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PROSITE entry PS51403


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General information about the entry

Entry name [info] NC1_IV
Accession [info] PS51403
Entry type [info] MATRIX
Date [info] 01-AUG-2008 CREATED;
10-MAY-2017 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51403
Associated ProRule [info] PRU00736

Name and characterization of the entry

Description [info] Collagen IV carboxyl-terminal non-collagenous (NC1) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=224;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=219;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=4.0225711; R2=0.0080653; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-9033.5957031; R2=20.7676735; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=556; H_SCORE=2513; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=308; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-56; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='G';  M= -63, -88, -76, -88, -91,  86, -82, -95, -82, -31, -83,  -8, -82, -79, -88, -63, -79, -92, -87, -88;
/M: SY='F';  M= -85, -85, -97, -94,  95, -95, -22,  -3, -89, -26, -60, -88, -97, -94, -87, -85, -78, -22, -56,  35;
/M: SY='L';  M= -20, -82, -91, -87,  -7, -92, -79,   6, -85,  47, -50, -87, -91, -82, -85, -78,   5,  14, -78,  30;
/M: SY='F';  M= -81, -85, -97, -91,  68, -98, -83,  24, -85,  38, -52, -90, -95, -87,  -8, -86, -76, -20, -71, -51;
/M: SY='T';  M=   5, -76, -79, -78, -74, -83,  20, -50, -76, -64, -63, -71, -80, -78, -81, -60,  63,  56, -99, -74;
/M: SY='R';  M= -76, -90, -76, -65, -75, -88, -68, -73,  46, -12, -10, -70, -85, -58,  72, -74, -73,  -7, -82,   9;
/M: SY='H';  M= -79, -92, -64, -63, -79, -81, 135, -96, -67, -79, -65, -54, -80,   9, -62, -69, -78, -96,-111, -49;
/M: SY='S';  M= -53, -75, -67, -68, -15, -62, -70, -82, -68, -85, -80, -56, -75, -61, -73,  93,   0, -75, -90, -73;
/M: SY='Q';  M= -70, -96, -66, -45,-100, -78, -59, -86, -51, -82, -69, -62,   3, 118, -52, -60, -72, -88, -83, -72;
/M: SY='T';  M= -43, -74, -15, -69,  -2, -73, -74, -74, -68, -77, -74, -34, -73, -69, -39,  46,  81, -67, -92, -72;
/M: SY='T';  M= -67, -80,  41,  14, -80, -81, -75, -17, -66, -72, -71, -61, -75, -67, -17, -16,  65,  19, -99, -77;
/M: SY='Q';  M=   6, -84, -21,  34, -82,  -6,  16, -78, -25, -79, -73,   2, -76,  44, -29, -41,  10, -11, -87,   1;
/M: SY='V';  M= -47, -85, -40,  20, -72, -30, -83,  44, -76, -51, -60,   3,  29, -74, -82, -73, -66,  45, -92, -76;
/M: SY='P';  M= -77,-101, -78, -67, -92, -80, -80, -80, -74, -30, -77, -84, 114, -77, -86, -75, -70, -86, -89, -92;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='Q';  M= -33, -81, -26,  29, -84, -73, -43, -77, -59, -54,  12, -60, -19,  56, -17,  43,  35, -57, -89, -74;
/M: SY='C';  M= -71, 144, -91, -91, -81, -86, -91, -88, -87, -79, -79, -77,-102, -94, -93, -73, -71, -75,-111, -92;
/M: SY='P';  M= -54, -99, -74, -18, -95, -77, -78, -83, -71, -93, -79, -81, 115, -73, -83, -47, -68, -87, -88, -92;
/M: SY='P';  M=  35, -82, -45,  34, -70, -16, -45,  -6, -67, -33,  25, -11,  40,  -5, -61, -44, -52, -38, -87, -77;
/M: SY='G';  M= -62, -84,  14, -18, -85,  75, -72, -92, -72, -90, -82,  18, -77, -70, -79, -34,   3, -87, -84,  -6;
/M: SY='M';  M= -17, -75, -72, -71, -63, -76,  30, -62, -68, -39,  74, -63, -74, -31, -48,   3,  69, -61, -79,  36;
/M: SY='N';  M= -38, -79,   7, -43, -76, -74, -68, -34, -22,  -1, -65,  37,  29,   4, -13,  10,  32,  -3, -91, -74;
/M: SY='K';  M= -73, -87, -70, -22,  13, -81, -46, -46,  49, -17,   3, -66,  35,  40,  40, -68, -34, -74, -78, -66;
