;
/M: SY='E';  M=  -8,-123,  26,  68,-126,  61,-109,-120,-103, -89, -20, -10,-112, -34, -32, -19, -44,  -1,-128,-120; D=-8;
/I:         I=-8; DM=-19;
/M: SY='G';  M=  36,-123,  11,  35,-127,  57, -17, -37, -72,-121,   7, -23,  33,  25,-112, -28, -66, -64,-126,-119; D=-8;
/I:         I=-8; DM=-19;
/M: SY='D';  M=  -6,  -2,  79,  55,-136,  15,-111,-133,-106,-131,-127, -29, -24,  -8, -72, -36, -55, -55,-140,-125; D=-8;
/I:         I=-8; DM=-19;
/M: SY='D';  M=   8,-144,  47,  47,-147,   2,-127, -43, -36, -71,-137, -32, -70, -36,-127,-121,-127,-137,-151,-139; D=-8;
/I:         I=-8; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='E';  M= -51,-126,  32,  95, -30,   3,-103,-128,   7,-123, -23,  -4,  -3, -89,-101, -45, -57,-123,-126, -31;
/M: SY='G';  M= -34,  23, -25,  19,-125,  78,-112, -44,-107, -67,-116,  25, -18,  -9, -30,   4,  -3, -45,-126,-120;
/M: SY='V';  M=  12,   1, -38,   3, -53,  14,-115, -66, -40, -23,  -4,-107,-117,  22,-113,   6,  38,  57,-125,  -6;
/M: SY='D';  M=  -6,-125,  91,  62,-130, -19,-104,-125, -15,-125, -49, -41,   0, -10,-106, -42, -28, -44,-135,-118;
/M: SY='D';  M=  20,-123,  84,  50,-129,  -5, -31, -63, -56,-125,-120, -20,   3, -98, -43,  20, -26,-119,-134,-118;
/M: SY='T';  M=  28,-116,  16,  -2, -28,  17,  -1,-114, -54, -84, -29,  42, -41, -10,-110,  26,  54, -23,-127, -15;
/M: SY='V';  M=  44,-116, -19,  15,-115, -15,-116, -13, -31, -39,-104,-107,  13, -45,-113,  25,  25,  48,-128,-115;
/M: SY='E';  M= -50,-121, -97,  70,-116, -57,  15,  11,  15,-109,-106,  16,-112,  29, -54, -28,  26,  32,-127, -24;
/M: SY='K';  M= -44,-119, -15, -18, -34,-114,-107, -62,  48, -50,  15, -41, -37,  43,   8,  40,  47,   2,-123, -10;
/I:         I=-13; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='V';  M= -70,-118, -66,-121, -27,  62,-124,   2, -26, -58,-100, -35,-121,-118,-120, -31,-104,  79,-127,-112;
/M: SY='I';  M= -45,  27, -33,-119,-104, -66, -29,  68,-115,   2, -92,  54,-123,-115, -45, -58, -51,  56,-130,-109;
/M: SY='D';  M= -41,-122, 101, -62, -53, -62, -99, -56,-101, -67,-121,  79,-116, -20,-109, -45,  -8,-122,-142,-116;
/M: SY='I';  M= -45,-120, -45, -53,   3, -59,-127,  81,-122,   8, -87,-122,-123, -43,-124, -50,-104,  61,-123,-103;
/M: SY='V';  M= -52,  -8, -54, -36,-102,-128,-127,  31, -68,   2, -91,-120, -29,-119,-121, -25,  -4,  89,-131,-109;
/M: SY='D';  M=-111,-121,  56,  -2,  -6,-122,  55, -29, -49,  46,  17,-105,-120,-106, -20,  -6,   2, -23,-120,  34;
