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PROSITE entry PS51194


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51194
Entry name [info] HELICASE_CTER
Accession [info] PS51194
Entry type [info] MATRIX
Date [info] 01-APR-2006 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51192
Associated ProRule [info] PRU00542

Name and characterization of the entry

Description [info] Superfamilies 1 and 2 helicase C-terminal domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=151;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=146;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.8787699; R2=0.0049794; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=19233.5097656; R2=7.0479798; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1531; H_SCORE=30024; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1129; H_SCORE=27191; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-15; D=-100; I=-100; B1=-400; E1=-400; MI=-255; MD=-255; IM=-255; DM=-255;
...
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Post-processing [info]

PROMOTED_BY PS51192; PS51193
COMPETES_HIT_WITH PS51192(30); PS51196

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 2'750 in 2'732 different sequences
Number of true positive hits 2'750 in 2'732 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 22
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.21 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] Helicase C-terminal
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
2732 sequences

009L_FRG3G  (Q6GZW6), 172L_IIV6   (O55764), A18_ECTVM   (Q8JL96), 
» more

UniProtKB/Swiss-Prot
False negative sequences
22 sequences

CAS3_THET8  (Q53VY2), DHX32_HUMAN (Q7L7V1), DHX32_MOUSE (Q8BZS9), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

RH1_CATRO   (P85441)

		
PDB
[Detailed view]
884 PDB

1A1V; 1C4O; 1CU1; 1D2M; 1D9X; 1D9Z; 1FUK; 1FUU; 1GM5; 1HEI; 1HV8; 1JR6;
» more