/M: SY='L';  M= -73, -78, -91, -84, -51, -93,  12, -10, -84,  73,  10, -88, -90, -78, -82, -83, -70,   9, -82, -61;
/M: SY='W';  M= -81,-100, -94, -81,   6, -83, -78, -75, -22, -72, -72, -90, -87,  -3, -75, -82, -85, -85, 149,  69;
/M: SY='T';  M= -65, -79,  46,  31, -53, -76,   3, -67, -63, -32, -39,  -7, -73, -62, -40,   6,  49,  11, -96, -73;
/M: SY='G';  M= -60, -87, -75, -86, -90,  91, -81, -96, -80, -41, -82, -61, -79, -78, -87, -60, -78, -91, -84, -87;
/M: SY='Y';  M= -82, -44, -82, -84,  31, -89, -51, -67, -74, -62, -61, -82, -94, -73, -17, -77, -76, -71, -40, 116;
/M: SY='S';  M= -51, -74, -66, -67, -84, -59, -69, -84, -67, -88, -81, -54, -74, -59, -71,  98, -46, -76, -93, -76;
/I:         I=-30; MD=-77;
/M: SY='L';  M= -80, -84, -95, -88, -11, -97, -77, -27, -88,  68, -45, -94, -12, -83, -86, -88, -76, -37, -75,  31; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='L';  M= -46, -80, -94, -87, -56, -94, -82, -44, -88,  70, -44, -92, -94, -82, -86, -27, -72,  13, -86, -67;
/M: SY='Y';  M= -79, -89, -84, -83,  43, -17, -59, -67, -78, -62,  41, -79, -91,  -8, -77, -38, -20, -71, -51,  95;
/M: SY='V';  M= -43, -81, -87, -87, -16,   0, -86,   2, -84,  20, -37,   2, -90, -83, -86, -47, -67,  57, -90, -71;
/M: SY='Q';  M= -70, -91,   5,  45, -93,   1, -67, -42, -59, -81, -24, -28, -76,  78, -64, -64,  -5, -30, -90, -79;
/M: SY='G';  M= -25, -88, -77, -87, -95,  89, -83,-101, -82, -97, -87, -63, -80, -79, -89, -61, -79, -94, -86, -90;
/M: SY='N';  M= -29, -82, -11, -61, -86, -68,  34, -76, -60, -82, -72,  84, -54,  58, -64, -31, -62,   0, -98, -74;
/M: SY='E';  M= -69, -88,  56,  71, -94,  -3, -65, -94, -18, -90, -85, -25, -71, -41, -65,   3, -67, -88, -95, -82;
/M: SY='R';  M= -75, -90,  15, -59, -74, -84, -10, -76,  33, -37, -69, -64, -82,  20,  68, -70, -71,  -9, -80,  27;
/M: SY='A';  M=  66, -74, -76, -72, -81,  -6, -77, -73, -73,  -9, -69, -69, -29, -69, -77,  33, -30, -65, -87, -79;
/M: SY='H';  M= -74, -86, -68, -68, -32, -82, 124, -71, -71, -71, -62, -58, -81, -63, -67, -29, -19,  24,-106, -52;
/M: SY='G';  M= -62, -81, -62, -76, -89,  65, -20, -91, -70, -92, -82,  65, -79, -69, -77,  10,  -2, -87, -92, -83;
/M: SY='Q';  M= -69, -92, -67, -48, -91, -78, -58, -77, -53, -71,  54, -62, -77, 115, -53, -61, -72, -80, -82, -69;
/M: SY='D';  M= -78, -91, 109, -32, -98, -74, -63, -96, -65, -95, -94, -45, -77, -64, -73, -66, -67, -93,-113, -81;
/M: SY='L';  M= -77, -79, -94, -86, -51, -96, -78, -42, -88,  81, -38, -94, -61, -81, -85, -87, -73, -50, -81, -64;
/M: SY='G';  M= -59, -87, -74, -86, -93,  93, -81,-101, -80, -96, -85, -60, -78, -77, -87, -59, -78, -94, -84, -88;
/M: SY='T';  M= -25, -80,  -4, -64, -17, -78, -14, -69, -44,   8, -64, -63, -78,  54, -34,   4,  56, -68, -85, -15;
/M: SY='A';  M=  64, -79, -79, -70, -81, -67, -79, -71, -74,   1, -67, -77,  62, -72, -80, -19, -64, -66, -86, -81;
/M: SY='G';  M= -58, -85, -73, -84, -92,  89, -80, -99, -78, -95, -85, -60, -78, -75, -85,   9, -73, -92, -85, -87;
/M: SY='S';  M= -51, -74, -66, -67, -84, -59, -69, -84, -67, -88, -81, -54, -74, -58, -71,  98, -46, -76, -93, -76;
/M: SY='C';  M= -72, 143, -92, -92, -82, -87, -92, -89, -88, -80, -80, -78,-103, -95, -94, -74, -72, -77,-112, -93;
/M: SY='L';  M= -75, -79, -94, -86, -53, -95, -78, -15, -86,  71,  53, -91, -92, -79, -84, -86, -72,  -3, -83, -63;
/M: SY='P';  M= -40, -91, -72, -59, -89, -78, -68, -82,  15, -82,  22, -67,  64,  49,  45,   5, -54, -82, -86, -77;
/M: SY='R';  M= -72, -88, -72, -61, -83, -82, -25, -52,  41, -79,   7, -64, -81, -53,  82,   4, -69, -29, -86, -72;