/M: SY='N';  M=  40,-116,  -7, -42,-118,   6, -24,-119, -49, -65,-113,  70,-115,  12, -31,  44,  14,-114,  -3,  11;
/M: SY='H';  M= -69,-120,-111,-112,  88, -45, 100,-108,-111, -28,  10,  41,-123,  10,-110,  -9, -26,-111,-112, -83;
/M: SY='R';  M= -60,-125, -24, -98,-121,  -8,  34,-124,  45, -36,-110,  35,-118,  29,  84,-103,  -8,-121,-124, -29;
/M: SY='L';  M=-115,-118,-130,-124, -37,-132,-112, -83,-124,  91, -32,-129,-131,-117,-121,-123, -51, -90,  30,  45;
/M: SY='Q';  M= -26, -35, -15,  45,-122,-116,  18, -58, -36,-111,-105,   7,-114,  93,-100,  -8,  -9,  43,-128,-111;
/M: SY='E';  M= -28,-125,  18,  90,-126, -65,-105, -34, -13, -54,-115,-102,  25,  17,-102,  27, -49, -68,  -4,-117;
/M: SY='T';  M= -19,  41,-112, -55,-109,-118,-114,  21, -43,  -6,  43, -45, -32, -10,-114,   2,  87, -24,-128, -25;
/M: SY='S';  M= -19,-119, -13, -35,   3,  20,-108, -76, -56,-120,-114,   2,  52,  35,-110,  70,  10, -50,-124, -38;
/M: SY='F';  M=   0, -25, -38,-116,  93, -32, -27, -43, -24,   3,  27,-115,  -1,   6, -23, -41, -39, -62,-102,  23;
/M: SY='D';  M= -49,-121,  71, -31,  19,   5,-108,  15,-108, -36,-109, -58, -19,  -1,-113,  30,  44,-107,-122,  16;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='K';  M= -16,-123, -52, -94, -57,-117, -24, -15, 106, -30,-108, -99,-113, -92, -24, -49, -43, -43,-121,-111;
/M: SY='K';  M= -10,-122, -33,  19,-123, -12,-107,-120,  94, -27,-111,   0, -21, -92, -84,  -6, -31, -60,-123,-115;
/M: SY='S';  M=   2,-119,  56,  43,-121,   7, -29, -67,-103,-118, -10, -97,-112,   7,-109,  58,  -3,   0,-129, -15;
/M: SY='Y';  M= -71,  -6,-124,-124,  77, -67, -98, -22,-118,   5, -95,-121,-130,-117,-116, -39,-112,-102,  17, 112;
/M: SY='M';  M=-106,  -2, -30, -52,-110, -39,-108, -27,  58,   3,  62,-104,-115,  45, -61, -51,  52,   6,-123, -10;
/M: SY='S';  M=  36,-116, -15,  -5,-121, -10,-110, -76,  44, -86,-111, -22, -60,  11,-101,  49,  39,  -2,-127,-115;
/M: SY='Y';  M= -25,-125, -56, -57,  22,-121,  71, -59,-112, -43,  -4, -29,-125,-107,-110, -35, -16,-109,  44, 117;
/M: SY='I';  M= -69,-120,-131,-126,  15,-132,-120,  73,-123,  55,  57, -44, -20,-119,-124,-120,-107,   7,-118,-100;
/M: SY='K';  M=-110,-124,-101, -31,-127,-117,-105,-126, 112,-125,-113, -22,-111,   7, -36,-103, -35,-122,-121,-113;
/M: SY='D';  M=  19,-121,  59,  15,-124,  33,-108,-120,  27, -41,   1, -15,   2, -51, -46,  10,   5, -64,-129,-117;
/M: SY='Y';  M= -59, -17, -53,-120,  19,-124, -90,-104,-114, -50, -99,-118,-129,-110,-112, -33, -28,-109,  42, 132;
