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PROSITE entry PS51186


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51186
Entry name [info] GNAT
Accession [info] PS51186
Entry type [info] MATRIX
Date [info] 01-MAR-2006 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51186
Associated ProRule [info] PRU00532

Name and characterization of the entry

Description [info] Gcn5-related N-acetyltransferase (GNAT) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=140;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=135;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.7210873; R2=0.0068247; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=23249.4824219; R2=4.3146853; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1258; H_SCORE=28677; N_SCORE=9.3; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=847; H_SCORE=26904; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-17; D=-50; I=-50; B1=-300; E1=-300; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Post-processing [info]

COMPETES_HIT_WITH PS51187; PS51191; PS51729; PS51730; PS51731

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 739 in 667 different sequences
Number of true positive hits 738 in 666 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 77
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.86 %
Recall (true positives / (true positives + false negatives)) 90.55 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 3
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] PS_Langendijk_Genevaux
Feature key [info] DOMAIN
Feature description [info] N-acetyltransferase
Version [info] 8

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
666 sequences

AAAT_ECOLI  (P46854), AAC2_MYCBO  (P0A5N1), AAC2_MYCFO  (Q49157), 
» more

UniProtKB/Swiss-Prot
False negative sequences
77 sequences

BUT82_GIBZE (I1RV22), GNAT5_ARATH (Q9LR91), HAT11_DICDI (Q86J12), 
» more

UniProtKB/Swiss-Prot
False positive sequences
1 sequence

Y9628_DICDI (Q55DK2)

		
PDB
[Detailed view]
334 PDB

1B6B; 1BOB; 1CJW; 1CM0; 1GHE; 1I12; 1I1D; 1I21; 1IB1; 1J4J; 1KUV; 1KUX;
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