/M: SY='F';  M= -86, -82, -97, -93, 110, -93, -75, -59, -88, -51, -61, -87, -96, -98, -85, -84, -77, -64, -50,  16;
/M: SY='S';  M= -58, -76, -65, -69, -80, -65,   8, -80, -67, -83, -77,  18, -74, -63, -72,  75,  48, -74,  44, -72;
/M: SY='T';  M= -63, -74, -70, -72, -75, -78, -78, -22, -69, -27, -14, -61,   6, -72, -77,  -6,  93, -60, -95, -75;
/M: SY='M';  M= -22, -79, -91, -82, -60, -85,  10, -33, -77,  15, 122, -80, -82, -69, -75, -79, -70, -53, -85, -61;
/M: SY='P';  M= -75,-100, -76, -65, -95, -77, -79, -84, -73, -94, -81, -81, 115, -75, -85, -16, -67, -88, -90, -92;
/M: SY='F';  M= -79, -82, -92, -89,  89, -91, -70, -31, -83, -52,  41, -83, -91, -87, -82, -79, -11,  -8, -55,  52;
/M: SY='M';  M=  12, -77, -87, -81, -60, -84, -77, -12, -80,  51,  61, -81, -85, -75, -81, -36,  13, -19, -85, -67;
/I:         I=-24; MD=-61;
/M: SY='F';  M= -48,  -7, -85, -82,  70, -88, -68, -64, -77, -30, -64, -14, -93,   5, -20, -34, -37, -14, -59,  64; D=-24;
/I:         I=-24; MD=-61;
/M: SY='C';  M= -74, 141, -93, -94, -84, -89, -93, -91, -89, -81, -82, -80,-104, -97, -96, -76, -74, -78,-114, -95; D=-24;
/I:         I=-24; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='N';  M= -72, -82,  34,  11, -90, -18, -58, -89, -19, -93, -82,  92,  -1, -60, -67, -58, -40, -89,-102, -82;
/M: SY='I';  M= -53, -86, -87, -80, -17, -91, -82,  67, -75,   0,   9, -80,  11,   1,   3, -24, -49,  -5, -83, -67;
/I:         I=-30; MD=-77;
/M: SY='N';  M= -74, -83,  12, -67,   7,  -6,  20, -83, -65, -84,   4,  88,  -2, -23, -72, -61, -33, -85, -95, -72; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='N';  M= -68, -82,  29,   3, -88,   8, -61, -84, -61, -85,  14,  74, -78,  25, -68,  -1,  -4, -83, -97, -79;
/M: SY='V';  M= -20, -77, -81, -77, -70, -86, -85, -14,   7, -58, -58, -13, -83, -76, -18, -68,  15,  73, -95, -73;
/M: SY='C';  M= -22, 141, -90, -90, -82, -85, -90, -88, -86, -79, -79, -77,-100, -93, -92, -72, -71, -75,-109, -92;
/M: SY='N';  M= -74, -85, -22, -18, -80, -70,  74, -85, -60, -85, -73,  82,  -2,  27, -33, -47, -65, -49, -95,   3;
/M: SY='Y';  M= -78, -86, -86, -86,  65, -88, -62,   2, -81, -46, -59, -82, -92, -80, -79, -13, -72,  -9, -49,  92;
/M: SY='A';  M=  78, -72, -73, -70, -83, -61, -75, -74, -71, -29, -70,  14, -77, -68, -76,   7, -60, -64, -87, -80;
/M: SY='S';  M= -59, -79, -68, -11, -81, -68, -66, -77, -60, -75,  54, -60, -75,  23,  19,  75, -25, -74, -89, -73;
/M: SY='R';  M= -77, -92, -71, -62, -86, -85, -62, -92, -36, -86, -75,   8, -85, -52, 102, -70, -36, -86, -88, -74;
/M: SY='N';  M= -73, -80, -48, -64, -85, -64,  45, -87, -18, -91, -77, 105, -82,   5, -63, -56, -60, -89,-102, -43;
/M: SY='D';  M= -75, -91,  99,  18, -97,  -1, -65, -97, -64, -94, -92, -48, -76, -62, -73, -65, -69, -92,-107, -82;
/M: SY='Y';  M= -78, -91,  11, -19, -53, -85, -56, -79,  31, -75, -69, -68, -84, -59,  49, -72, -73, -80, -59,  89;
/M: SY='S';  M= -50, -72, -63, -64, -82, -59, -67, -81, -63, -84, -78, -34, -72, -57, -23,  96,   0, -73, -90, -74;
/M: SY='Y';  M= -81, -88, -84, -85,  43, -89, -53, -32, -78,  -2, -56, -83, -93, -75, -75, -78, -75, -65, -42, 110;
/M: SY='W';  M= -84,-108,-112, -89, -50, -83,-110, -80, -82, -34, -80,-105, -89, -81, -85, -92, -96, -94, 167, -37;
/M: SY='L';  M= -76, -79, -16, -82, -51, -94, -77, -42, -86,  81, -39, -89, -93, -79, -84, -85, -72, -50, -81, -63;
/M: SY='S';  M=  21, -73, -11, -65, -84, -36, -70, -81, -67, -84, -77, -56, -73, -61, -72,  83,  13, -72, -91, -77;
/M: SY='T';  M= -60, -71, -66, -69, -77, -75, -76, -69, -66, -74, -70, -55, -69, -69, -74,  19, 101, -61, -97, -75;
/M: SY='P';  M=  15, -81,  11, -67, -79, -45, -73, -68, -71,   3, -67,  21,  63, -71, -78, -17,  22, -19, -91, -79;
