PROSITE entry PS51670
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General information about the entry
| Entry name [info] | SHKT |
| Accession [info] | PS51670 |
| Entry type [info] | MATRIX |
| Date [info] |
01-MAR-2013 CREATED;
01-MAR-2013 DATA UPDATE; 27-MAR-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51670 |
| Associated ProRule [info] | PRU01005 |
Name and characterization of the entry
| Description [info] | ShKT domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=35; /DISJOINT: DEFINITION=PROTECT; N1=1; N2=35; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.4714091; R2=0.0058477; TEXT='NScore'; /CUT_OFF: LEVEL=0; SCORE=689; N_SCORE=7.5; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=518; N_SCORE=6.5; MODE=1; TEXT='RR'; /DEFAULT: M0=-50; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='C'; M= -91, 158,-111,-111,-101,-107,-111,-108,-107, -99, -99, -97,-122,-115,-113, -94, -91, -96,-131,-112; /M: SY='K'; M= -14, -26, 0, 36, -45, -72, -34, -24, 36, 8, -32, -40, -17, 7, 24, 2, 35, -45,-106, -20; /I: I=-28; MD=-71; /M: SY='H'; M=-117,-129, 20, -35, -67,-122, 80, -29, -59, -96,-108, -2,-123, -25, -23, -50,-112, -23,-120, 51; D=-28; /I: I=-28; MD=-71; /M: SY='E'; M=-111,-127, -91, 68,-123,-120, -47,-125, -23,-125,-119, 30, -61, -60,-105, -18, -19, -45,-128, 4; D=-28; /I: I=-28; MI=-71; IM=-71; DM=-71; /M: SY='D'; M= -54,-105, 104, -70, -27, -90, -80, -57, -83, -72,-105, 84,-100, -84, -92, -82, -84,-107,-126, -98; /M: SY='K'; M= -25,-106, 16, 9, -99,-101, -6, -52, 57, 8, -29, -52, 20, 19, 28, -25, 7, -11, -7, -48; /I: I=-26; MD=-65; /M: SY='F'; M= -1,-105, -57,-101, 78, -51, 33, -11, -24, -21, -85, 9,-110, -97, -18, -15, -35, -71, -84, 69; D=-26; /I: I=-26; MD=-65; /M: SY='T'; M= -30,-100, -29, -53, -4, -66, -16, -2, -8, -72, -18, 12, -17, -91, -95, 44, 76, -14,-113, -48; D=-26; /I: I=-26; MI=-65; MD=-65; IM=-65; DM=-65; /M: SY='N'; M= -47, 14, 26, -15, -62, -90, -10, -10, -38, -69, -34, 98,-103, -40, -30, 8, -26, -31, 34, -29; D=-26; /I: I=-26; DM=-65; /M: SY='C'; M= -91, 158,-111,-111,-101,-107,-111,-108,-107, -99, -99, -97,-122,-115,-113, -94, -91, -96,-131,-112; /M: SY='P'; M= 1,-109, 29, -2,-111, 4, -94,-106, 34, -81,-102, 32, 49, -35, -29, -8, 14, -44, 17,-103; /M: SY='D'; M= 2,-106, 47, -45, -18, -52, 29, -19, -29, -43, -11, -11, -36, -6, -8, 43, 5, -25, -16, 3; /M: SY='W'; M= -65,-110,-114, -62, 0,-112,-104, -27, -32, 58, 22, -9,-113, -50,-103, -66, -61, -36, 119, 14; /M: SY='A'; M= 46,-102, -99, -24,-101, -99,-101, -10, 33, -38, -89, -93,-102, -16, 13, -6, 19, 37,-112, -99; /I: I=-15; MD=-39; /M: SY='K'; M= -9,-112, -32, -25, -59, -28, -12,-108, 50, -41,-100, -2, -52, 41, 21, 19, -12, -48,-114, -42; D=-15; /I: I=-15; MD=-39; /M: SY='Q'; M= -55,-113, -65, -11, -20, -52, -38, -32, 5, -17, -20, 14,-107, 75, 20, 5, 3, -64,-111, -24; D=-15; /I: I=-15; MD=-39; /M: SY='G'; M= -37,-120, -23,-110, -64, 48, -65, -75, -56, -40,-111, 23,-117, -14, -33, 