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PROSITE entry PS51733


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51733
Entry name [info] BPL_LPL_CATALYTIC
Accession [info] PS51733
Entry type [info] MATRIX
Date [info] 01-SEP-2014 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51733
Associated ProRule [info] PRU01067

Name and characterization of the entry

Description [info] Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) catalytic domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=183;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=178;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8220429; R2=0.0094802; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=27061.7480469; R2=8.7651453; PRIORITY=1; TEXT='Heuristic 0.1%';
/CUT_OFF: LEVEL=0; SCORE=758; H_SCORE=33706; N_SCORE=9.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=494; H_SCORE=31392; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-16; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 580 in 580 different sequences
Number of true positive hits 580 in 580 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.66 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] BPL/LPL catalytic
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
580 sequences

BICOA_NEIG1 (Q5F5C8), BICOA_NEIMA (Q9JWI7), BICOA_NEIMB (Q9JXF1), 
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UniProtKB/Swiss-Prot
False negative sequences
2 sequences

BIRA_MYCTU  (I6YFP0), LIPLB_PLAF7 (Q8I2S0)

		
PDB
[Detailed view]
44 PDB

1BIA; 1BIB; 1HXD; 1W66; 1X2G; 1X2H; 2ARS; 2ART; 2ARU; 2C7I; 2C8M; 2CGH;
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