/M: SY='E';  M=  49, -80, -60,  52, -84, -58, -70, -21, -17, -76, -71,  -2, -73,  -4,  -8, -59, -24, -15, -88, -78;
/M: SY='P';  M= -25, -93, -13, -62, -86, -77, -74, -76, -37,  -9, -54, -75,  98,  31, -76, -69, -18, -79, -87, -83;
/M: SY='M';  M= -73, -84, -10, -76, -62, -88,  12,  35, -68,  -2,  92, -75, -31, -68,  26, -77, -70, -13, -82,  -2;
/M: SY='P';  M= -71, -92, -75, -66, -85, -76, -75, -76, -37, -21,   5, -31, 101, -71, -16,   7, -24, -79, -88, -84;
/I:         I=-24; MD=-61;
/M: SY='M';  M= -90,-103, -86,  15, -94, -99, -83, -80, -83, -77,  80,   5,  10,  11, -87, -89, -87, -39,-107, -90; D=-24;
/I:         I=-24; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='M';  M= -78, -87, -98, -89, -70, -92, -73, -55, -84,  -6, 118, -86, -89, -29, -82, -19, -76, -62, -92, -69; D=-24;
/I:         I=-24; DM=-61;
/M: SY='M';  M=  36, -78, -72,   0, -75, -73, -68, -21,  -4, -60,  88, -18, -75,  21, -66, -20,   1, -61, -85, -70;
/M: SY='P';  M= -28, -99, -76, -65, -94, -76, -79, -81, -72, -90, -19, -82, 116, -75, -84, -72, -68, -85, -88, -91;
/M: SY='I';  M= -29, -80, -92, -87, -59, -92, -87,  61, -85,  26,  17, -86, -86, -81, -86, -42, -65,  44, -86, -67;
/M: SY='P';  M= -23, -82, -66,  -7, -81, -48, -68, -79,  13, -80,   3, -32,  40,  37,  -6,  36,  31, -76, -48, -76;
/M: SY='G';  M= -19, -84,  -5,  34, -86,  55, -73, -24, -68, -80, -75,   4, -30,  -1, -75, -17, -68,   0, -88, -81;
/M: SY='R';  M= -35, -84, -12,  33, -84, -47,   3, -53, -23, -82, -74,   9, -74,  35,  44,   9,  24, -78, -89, -37;
/M: SY='E';  M=  25, -83,  30,  42, -81, -43, -64, -45, -61, -30, -72,  22, -75,  40, -66, -16, -65, -75, -86,  -1;
/M: SY='I';  M= -71, -82, -88, -84, -59, -92, -85,  68, -17,  30,  -7, -81, -84, -78, -81, -22,  -5,   6, -84, -66;
/M: SY='E';  M=  -1, -89,   0,  56, -91, -80, -67, -88,  14, -83,   5, -66,  -5,  23,  29, -32, -70, -83, -90, -79;
/M: SY='P';  M= -75, -97,  17,  -3, -95, -28, -74, -89,   7, -93, -82, -29,  89,  21, -71, -59, -71, -90,   6, -85;
/M: SY='Y';  M= -82, -93, -80, -78,  16, -88,  34, -72, -69, -67, -63, -77, -92,   7,   9, -76, -77, -76, -48, 107;
/M: SY='I';  M= -77, -89, -98, -96,  -7,-102, -97,  94, -91, -44, -48, -88, -86, -88, -94, -85, -70, -21, -83, -65;
/M: SY='S';  M= -13, -76, -69, -69, -84, -47, -71, -82, -69, -84,   8, -34, -76, -61, -73,  91, -43, -75, -93, -77;
/M: SY='R';  M= -78, -95, -75, -62, -88, -88, -64, -94,  -5, -87, -76, -67, -86, -51, 103, -72, -77, -88, -87, -74;
/M: SY='C';  M= -70, 142, -90, -90, -80, -86, -90, -82, -86, -76, -77, -77,-101, -94, -92, -73, -70, -25,-110, -90;
/M: SY='T';  M=  21, -73, -75, -74, -74, -72, -80,  -1, -73, -65, -64, -66, -76, -71, -78,  41,  50,  38, -92, -74;
/M: SY='V';  M= -62, -76, -88, -21, -64, -93, -92, -30, -82, -50, -21, -86, -87, -83, -84, -75, -60,  91, -97, -71;
/M: SY='C';  M= -71, 142, -90, -91, -79, -87, -90, -24, -86, -76, -76, -77,-100, -93, -93, -74, -70, -71,-109, -90;
/M: SY='E';  M= -69, -90, -42,  99, -93, -85, -63, -93, -12, -86, -81, -65, -65,   1, -58, -66, -70, -86, -89, -82;
/M: SY='A';  M=  61, -73, -75, -73, -82,  19, -79, -68, -73, -75, -70, -67, -76, -70, -78,  20,   9,  10, -88, -79;
/M: SY='P';  M= -73, -94, -72, -64, -90, -77,  17, -46, -18, -88, -76, -12, 102, -70, -19, -29,   5, -82, -90, -83;
/M: SY='T';  M=  49, -72, -70, -69, -82, -17, -75, -75, -69, -78, -73, -61, -49, -67, -75,  45,  58, -65, -90, -78;
/M: SY='H';  M= -72, -87, -71, -67, -75, -80,  55,  32, -63, -66,  19,  26,  23,  44,   9, -19, -67,  -8,  33, -66;
/M: SY='V';  M=  37, -75, -84, -79, -66, -78, -83,  10, -78, -28, -57, -78, -45, -77, -81, -11, -19,  60, -86,   0;