/M: SY='M';  M= -26,  11,-127,-121,  -3, -47,-112,  25,-117,  36, 110,-118,-122,-113, -53, -54,   1,   7,-119, -10;
/M: SY='K';  M= -25,-123,-103, -46,-126, -20,-106,-124, 107,-124,-113, -20, -44, -13, -14,-102, -35, -52,-121,-114;
/M: SY='K';  M=  26,-119, -35, -12,-123, -64,-105,-119,  62, -73,-112,  47, -11, -21,  41,  29, -32, -33,-126,-115;
/I:         I=-8; MD=-21;
/M: SY='V';  M= -54,-118,-131,-126, -20,-132,-125,  56,-124,  52, -27,-126,-127,-122,-125, -66, -47,  66,-124,-104; D=-8;
/I:         I=-8; MD=-21;
/M: SY='K';  M= -28,-120, -25, -23,-113,-121,  -4,  -7,  73,  -3,  24,  -9,-117, -19,  -5, -71,   1,  38,-126,-110; D=-8;
/I:         I=-8; MD=-21;
/M: SY='E';  M=  46, -23,  27,  57, -29, -24,-108,-120,  18,-120,-115,   0,  -3,   8,-104,  -5,  -2, -40,-127,-116; D=-8;
/I:         I=-8; MD=-21;
/M: SY='K';  M= -13,-123,-107,-100,-108, -59,  73,-115,  79, -28,  28, -20,-117,  -8,  -4, -45, -27, -55,-116,  52; D=-8;
/I:         I=-8; MD=-21;
/M: SY='L';  M= -67,-119,-130,-123, -92, -48,-117,  23, -20,  80,  43,-126,-128,-116,-119,-121,-110,  -2,  23, -41; D=-8;
/I:         I=-8; MD=-21;
/M: SY='E';  M= -28,-125,  -1,  71,-128,-117,-104,-124,  63,-123,-115, -30,  -3,  46, -48, -18,  14, -57,-126,-116; D=-8;
/I:         I=-8; MD=-21;
/M: SY='E';  M=  23,-124,  16,  84,-128, -67,-105,-126,  34,-124,-117, -35, -15,   6, -54,  -3, -24,-119,   4,-118; D=-8;
/I:         I=-8; MD=-21;
/M: SY='N';  M=  -2,-120,  23,  39,-125,-109,  13,-122,  12, -78,-114,  63,-113,  41, -12,  23,  34,-118,-132,-115; D=-8;
/I:         I=-8; MD=-21;
/M: SY='N';  M= -45, -31,  35, -13, -53,  37,   8,-125,  29, -61, -18,  64,  -1,  31,  14, -31,-106,-124,-129,-115; D=-8;
/I:         I=-8; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='P';  M= -19,-135,  12,  35,-136, -27,-115,-127, -17,-131,-122, -31,  98,  14,-115, -35, -45, -57,-133,-128; D=-8;
/I:         I=-8; DM=-21;
/M: SY='E';  M= -32,-129,  70,  72,-134, -45,-108,-133, -64, -78,-126, -20, -17, -21,-110,  31, -56,-127,-138,-123; D=-8;
/I:         I=-8; DM=-21;
/M: SY='R';  M=  -5,-128,  17,  42,-128,-122,-106,-125,  36, -50,-115, -32,-118,  23,  74,-106, -14, -48,-129,-117; D=-8;
/I:         I=-8; DM=-21;
/M: SY='V';  M=  19, -16,-121, -10,-103,-124,-122,  49,  -5, -15, -16,-118,-121, -40, -52, -61, -54,  73,-125, -10;
/M: SY='K';  M=  43,-121,  43,  49,-127,-111,-107,-121,  61, -78,-114, -43,   1,  11, -95, -39, -11, -65,-127,-117;
/M: SY='E';  M=  42, -16, -18,  44,-122, -19, -11, -39,   5,-114,   1,-104,  36,   3, -44,  -8,  28,   1,-127,-116;
