PROSITE entry PS51184

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51184
Entry name [info]	JMJC
Accession [info]	PS51184
Entry type [info]	MATRIX
Date [info]	01-FEB-2006 CREATED; 10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51183
Associated ProRule [info]	PRU00538

Name and characterization of the entry

Description [info]

JmjC domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=161;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=156;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8866572; R2=0.0079286; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=26042.3710938; R2=5.3107991; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1150; H_SCORE=32150; N_SCORE=11.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=582; H_SCORE=29133; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-23; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='P';  M=   0,   9,  17,  14,   0, -46,   5, -29,   1, -22, -13,   4,  49,   2,  -7,  12, -54,  -5,  27, -11;
/M: SY='Y';  M=  -3, -43,   8,   1,   8, -35,  -7, -87, -24, -32, -84,  13,  29,   6,  13,  26,  15, -29,   7,  51;
/M: SY='W';  M=  11, -86,  -6,  -5, -32, -16,  -5, -12,  -7,  -2, -20,  31, -12,  19, -38,  28,   1,   6,  35, -11;
/M: SY='R';  M= -10, -96, -21,  11, -44, -15, -30, -53,  10, -17, -12,   7,  37,  14,  40,   7,   7, -14,  35, -10;
/M: SY='Q';  M= -66, -20,  25,  27, -16, -62,  23, -57,  -6,  24, -18,   6,  20,  28, -14,  13, -27, -13, -97,   9;
/M: SY='Q';  M= -33, -45,  -9, -13,  -6,  -8, -23,   9, -28,  34,  20, -31,  21,  36, -31,   0,   0, -40,  -6,  15;
/M: SY='W';  M= -37, -50,  31,   5, -15, -14,  -7, -63, -12, -18,  -7,  51,-109,  11,  19, -11, -20, -72,  96,  24;
/M: SY='N';  M= -22, -55,  10,  18, -35, -24, -21,   7, -22,   8,  11,  61,  12,   2, -35,  -1, -14, -49, -98,  15;
/M: SY='L';  M=  -6, -15,  32, -10,  30, -43,  -3,   4, -63,  36,   5, -57,-110,  -9, -28, -19, -11,   4,   0,  21;
/M: SY='Y';  M=  27, -10,  16,  -7,  13, -56,   8, -41, -17, -14, -79,  36, -47, -74,  12,  -4,   5, -12, -28,  47;
/M: SY='N';  M= -31, -96,   6,   3,  29, -70,  -4, -28,  33, -19, -76,  43, -39,  15,  34, -14,   5, -22,   4,  -6;
/M: SY='L';  M= -38, -85, -61, -17,   8, -83,  10,  37, -28,  49, -28, -35, -30, -10, -12, -30,  -1,  28,-100, -78;
/M: SY='P';  M= -16, -57, -15, -17, -78, -47, -97,-112, -46, -85, -99, -55, 120, -56, -98, -38, -45, -80,  13,-117;
/I:         I=-11; MD=-27;
/M: SY='E';  M=  -6,-103, -38,  24, -66, -80, -35, -20,  -3, -22, -44,   5,  -5, -18,   4,  12, -10, -20, -21, -32; D=-11;
/I:         I=-11; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='F';  M= -12,  -5, -35, -53,  47,   6, -26, -50, -52,  -8,  -5,   3, -67, -34, -42, -49, -12, -36, -92,   9; D=-11;
/I:         I=-11; DM=-27;
/M: SY='R';  M=   3,-101, -23, -11, -14, -21, -17, -35,  -3, -27, -49, -38, -13,  -7,  30,  18, -10, -34,-106,  -5; D=-11;
/I:         I=-11; DM=-27;
/M: SY='D';  M= -37,-105,  39, -14,  -8,  30,  12, -66, -25,   6, -42,  -7,  18,   1, -57,   5,  -9, -94, -33, -36; D=-11;
/I:         I=-11; DM=-27;
/M: SY='W';  M= -34, -47,  61,   5, -97, -12,  -9, -42,  -9, -34, -91,  51, -15,  -4,   0,  30, -42, -52,  62, -21;