/M: SY='I';  M= -75, -85, -97, -93,  20, -98, -90,  75, -88,  -9,  35, -88, -87, -86, -90, -84, -70,  20, -81, -62;
/M: SY='A';  M=  83, -75, -81, -74, -86, -64, -82, -76, -76, -34, -72, -76, -80, -73, -81, -55, -41, -64, -89, -83;
/M: SY='V';  M= -72, -83, -99, -94,  19,-100, -96,  11, -91,  -8, -23, -94, -95, -93, -92, -84, -70,  71, -91, -68;
/M: SY='H';  M= -82, -93, -65, -66, -80, -83, 136, -98, -70, -81, -66, -55, -82, -59, -64, -71, -80, -98,-116, -49;
/M: SY='S';  M= -53, -76, -68, -69, -86, -61, -71, -86, -69, -90, -83, -56, -76, -61, -73,  96, -48, -78, -95, -78;
/M: SY='Q';  M= -71, -97, -66, -46,-102, -79, -59, -88, -52, -83, -70, -62, -79, 119, -52, -61, -74, -90, -84, -73;
/M: SY='T';  M= -65, -80,  50, -64, -86, -12, -75, -78, -70, -83, -79, -56, -76, -70, -77,  35,  66, -27,-101, -80;
/M: SY='T';  M= -71, -83, -77,   1, -71, -88, -77,  31, -69,   4,  36, -73, -81,   0,   9, -12,  41, -23, -90, -72;
/M: SY='T';  M= -20, -82,  23,  -9, -83, -74,  31, -69, -66, -34, -74,  12, -77,  26, -71,  34,  37, -77, -96, -33;
/M: SY='I';  M= -76, -87, -15, -89, -61, -99, -92,  78, -89,  14, -48, -86, -88, -86, -91, -84, -70,  17, -88, -69;
/M: SY='P';  M= -77,-102, -78, -66, -97, -80, -80, -85, -73, -94, -81, -82, 111,   6, -84, -73, -17, -89, -91, -93;
/M: SY='P';  M= -46, -92,  22,  18, -93, -78,  25, -85, -35, -88, -79,   1,  63,  36, -71, -19,  -2, -45, -96, -81;
/M: SY='C';  M= -73, 141, -93, -93, -84, -89, -93, -90, -89, -81, -81, -79,-104, -97, -96, -76, -73, -78,-113, -94;
/M: SY='P';  M= -79,-103, -80, -68, -19, -81, -82, -85, -76, -93, -82, -86, 114, -79, -88, -76, -72, -90, -89, -90;
/M: SY='N';  M=  -4, -85, -13, -45, -87,  16,  27, -81, -67, -36, -75,  32,   6,  26, -16,  19, -65, -24, -94, -78;
/M: SY='G';  M= -45, -86, -65, -82, -92,  79, -80, -95, -37, -94, -84, -15, -79, -76, -50, -33,  18, -89, -88, -87;
/M: SY='W';  M= -88,-113,-116, -92, -53, -86,-116, -86, -84, -83, -86,-109, -91, -84, -88, -95,-100,-101, 167, -39;
/M: SY='R';  M= -61, -86,  24,  25, -82, -56, -23,  12, -60, -51, -72, -18, -79, -62,  35,  16,  13, -21, -95, -77;
/M: SY='S';  M= -60, -82, -61,  37, -89,  12, -71, -88, -66, -89, -83,  -4, -22, -60, -73,  66,  -8, -56, -94, -82;
/M: SY='L';  M= -79, -81, -97, -88, -53, -97, -79, -44, -89,  76,  34, -95, -95, -82, -86, -89, -75, -52, -83, -65;
/M: SY='W';  M= -88,-113,-115, -92, -52, -86,-113, -85, -84, -83, -86,-108, -92, -84, -88, -94,-100,-100, 166, -16;
/M: SY='I';  M= -70, -83, -79, -42, -72, -87, -84,  63,  16, -61, -61, -70, -78, -42, -74,  -5,  53, -48, -90, -74;
/M: SY='G';  M= -61, -89, -77, -88, -95,  91, -83,-103, -82, -98, -87, -62, -80, -79, -89, -61, -80, -96, -86, -90;
/M: SY='Y';  M= -82, -89, -88, -88,  55, -92, -59, -54, -82, -60, -61, -86, -96, -80, -79, -80, -76,   3, -46, 103;
/M: SY='S';  M= -53, -76, -68, -69, -86, -61, -71, -86, -69, -90, -83, -56, -76, -61, -73,  96, -48, -78, -95, -78;
/M: SY='F';  M= -86, -84, -98, -94, 101, -95, -76, -59, -90,  -3, -60, -89, -98, -96, -87, -86, -79, -65, -54,  30;
/M: SY='L';  M= -47, -82, -95, -89, -25, -96, -82,  30, -87,  49,  38, -90, -91, -83, -86, -84, -41,  17, -82,  -2;
/M: SY='M';  M= -74, -82, -94, -83, -63, -88, -67, -48, -78,   1, 127, -82, -84,  -6, -76, -82, -72, -55, -86, -63;
/M: SY='H';  M= -83, -95, -72, -71,   2, -87, 117, -92, -74, -80, -70, -63, -87,   8, -70, -41, -20, -92, -94,  21;
/M: SY='T';  M= -68, -77, -72, -76, -83, -83, -83, -75, -73, -79, -76, -26, -75, -77, -81, -51,  98, -67,-104, -81;
/M: SY='S';  M=  35, -82, -78, -79, -90,  32, -81, -86, -78, -56, -21, -68, -82, -73, -83,  47, -13, -78, -94, -85;
