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PROSITE entry PS51371


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51371
Entry name [info] CBS
Accession [info] PS51371
Entry type [info] MATRIX
Date [info] 01-MAR-2008 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51371
Associated ProRule [info] PRU00703

Name and characterization of the entry

Description [info] CBS domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=57;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=57;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.3582128; R2=0.0073481; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=1115; N_SCORE=8.55; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=714; N_SCORE=5.6; MODE=1; TEXT='RR';
/DEFAULT: M0=-18; D=-80; I=-80; B1=-200; E1=-200; MI=-205; MD=-205; IM=-205; DM=-205;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 842 in 386 different sequences
Number of true positive hits 842 in 386 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 8
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.06 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 4
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] CBS
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
386 sequences

AAKG1_BOVIN (P58108), AAKG1_HUMAN (P54619), AAKG1_MOUSE (O54950), 
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UniProtKB/Swiss-Prot
False negative sequences
8 sequences

CBS_APIME   (Q2V0C9), CNNM2_CAEEL (Q9GYL2), DARB_BACSU  (O31698), 
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PDB
[Detailed view]
226 PDB

1AK5; 1B3O; 1JCN; 1JR1; 1ME7; 1ME8; 1ME9; 1MEH; 1MEI; 1MEW; 1NF7; 1NFB;
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