/M: SY='F';  M= -29,-119,-134,-129, 122,-129,-117, -19, -64, -31, -97,-124,-131,-132,-122,-120,-114, -51,  20, -70;
/M: SY='M';  M= -73,-123,-105,   9,-120,-117,-103,-111,  78, -71,  85, -26,  -4,  64, -24, -36, -23, -58,-122,-109;
/M: SY='K';  M=  16,-118,   4,  24,-124,-110,-107,-120,  72,-121,-114,  -7, -40, -31, -92,  42,  41, -66,-127,-115;
/M: SY='G';  M=  -9,-121,  18,   1, -43,  55,-107, -61,  38,-123,-115,  47,-115,  19,  -6, -15, -13, -33,-126,-116;
/M: SY='A';  M=  78,  29,-119,-114, -53, -39,-118,   5,-114, -23,  54,-112,-117,-111,-117, -35,  10,  17,-125,-112;
/M: SY='Q';  M=  17,-121,-105,   1,-125,  -6,-106,-115,  14,-116,  26, -57,  42,  82,-100,  34,  14, -35,-124,-114;
/M: SY='A';  M=  46,-119,  23,  43,-123,   4,-109, -61,  42, -33,-112, -21, -19, -40, -62,   7,   1, -54,-126,-117;
/M: SY='F';  M=  29, -39,-121, -56,  66, -21, -18, -48, -33, -12,  31,-115, -51,  41, -58,-108, -66,  -3,  64,  51;
/M: SY='V';  M=   5, -18,-127,-122,  16,-125,-122,  34,-119,  10,  58, -39, -24,-118,-121, -47, -25,  71,-124,-103;
/M: SY='K';  M=-108,-123,-103, -51,-124, -27,-106,-121, 107,-122,  10, -27, -17, -90, -46,  -5, -35, -48,-122,-113;
/M: SY='W';  M= -52,-125,  28,  19,  -2, -32,  53,-119,  51, -55,  13, -35, -31,  -2, -29,   3,   5,-118,  81,  16;
/M: SY='I';  M=-109, -24, -68,-121,  -1,-130, -10,  58, -28,  43,  21,-121,-124, -23,-119, -34, -47,  50,  42,-100;
/M: SY='L';  M= -53,  -7,-126,-119,  -6,-127,-116,  17, -19,  72,   7,-121, -49, -36,-117,   2, -42,  22,-119, -24;
/M: SY='G';  M=  36,-120, -13,  34, -27,  49,-110, -65,  40, -21,-111, -20, -22, -19,-103,   3,-105, -59,-123,-115;
/M: SY='N';  M= -40,-120,  29, -29,-124, -18,-100,-120,  54, -78,  -1,  85, -60, -55,  23,   8, -50, -39,-131,-115;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='F';  M= -34,-121, -59,-125, 109,-126, -17, -17, -72, -13, -98, -27,-130,-125,-120, -53, -39, -62,  27,  51; D=-36;
/I:         I=-36; DM=-90;
/M: SY='K';  M= -68,-125,  73,   9, -65, -26,   2,-127,  81, -74,-118,  11, -31, -94, -51, -13,-104,-124,-129,-114;
/M: SY='D';  M= -43,-124,  88,  46, -24,-111,-100,-126,  15,-126,-120,  62,-113,   7,-102, -36, -50, -65,-136,-115;
/M: SY='Y';  M=-115,   9,-125,-123,  32,-127, -26,   4,-118,  41,  24,-122, -48,-115,-117, -21,-111, -32,  62,  99;
/M: SY='Q';  M=-106,-127,  45,  53,-130, -63,-101,-126,  -5,-122,-114, -96,-111,  99, -19,  18,  -5,-123,  28,-112;
/I:         I=-45; MD=-115;