/I:         I=-28; MD=-71;
/M: SY='A';  M=  60, -84,   9, -77, -92, -27, -88, -74, -82, -82, -79, -78, -45, -80, -87, -33, -71,  13, -99, -89; D=-28;
/I:         I=-28; MI=-71; MD=-71; IM=-71; DM=-71;
/M: SY='G';  M= -70, -95, -78, -89,-101,  77, -84,-107, -84,-104, -92,  16, -88,  -9, -91, -67, -84,-102, -94, -95; D=-28;
/I:         I=-28; DM=-71;
/M: SY='A';  M=  38, -86,  20, -73, -94,   2,  36, -89, -78, -90, -83, -10, -85, -74, -69,  13, -18, -48,-102, -83;
/M: SY='E';  M= -74, -97, -41,  63,-100,  27,  21,-102, -67, -95, -88, -70, -79,  26, -74, -15, -79, -96, -97, -86;
/M: SY='G';  M= -54, -94, -82, -94,-101,  85, -89,-108, -88,-104, -93, -68, -86, -85, -95, -67, -86,-102, -92, -96;
/M: SY='G';  M= -27, -88, -81, -86, -13,  54, -86, -49, -83, -89, -84, -69, -85, -81, -89,  23,  27, -48, -93, -84;
/M: SY='G';  M= -67, -95, -82, -94,-101,  85, -89,-109, -88,-104, -93, -68, -86, -85, -95, -54, -86,-102, -92, -96;
/M: SY='Q';  M= -77,-102, -73, -52,-106, -85, -65, -92, -58, -87, -13, -68, -85, 112, -58, -67, -80, -94, -90, -78;
/M: SY='S';  M=  33, -85, -32, -74, -92, -16, -78, -87, -76, -46, -31,  12, -34,   6, -80,  46, -65, -80, -98, -86;
/M: SY='L';  M= -85, -87,-102, -94, -59,-104, -86, -50, -96,  73, -46,-102, -61, -89, -93, -95, -81, -58, -89, -71;
/M: SY='S';  M=  20, -85, -79,  -3, -87, -21, -82, -66, -77, -78,  24, -74, -84,  -4, -81,  36, -11,  11, -98, -84;
/M: SY='S';  M= -46, -83, -74, -76, -93,  -7, -78, -93, -76, -96, -89, -63, -82, -68, -80,  86, -56, -85, -99, -85;
/M: SY='P';  M= -80,-105, -84, -74,-101, -84, -87, -89, -80, -99, -87, -87, 103, -82, -92,  -5, -33, -58, -98, -98;
/M: SY='G';  M= -67, -95, -82, -94,-101,  85, -89,-109, -88,-104, -93, -68, -86, -85, -95, -67, -86,-102, -92, -96;
/M: SY='S';  M= -59, -82, -74, -75, -92, -67, -77, -92, -75, -95, -89, -62, -82, -66, -79,  91, -53, -84,-100, -84;
/M: SY='C';  M= -79, 136, -99, -99, -89, -95, -99, -96, -95, -87, -87, -85,-110,-103,-101, -82, -79, -84,-119,-100;
/M: SY='L';  M= -85, -87,-102, -94, -59,-103, -85, -50, -95,  71,  23,-101,-101, -88, -92, -95, -81, -58, -89, -71;
/M: SY='E';  M= -81,-102, -53,  87,-105, -96, -74,-105, -62, -97, -92, -77, -77,  13, -71, -77, -82, -98,-100, -93;
/M: SY='D';  M= -86,-102,  67,  47,-104, -89,  42,-106, -53,-100, -94, -32, -84, -25, -77, -77, -80,-102,-113, -86;
/M: SY='F';  M= -97, -92,-109,-104, 101,-104, -88, -70,-100, -61, -72, -98,-107,-110, -97, -95, -88, -75, -61, -24;
/M: SY='R';  M= -88,-104, -84, -72, -97, -98, -73,-104, -44, -96, -85, -77, -96, -61,  96, -82, -87, -97, -97, -83;
/M: SY='A';  M=  57, -85, -85, -81, -87, -73, -84, -85, -45, -88, -83, -78, -88, -77, -84,  32, -51, -45, -92,   7;
/M: SY='T';  M=   7, -87, -79, -78, -91, -82, -36, -20, -77, -84, -80,   2, -85,  23, -82,  14,  51, -35,-103, -86;
/M: SY='P';  M= -87,-113, -88, -76,-107, -89, -91, -95, -84,-105, -91, -94, 107, -87, -96, -84, -80,-100,-100,-104;
/M: SY='F';  M= -90, -91,-107,-103,  90,-104, -90, -62, -98, -61, -70, -98,-105,-107, -96, -93, -84,  18, -67, -13;
/M: SY='I';  M= -86, -97,-107,-104, -69,-111,-105,  80,-100,  -6, -55, -98, -96, -96,-102, -95, -80, -19, -95, -77;
/M: SY='E';  M= -80,-102, -53,  89,-104, -34, -75,-106, -63, -98, -94, -77, -77, -56, -73, -77, -82, -98,-101, -95;
/M: SY='C';  M= -82, 133,-102,-102, -92, -98,-102, -99, -98, -90, -90, -88,-113,-106,-104, -85, -82, -87,-122,-103;
/M: SY='H';  M= -84, -96, -67, -74, -95, -30,  93,-102, -73, -96, -82,  61, -91,  18, -74, -30, -78,-102,-115, -73;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='G';  M=  -3, -95, -81, -47,-102,  65, -87,-105, -81,-103, -93,   1, -29, -82, -12, -70, -84, -98, -97, -96;