13, -53, -14,-125, -60; D=-15; /I: I=-15; MD=-39; /M: SY='M'; M= -78,-121, -57, 1, 13, 19, -13,-111, -5, -9, 20, 4,-118, -47,-108, 10, -41,-112, -15, -29; D=-15; /I: I=-15; MI=0; MD=-39; IM=0; DM=-39; /M: SY='C'; M= -99, 150,-119,-119,-109,-114,-119,-116,-115,-107,-107,-105,-130,-122,-121,-101, -99,-103,-139,-120; /M: SY='Q'; M= -97,-115, -18, 12, -58, -15, 20, -69, 26, -80, -57, 36,-104, 74, 21, -18, -13,-111,-116,-100; /I: I=-20; MI=0; MD=-50; IM=0; DM=-50; /M: SY='H'; M= -69,-114, 48, -47, -52,-108, 51,-102, -10, -77, 38, -38, 13, -52, -45, 11, 26, -6,-125, -29; D=-20; /I: I=-20; DM=-50; /M: SY='E'; M= -88,-118, 14, 41, -63, -49, -97,-115, 37, -82,-108, 21, 22, 17, -19, 12, -68, -45,-121,-109; D=-20; /I: I=-20; DM=-50; /M: SY='W'; M= -72,-117,-107,-100, 18, -50, 30, -97, -7, 2, -91, -46,-113, 39, -31, -44, -14, -68, 98, 72; /I: I=-22; MI=0; MD=-57; IM=0; DM=-57; /M: SY='M'; M= -66,-109, -75,-109, -42,-116, -99, 26, -40, 5, 109,-108, -52, -99, -4,-106, -47, 15,-109, 1; /M: SY='K'; M= -6,-111, -47, -54, -37,-105, -34, -35, 59, -33, -12, 5, -57, 28, 26, -16, 12, -73,-111, -19; /M: SY='S'; M= 6, -32, -36, 29, -55,-100, -33, -62, 13, -47, -34, -5,-102, 0, -8, 47, 26, -37,-117,-103; /M: SY='N'; M= -79,-110, -1, -65, 22, -55, -16, -49, 18, -9, -97, 78,-110, 1, -20, -3, -92,-104, -1, 11; /M: SY='C'; M= -99, 150,-119,-119,-109,-114,-119,-116,-115,-107,-107,-105,-130,-122,-121,-101, -99,-103,-139,-120; /M: SY='P'; M= 26,-116,-101, -60,-118, -38,-101,-112, 33, -66, -40, -98, 71, 22, 30, -12, -96,-108,-115,-109; /M: SY='A'; M= 61,-107,-101, -56, -36, -99,-103, -40, 58, -51, -99, -55,-106, -90, 4, -13, -68, -63,-113,-104; /M: SY='T'; M= -36,-102, -97, -98, -56, -98,-103, -58, -97,-106,-102, -86,-101, -95,-103, 68, 86, -95,-123,-104; /M: SY='C'; M=-100, 149,-120,-120,-110,-116,-120,-117,-116,-108,-108,-106,-131,-124,-122,-103,-100,-105,-140,-121; /I: I=-24; MD=-61; /M: SY='G'; M=-115,-134, -21, -63, -17, 49, -40,-140, -19,-137,-128, 32,-128, -28, -26,-109,-119,-137,-134,-124; D=-24; /I: I=-24; MI=0; MD=-61; IM=0; DM=-61; /M: SY='F'; M= -70,-111, -61,-104, 68, -65, -37, -58, 20, 20, -5, -57,-115, -1, -23, -15, 7, -62, -13, -34; /M: SY='C'; M=-102, 147,-122,-122,-112,-118,-122,-119,-118,-110,-110,-108,-133,-126,-124,-105,-102,-107,-142,-123; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 136 in 120 different sequences |
| Number of true positive hits | 136 in 120 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 10 |
| Number of 'partial' sequences | 2 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 93.15 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 4 |
| Feature key [info] | DOMAIN |
| Feature description [info] | ShKT |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
120 sequences