/M: SY='F';  M=-119,-119,-133,-129, 117,-130, -44, -18,-125, -69, -16,-123, -63,-132,-123,-119, -19,   8, -94,  12; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='Y';  M=-120,-125,-125,-124,  90,-127, -37,-100,-118, -35, -16,-121,-131,-118,-115, -59,-114,-105,  31, 114;
/M: SY='M';  M= -28,  -2,-118,-114,-106,-121, -46,  39,-111, -26,  79,-109,-117,  23, -58, -10,  66,  40,-128,-107;
/M: SY='G';  M= -98,-123,-111,-119, -43,  99,  -8,-133,-114,-130,-120, -98,  12,-112, -47,  13, -22,-127,-122,-121;
/M: SY='E';  M=  -4,-124, -89,  95,-126,-117,-105, -65,  18, -35,-114, -27,  25, -35,-100,  13, -25,-117,-127,-118;
/M: SY='S';  M= -96,-115,  -4, -64,-123,  12,  -9,-121, -33,-125,-117,  61,-114, -12,-107,  91, -32, -38,-132,-115;
/M: SY='M';  M= -67,  25,  -3, -64,  40, -75,-105, -29, -36, -11, 121, -15,-121, -21, -69, -16, -23, -54,-115,  17;
/M: SY='D';  M= -20,-121,  85,   4,-122, -18,   8,-122, -27,-125,-119,  76,-116,-100,-107, -10, -27, -28,-135,   5;
/M: SY='P';  M=  -1,  -4,  20,  28, -36, -14,-113, -16,-108, -67, -17, -46,  82, -40,-115,   0,  15,   6,-127, -32;
/I:         I=-11; MI=0; MD=-28; IM=0; DM=-28;
/M: SY='D';  M= -35,-126,  89,  61,-131, -49,-102, -65,   1,-127,-123,  33, -45, -95, -31, -21, -23,-124,-137,-119; D=-11;
/I:         I=-11; DM=-28;
/M: SY='G';  M=  33,  40,-113,-118, -55,  89,-117, -64,-115,-126,-118, -14,-117, -13,-121, -24, -53,-120,-124,-122; D=-11;
/I:         I=-11; DM=-28;
/M: SY='M';  M= -10, -30,-120,-114, -14,   4,  11,   6,-110,   0, 116, -47,-119,  29, -29,  -3, -20, -96,-120, -16;
/M: SY='V';  M= -72,-119,-125, -38, -98,-129,  12,  47,-118,  20,  49,-120, -12, -13,-119,-114, -22,  69,  -1,  13;
/M: SY='A';  M=  66,  27,-123,-118, -22,  -2,-123,  38,-117, -22, -18,-116, -61,-116,-121,-102,-103,  51,-125,-111;
/M: SY='L';  M= -77,-119,-128,-124,  51,-130,-112,  15,-122,  72,  29, -27, -27,-119,-121,-120, -53, -30,-108,  36;
/M: SY='M';  M=  13,  48, -24,-116, -50,  -1,-115,  -6,-117,  52,  60,-113,-123, -22,-118,  28,-104,   1,-124,-107;
/M: SY='Y';  M=-111,-124,  54,  18, -48, -32, -25, -51,  12,-115, -33,  64,-118,-100, -24, -37, -22, -29,  13,  80;
/M: SY='Y';  M=-118,  -3, -51,-119,  42,-124,   6,-106,-113, -46,-100, -38,-129, -27, -54, -55,-114,-111,  90, 122;
/I:         I=-31; MD=-79;
/M: SY='R';  M=-114,-131, -15,  14,-128, -38,  34,-131,  45,-125,  -1, -27, -39, -94,  87, -20, -41,-126,-130,-114; D=-31;
/I:         I=-31; MD=-79;