/M: SY='R';  M= -85,-101, -48, -70, -96, -55,  26, -93,  18, -92, -82, -74, -93,  17,  69, -80, -83, -21, -99, -81;
/M: SY='G';  M= -70, -98, -85, -97,-104,  82, -92,-112, -90,-107, -96, -71, -89, -88, -71, -70, -89,-105, -95, -99;
/M: SY='T';  M= -77, -88, -79, -78, -89, -90,  36, -83, -48, -83,  18, -35, -84,  -8,  -5, -41,  73, -78,-107, -80;
/M: SY='C';  M= -82, 133,-102,-102, -92, -98,-102, -99, -98, -90, -90, -88,-113,-106,-104, -85, -82, -87,-122,-103;
/M: SY='H';  M= -84, -95, -67, -76, -91, -80,  97,-101, -75, -96, -82,  66, -92, -70, -76,  -9, -76,-102,   7, -70;
/M: SY='Y';  M= -93,-101, -93, -95,  36, -99,   6, -77, -88, -72, -71, -92,-104, -85, -85, -88, -87, -82, -52, 102;
/M: SY='Y';  M= -93,-101, -21, -93,  45, -99, -67, -78, -89, -73, -74, -92,-104, -88, -87, -89, -88, -83,  51,  94;
/M: SY='A';  M=  40, -89,  10,  14, -99, -25, -83, -94, -78, -95, -89, -73, -34, -73, -84,  29, -51, -84,-101, -92;
/M: SY='N';  M= -32, -89,   8, -76, -95, -43, -75, -88, -75, -95, -87,  69, -10, -76, -83, -24,  31, -32,-112, -91;
/M: SY='S';  M= -10, -91, -78, -13, -91, -83, -80, -21,  17, -39,  -8, -20, -86,  21, -72,  31, -13, -46, -99, -85;
/M: SY='Y';  M= -34, -95, -87, -87,  -8, -34,   8, -80, -14, -36, -74, -82, -95, -81, -81, -77,  24, -80, -67,  81;
/M: SY='S';  M= -63, -85, -78, -80, -93, -34, -82, -87, -79, -94, -89, -67, -86, -72, -84,  81, -37, -19,-104, -87;
/M: SY='F';  M= -96, -94,-106,-103,  94,-103, -82, -71, -97, -63, -71, -97,-107,-105, -94, -94, -88, -76, -59,  40;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='W';  M= -96,-120,-121,-101, -59, -95,-114, -93, -92, -90, -92,-115,-100, -92, -95,-102,-107,-106, 154,  14;
/M: SY='L';  M= -87, -90,-105, -97, -62,-106, -87, -53, -97,  66,  40,-103,-103, -90, -94, -97, -84, -61, -92, -74;
/M: SY='T';  M=  31, -85, -86, -83, -87, -84, -89, -25, -79, -80, -77, -78, -87, -81,  -8, -14,  49,   2,-100, -38;
/M: SY='T';  M= -19, -85, -83, -84, -86, -85, -89,  -1, -82, -78, -77, -40, -86, -81, -88,  34,  53,   9,-105, -85;
/M: SY='I';  M= -83, -92, -39, -97, -68,-107, -97,  41, -97,  35, -56, -98,-100, -94, -98, -93, -79,  27, -97, -78;
/M: SY='E';  M= -83, -99,  46,  50,-102, -49, -73,-100, -51, -98, -15,  30, -17, -66, -29, -75, -48, -97,-108, -92;
/M: SY='P';  M= -27,-100,  31,  33,-101, -59, -18, -91, -46, -95, -60, -50,  45, -20, -40, -35, -78, -22,-105, -92;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='H';  M= -80, -95, -20,  -8, -89, -39,  54, -16, -66, -13, -76,   8, -89,  29, -42,  13, -32, -83,-103, -79;
/M: SY='Q';  M= -57, -97,  21,   2, -67, -85, -72, -97, -18, -96, -87,  26, -87,  59,   3, -29,  -8, -95,-102, -86;
/M: SY='Q';  M= -83, -99, -34, -26,  20, -93, -75, -77, -74, -71,  71, -80,  -1,  73, -75, -80, -82, -66, -89, -71;
/M: SY='F';  M= -76, -93,-102, -97,  90, -77, -88, -73, -92, -67, -75, -92,-102, -24, -55,  -8, -84, -55,  33, -46;
/I:         I=-30; MD=-77;
/M: SY='Q';  M= -54, -99, -75,  17,-103, -49, -78, -98, -28, -97, -88,  -6, -90,  47,  21,  10, -21, -53,-103, -90; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='K';  M= -28, -97, -19, -45, -94, -53, -81, -28,  40, -72,  17, -76, -90,  11,  15, -16, -62, -23, -98, -85;
/M: SY='P';  M= -88,-112, -88, -78,-107, -90, -92, -95, -85,-105, -92, -93, 103, -88, -97, -84, -21, -99,-102,-104;
/M: SY='E';  M= -62, -97, -77,  25, -91, -93, -10, -10, -18, -70,   5, -34, -89,  19,  10,  -7, -25,  -4,-101, -85;
/M: SY='Q';  M= -43,-101, -83, -72, -41,  -6, -52, -97, -45, -98, -87, -77,  51,  57, -20,  14, -78, -96, -97, -89;