1AK_HETMG (O16846), AURE_AURAU (Q0MWV8), CRIS1_HUMAN (P54107), CRIS1_MACMU (Q9XSD3), CRIS1_MOUSE (Q03401), CRIS1_RAT (P12020), CRIS2_CAVPO (Q60477), CRIS2_HUMAN (P16562), CRIS2_MOUSE (P16563), CRIS3_HORSE (O19010), CRIS3_HUMAN (P54108), CRIS3_MOUSE (Q03402), CRIS_PROFL (P0CB15), CRVP1_DISTY (Q2XXQ6), CRVP1_HYDHA (Q8UW25), CRVP1_NAJAT (Q7T1K6), CRVP1_NAJKA (P84805), CRVP1_PSEPL (Q2XXQ3), CRVP2_DISTY (Q2XXQ5), CRVP2_HYDHA (Q8UW11), CRVP2_NAJAT (Q7ZZN8), CRVP2_NAJKA (P84808), CRVP2_PSEPL (Q2XXQ2), CRVP3_DISTY (Q2XXQ4), CRVP5_VARAC (Q2XXR0), CRVPA_VARVA (Q2XXP2), CRVPB_VARVA (Q2XXP1), CRVP_AGKPI (Q7ZTA0), CRVP_AUSSU (A8S6B6), CRVP_CAURH (A7X4T8), CRVP_CERRY (D8VNS1), CRVP_CROAD (F8S0Y4), CRVP_CROAT (Q7ZT99), CRVP_DEMVE (A6MFK9), CRVP_DRYCN (F8J2D4), CRVP_ECHCO (P0DMT4), CRVP_ERYPO (Q2XXQ0), CRVP_GLOBL (Q8JI40), CRVP_HELHO (Q91055), CRVP_HOPST (Q3SB03), CRVP_LATSE (Q8JI38), CRVP_LEIMD (Q2XXQ1), CRVP_NOTSC (Q3SB04), CRVP_OPHHA (Q7ZT98), CRVP_OXYMI (Q3SB06), CRVP_OXYSC (Q3SB07), CRVP_PHIOL (Q09GJ9), CRVP_PROFL (Q8JI39), CRVP_PROJR (Q7ZZN9), CRVP_PROMU (P79845), CRVP_PSEAU (Q8AVA4), CRVP_PSEPO (Q8AVA3), CRVP_PSETE (Q3SB05), CRVP_RHATT (Q8JGT9), CRVP_SISCA (B0VXV6), CRVP_TELDH (Q2XXP5), CRVP_TRIBI (Q2XXP4), CRVP_TRIST (P60623), CRVP_VIPBE (B7FDI1), CRVP_VIPBN (B7FDI0), CUE3_CONIM (P0DUB0), K1A_ANEER (Q0EAE5), K1A_CRYAD (E2S064), K1A_HETHE (E2S065), K1A_STIGI (E2S061), K1A_STIHA (E2S062), K1A_STIHL (P29187), K1A_STIME (E2S063), K1A_THAAS (E2S066), K1B1_BUNCI (C0HJC2), K1B1_OULSP (A0A330KW27), K1B2_BUNCI (C0HJC3), K1B2_OULSP (A0A330KUG5), K1B9A_ANEVI (P0DN00), K1B9C_ANEVI (P0DN02), K1B9D_ANEVI (P0DN03), K1BAA_ANEVI (P0DN04), K1BBA_ANEVI (P0DN05), K1B_ACTEQ (P81897), K1B_ANESU (Q9TWG1), K1B_BUNGR (P29186), K1B_METSE (P11495), MAB7_CAEEL (Q95Q39), MFAP2_BOVIN (P27424), MFAP2_HUMAN (P55001), MFAP2_MOUSE (P55002), MLT7_CAEEL (Q23490), MMP23_BOVIN (Q2TBM7), MMP23_HUMAN (O75900), MMP23_MOUSE (O88676), MMP23_RAT (O88272), NAS10_CAEEL (Q21388), NAS11_CAEEL (Q21432), NAS12_CAEEL (Q9XTD6), NAS13_CAEEL (Q20191), NAS14_CAEEL (Q19269), NAS15_CAEEL (P55115), NAS31_CAEEL (Q7JLI1), NAS32_CAEEL (O16977), NAS6_CAEEL (Q9U3S9), NAS7_CAEEL (P55113), NAS8_CAEEL (Q18439), NAS8_STECR (D2KBH9), NAS9_CAEEL (P91137), NEP4_NEMVE (A7RNZ0), NEP8_NEMVE (A7SXG9), P4H12_ARATH (Q8GXT7), P4H2_ARATH (F4JAU3), P4H4_ARATH (Q8LAN3), P4H7_ARATH (Q8L970), SKPO1_CAEEL (Q20616), SRGT1_CHLRE (H3JU05), SURO1_CAEEL (Q9XU75), TES26_TOXCA (P54190), TYR1_CAEEL (P34269), TYR3_CAEEL (Q19673), YOFA_CAEEL (Q09337), YOW6_CAEEL (P30652), YP95_CAEEL (Q09244), YS51_CAEEL (Q09662)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
10 sequences
CL8L_NEMVE (P0DQR8), K1B9B_ANEVI (P0DN01), K1HH_ANESU (P0DPF1), NEP3L_NEMVE (A7RJ13), NEP3_NEMVE (A7RJ12), P4H6_ARATH (F4J0A8), SHKL1_NEMVE (P0DQR6), SHKL2_NEMVE (A7SRR3), SHKL4_NEMVE (A7ST80), TX8E_ANEVI (P0DMZ7)» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
2 sequences
CRVP_BOTCO (P0DMG5), CRVP_BOTFO (P0DMG6) |
| PDB [Detailed view] |
29 PDB
1BEI; 1BGK; 1RC9; 1ROO; 1WVR; 1XTA; 1XX5; 2A05; 2CQ7; 2DDA; 2DDB; 2EPF; 2GIZ; 2K72; 2K9E; 2LG4; 3MZ8; 4LFQ; 4LFS; 4Z7P; 5I5A; 5I5B; 5I5C; 5WCV; 6BUC; 6CKD; 6CKF; 6IMF; 7OD2 » more |