/M: SY='E';  M=-116,-136,  54,  88,-139,  -9,-112,-136, -68, -78,-129,-107, -63, -18,-112, -60, -56, -55,-140,-128; D=-31;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='D';  M= -74,-127,  96,  47,-133,  52,-105,-133, -70,-130,-125, -53,-112, -18,-110, -56, -51,-128,-135,-120;
/M: SY='G';  M=   5,-124,  44,  37,-130,  75,-109,-131, -63,-128,-120, -11, -14,   3, -27, -36, -51,-125,-127,-121;
/M: SY='V';  M= -11,-119,   2,  45,-112,-119, -17,  25,-105, -39,   7,   5,-116,  10, -18,   4,  12,  54,-130,-111;
/M: SY='T';  M= -46, -14,   2, -27, -44, -36,-112, -30,  -5,-111,-107,  -9,-112, -19, -13,  15,  93,  14,-132,-112;
/M: SY='P';  M= -33,-135,-115, -58,-128,-116,-118,   8,-111,-123,-113,-119, 126, -47,-122, -58, -35,-116,-126,-127;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='Y';  M= -57,  19,-117,-114,  34,-123, -15, -21,  -6, -24, -25,-111,-122,  -7, -12, -55,  55,  13,-101,  91;
/M: SY='M';  M=  -6, -10,-131,-124,  89, -67,-112, -30,-121,  17, 102,-121,-126,-119,-119,-117,-109,  -2,-106, -85;
/M: SY='Y';  M= -57, -16,-123,-120, -22,-126,-111,  47,-117,  14,  51,-117,-123, -20,-118, -26,  32,  37, -21,  71;
/M: SY='F';  M= -60,-120,-129,-126, 103, -54,-108, -35, -72,  -1,   4,-122,-130,-124,-119, -60,-111,  -1, -91,  75;
/M: SY='W';  M=-119,-125, -69,-128,  93,-129,-123,  36,-124,  19, -17,-128, -52,-126,-124,-123,-116, -43, 119, -34;
/M: SY='K';  M=   3,-122,-104, -50,-123,-115, -24, -29, 108, -66,-110, -98,-111, -90, -77, -29, -55, -65,-121,-112;
/M: SY='H';  M=   6,-125,  91,  -6, -38,-113,  92,-124,-103, -77,   1, -18,-115, -25, -63, -29, -38,-122,   7,  -4;
/M: SY='G';  M=  -1,  15,-113,-121,-125,  99,-117, -36,-116,-127,-119,-100,-116,-113,-123, -10, -64,-122,-121, -18;
/M: SY='L';  M=-111,-116,-128, -60, -52,-130,-115, -36,-121,  85,  37,-126,-128,-116, -67, -35, -32,  16,-119, -27;
/M: SY='K';  M= -68,-122, -40,  32,-115,-120,-109,  24,  78, -16,-103,  -6,-114, -23,  -6, -28, -20,  17,-123, -47;
/M: SY='E';  M= -17,-124, -47,  87, -63,  -6,-105, -52,  -4, -72,  50,-104, -22,  28, -31, -15,  -8, -35,-125,-115;
/M: SY='E';  M=-106,-124, -22,  95,-119, -18,-106,   3, -97, -53,  35, -30,-109,   9,-105, -40, -37,  17,-127, -49;
/M: SY='K';  M=-110,-124, -35, -32,-124,-118, -28,-121, 109, -73,   1, -43,-112, -89,   3, -66, -64, -45,-121,-112;
/M: SY='C';  M= -33, 104,-124, -70,  41,-125,-115, -30, -73, -18, -17,-118, -51,  23,-118, -68,-106,  52,-114,  52;
/I:         E1=0; IE=-380; DE=-380;

» more

Post-processing [info]

COMPETES_HIT_WITH

PS51796

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.