/M: SY='Q';  M= -69,-101,   7,  20,  -5, -32, -76, -96, -70, -61, -85, -73, -28,  67, -42,   0, -80, -95, -96, -82;
/M: SY='T';  M= -74, -84, -82, -85, -87, -92, -92, -40, -81, -81, -79, -72, -83, -86, -89, -61,  87,  -4,-110, -87;
/M: SY='L';  M= -53, -92,-105, -98, -64,-105, -89,  -2, -97,  52,  22,-101,-102, -91, -96, -94, -55, -15, -91,  -5;
/M: SY='K';  M= -84, -99, -77, -34,-101, -92, -81,-100,  82,-100, -88, -71, -12, -63, -49, -78, -35, -96, -95, -89;
/M: SY='A';  M=  56, -87, -82,  -1, -97, -54, -87, -87, -42, -90, -84, -80, -87, -29, -39,   2, -57, -30, -99, -92;
/M: SY='G';  M= -20, -96,  15, -38,-103,  57, -87,-105, -46,-104, -96, -29, -89, -81, -90,   2, -81, -81,-101, -96;
/M: SY='Q';  M= -84,-100,   2,  31, -41, -40, -45, -97, -70, -44, -87,  32, -36,  47, -33, -32, -80, -97,-103, -88;
/I:         I=-21; MD=-53;
/M: SY='L';  M= -26, -94,-100, -95, -44, -22, -93,  -2, -93,  41, -63, -94,-100, -27, -54, -86,   5, -67, -97, -82; D=-21;
/I:         I=-21; MI=0; MD=-53; IM=0; DM=-53;
/M: SY='R';  M= -95,-108, -88,  13, -93,-108, -22, -90, -14,  12, -80, -91,-101, -15,  41, -93, -93, -92,-105, -90; D=-21;
/I:         I=-21; DM=-53;
/M: SY='S';  M= -46, -93,  -5, -29,-101, -83, -81, -97,   7, -99, -92,   9, -88,  -1, -61,  41,  19, -91,-107, -91; D=-21;
/I:         I=-21; DM=-53;
/M: SY='R';  M= -89,-104, -85, -79, -96, -97,  19,  -8,  15, -92, -84,   2, -97, -70,  61, -41, -85, -56,-104, -86; D=-21;
/I:         I=-21; DM=-53;
/M: SY='V';  M= -82, -95,-108,-103, -76,-111,-108,  46,-100, -23, -63,-101,-101,-100,-103, -93, -35,  51,-105, -84;
/M: SY='S';  M= -66, -89, -81, -82, -99, -75, -84, -72, -82,-101, -95, -69, -89, -74, -86,  83, -61, -90,-107, -91;
/M: SY='R';  M= -92,-108, -88, -75,-101,-101, -78,-107,  -5,-100, -89, -81, -99, -65,  88, -86, -90,-101,-100, -88;
/M: SY='C';  M= -87, 127,-107,-107, -98,-103,-107,-104,-103, -95, -95, -93,-118,-111,-110, -90, -87, -92,-127,-108;
/M: SY='Q';  M= -24,-104, -85, -69,-106, -94, -80, -47, -67, -94, -85, -79, -94,  80,  20, -38,  -7, -68,-101, -89;
/M: SY='V';  M= -79, -93,-110,-104, -80,-111,-112, -23,-101, -66, -69,-105,-105,-104,-103, -93, -77,  75,-114, -88;
/M: SY='C';  M= -66, 126,-107,-107, -98,-103,-107,-105,-103, -95, -95, -94,-118,-111,-110, -90, -88, -92,-127,-108;
/M: SY='M';  M= -89,-100,-100, -27, -83,-105, -86,   4, -84, -29,  87, -95, -98, -20,   6, -94, -56, -30,-102, -82;
/M: SY='K';  M= -92,-107, -87, -74,-100,-100, -85,-104,  61,-100, -15, -80, -95, -69,  42, -87, -88,-101,  32, -87;
/M: SY='H';  M= -75,-102, -84, -86, -93, -95,  37,  -8, -20, -90, -62,  33,-100, -30,  21, -25, -64, -14,-108, -24;
/M: SY='P';  M= -50,-107, -37, -91,-106, -16, -96, -99, -53, -40, -95, -16,  12, -15, -13,  -4,  -8, -47,-114,-102;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 20 in 20 different sequences
Number of true positive hits 20 in 20 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] Collagen IV NC1
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
20 sequences

CO4A1_BOVIN (Q7SIB2), CO4A1_CAEEL (P17139), CO4A1_DROME (P08120), 
CO4A1_HUMAN (P02462), CO4A1_MOUSE (P02463), CO4A2_ASCSU (P27393), 
CO4A2_BOVIN (Q7SIB3), CO4A2_CAEEL (P17140), CO4A2_HUMAN (P08572), 
CO4A2_MOUSE (P08122), CO4A3_BOVIN (Q28084), CO4A3_HUMAN (Q01955), 
CO4A3_MOUSE (Q9QZS0), CO4A4_BOVIN (Q29442), CO4A4_HUMAN (P53420), 
CO4A4_MOUSE (Q9QZR9), CO4A4_RABIT (P55787), CO4A5_CANLF (Q28247), 
CO4A5_HUMAN (P29400), CO4A6_HUMAN (Q14031)
» more

PDB
[Detailed view]
14 PDB

1LI1; 1M3D; 1T60; 1T61; 5NAX; 5NAY; 5NAZ; 5NB0; 5NB1; 5NB2; 6MPX; 6WKU; 8TXN; 8TYS
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