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PROSITE entry PS51687


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51687
Entry name [info] SAM_MT_RNA_M5U
Accession [info] PS51687
Entry type [info] MATRIX
Date [info] 01-AUG-2013 CREATED;
01-AUG-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51555
Associated ProRule [info] PRU01024

Name and characterization of the entry

Description [info] SAM-dependent methyltransferase RNA m(5)U-type domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=362;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=357;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3073914; R2=0.0060911; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=2084; N_SCORE=15.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=689; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-27; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 570 in 570 different sequences
Number of true positive hits 570 in 570 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] SAM-dependent MTase RNA m(5)U-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
570 sequences

ARLMC_PYRAB (Q9UZK1), ARLMC_PYRFU (Q8U2K7), ARLMC_PYRHO (O58994), 
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PDB
[Detailed view]
12 PDB

1UWV; 2BH2; 2JJQ; 2VS1; 3BT7; 5XJ1; 5XJ2; 5ZQ0; 5ZQ1; 5ZQ8; 5ZTH; 8Z62