Total number of hits	89 in 89 different sequences
Number of true positive hits	89 in 89 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	TCTP
Version [info]	3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

89 sequences

NF40_NAEFO  (P83728), TCTP1_ARATH (P31265), TCTP1_DICDI (Q54RX6),

TCTP2_ARATH (Q9M9V9), TCTP2_DICDI (Q54RX1), TCTP8_HUMAN (Q9HAU6), 
TCTP_AEDAE  (Q1HR79), TCTP_AEDAL  (Q5MIP6), TCTP_ALTAL  (D0MQ50), 
TCTP_ANOGA  (Q7QCK2), TCTP_ASPFU  (Q4WRB8), TCTP_ASPOR  (Q2UR29), 
TCTP_BOMMO  (Q75VN3), TCTP_BOVIN  (Q5E984), TCTP_BRABE  (Q95VY2), 
TCTP_BRAOL  (Q944W6), TCTP_BRUMA  (P90697), TCTP_CAEBR  (Q622B7), 
TCTP_CAEEL  (Q93573), TCTP_CANAL  (Q5A860), TCTP_CANGA  (Q6FKB6), 
TCTP_CHICK  (P43347), TCTP_CROAD  (J3SFJ3), TCTP_CROHD  (T1DKS4), 
TCTP_CRYNB  (P0CR83), TCTP_CRYNJ  (P0CR82), TCTP_CUCMA  (Q2PS27), 
TCTP_CUCME  (Q9M5I8), TCTP_DANRE  (Q9DGK4), TCTP_DAVTA  (A1KXP4), 
TCTP_DEBHA  (Q6BP09), TCTP_DROME  (Q9VGS2), TCTP_DROPS  (Q293Y0), 
TCTP_DROYA  (Q6XIN1), TCTP_ELAGV  (Q5J907), TCTP_EMENI  (Q5BFN9), 
TCTP_FRAAN  (O03992), TCTP_GIBZE  (Q4IJT5), TCTP_GRARO  (M5B4R7), 
TCTP_HEVBR  (Q9ZSW9), TCTP_HORVU  (Q9M5G3), TCTP_HUMAN  (P13693), 
TCTP_HYDVU  (Q94587), TCTP_IXOSC  (Q4PLZ3), TCTP_KLULA  (Q6CTH3), 
TCTP_LABRO  (Q98SJ7), TCTP_LATJA  (Q6XSH4), TCTP_LONON  (Q5MGM6), 
TCTP_LOXIN  (G3LU44), TCTP_LUMRU  (O18477), TCTP_MAIZE  (Q8H6A5), 
TCTP_MEDSA  (P28014), TCTP_MICFL  (U3EQ60), TCTP_MOUSE  (P63028), 
TCTP_MYCMD  (Q4PF30), TCTP_NEUCR  (Q7RYV5), TCTP_ORYSJ  (P35681), 
TCTP_PANTR  (A5A6K2), TCTP_PEA(P50906), TCTP_PIG(P61288), 
TCTP_PLABA  (Q4YZC6), TCTP_PLACU  (Q4XFJ8), TCTP_PLAF7  (Q8I3Z5), 
TCTP_PLAKN  (P84152), TCTP_PLAYO  (Q9XYU2), TCTP_PLUXY  (Q60FS1), 
TCTP_PSEMZ  (Q9ZRX0), TCTP_RABIT  (P43348), TCTP_RAT(P63029), 
TCTP_SCHHA  (Q8I8A2), TCTP_SCHJA  (P91800), TCTP_SCHMA  (Q95WA2), 
TCTP_SCHPO  (Q10344), TCTP_SCOMX  (Q202I6), TCTP_SOLLC  (Q6DUX3), 
TCTP_SOLTU  (P43349), TCTP_SOYBN  (Q944T2), TCTP_THEAN  (Q4UGL5), 
TCTP_THEPA  (Q4N938), TCTP_TOBAC  (Q9XHL7), TCTP_TRIPS  (Q2L875), 
TCTP_TRYBB  (P35758), TCTP_WHEAT  (Q8LRM8), TCTP_WUCBA  (Q962A2), 
TCTP_XENLA  (Q7ZYF2), TCTP_XENTR  (Q66JC5), TCTP_YARLI  (Q6C4G1), 
TCTP_YEAST  (P35691), TPT1L_HUMAN (Q56UQ5)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

15 PDB

1H6Q; 1H7Y; 1TXJ; 1YZ1; 2HR9; 2KWB; 2LOY; 3EBM; 3P3K; 4Z9V; 5O9K; 5O9L;
» more