/M: SY='W';  M= -32,  15, -37,-106,   6,-117,  -7,  31, -94,  52,  29, -66, -70, -58,  12, -43, -26,  -2,  77,   3;
/M: SY='L';  M=  -7, -22, -43, -18,  43,-110, -91,  -7, -23,  49,  20, -14, -69, -23,  16, -40, -79,  23,   4, -42;
/M: SY='R';  M=  -8,   6,  41,  22, -57, -33, -72, -68,  -6,-107, -93,  35,  -1,  31,  43,  32,  -4, -61,-110, -63;
/M: SY='D';  M= -32,  -8,  66,  27,   4, -31,  49, -86,  -6, -34, -88,   3,-106,  21, -22, -25, -79,  -5, -88,  43;
/M: SY='L';  M= -57,  20, -66,-108,  30, -57, -49,  40,-106,  52,  15, -14, -61, -44,-106, -24,   2,  20, -89,  -2;
/I:         I=-7; MD=-17;
/M: SY='P';  M= -64,   3,  31,  -6, -47,  38,  23, -58, -11, -51, -55,  11,  46,  -3, -66,   1,  -7, -63,  30, -97; D=-7;
/I:         I=-7; MD=-17;
/M: SY='W';  M=  -3, -98,  11,  14,   3,  -1, -42, -16, -60, -21, -49,  11,  34, -51,  -5,   6,  -5, -31,  60, -25; D=-7;
/I:         I=-7; MD=-17;
/M: SY='S';  M= -12, -44,  16,   8, -37, -37,   4, -41,   0, -17, -24,  -3,  11,  18, -20,  30, -27,  18,-108, -32; D=-7;
/I:         I=-7; MD=-17;
/M: SY='W';  M= -41,  20,  10, -70, -20, -49,  -8,  23,   0,   6,  12, -42,  -5, -18,   8, -37, -10,  17,  29, -28; D=-7;
/I:         I=-7; MD=-17;
/M: SY='Q';  M=  -6, -25, -19,  24,  13,   9,   1, -68, -33, -57, -46,   2,  21,  27,  12,  -3, -21, -37,-104, -26; D=-7;
/I:         I=-7; MD=-17;
/M: SY='G';  M=  -1, -14,  16, -20, -69,  43,-104, -69, -34, -22, -54, -36,  35, -56, -39,  -1, -57,  -8, -27,-116; D=-7;
/I:         I=-7; MD=-17;
/M: SY='W';  M= -49, -48, -13, -29,  22, -49,   8,  -7, -74, -17,   8, -16,   6, -49, -12, -18, -14,  13,  54, -18; D=-7;
/I:         I=-7; MD=-17;
/M: SY='N';  M= -35,  -7,  -1, -21, -53, -11, -43, -47, -75, -41, -49,  49,  41, -92, -72, -33,  21, -31, -33, -45; D=-7;
/I:         I=-7; MD=-17;
/M: SY='T';  M= -65,  -2,   3,  -1, -21, -13, -51, -35,  -1, -28, -95,  -9, -31, -26, -22, -51,  23, -41,-121, -26; D=-7;
/I:         I=-7; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='P';  M=   6, -94, -94, -60, -73, -56, -90, -54,  -1, -29, -83, -40,  50, -11,  33,  21,  22,  10,-113, -58; D=-7;
/I:         I=-7; DM=-17;
/M: SY='W';  M= -57,  11, -82, -90,  35,-101,  -8, -57, -32, -53,  46,  56, -71,   7,  10,  -3,  -5, -51, 102,  55;
/M: SY='L';  M= -10,  41,-118,-110,  17, -64,-103,  45, -76,  50,  22, -63, -70, -31, -65, -40, -56,  33, -93, -22;
/M: SY='W';  M= -19, -32, -60, -49,  24, -78,   5, -15, -99,   9, -71, -11, -68, -89, -18,   9, -82, -39, 100,  93;
/M: SY='M';  M= -16,  -8,-118, -73,  21, -67, -96,  64,-106,  22,  72, -63,-116, -50,-107, -44, -52,  18, -18,  30;
/M: SY='G';  M=   0, -94, -33, -48,-117,  81, -93, -84, -18,-115,-105,  -5, -64, -46, -90,  49,   5,-101, -26,-113;
/M: SY='M';  M= -11, -41, -23, -31, -25, -20, -42, -51, -32, -28,  67, -17,  65,  15, -43,  18,  18,   0,  21, -18;
/M: SY='P';  M=  15,  15, -19,  20, -98,   5, -46, -48,   0, -26, -18, -13,  60, -41, -17,   8,  11, -27,  41, -34;
/I:         I=-17; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='G';  M= -36, -52,  24, -50,  35,  61, -25, -59,   5, -35, -90,  17, -28, -14,  15,   7, -44, -99,-100, -48;
/M: SY='S';  M=  18,  26, -78, -45, -96,  14,   4, -90, -64, -32, -84, -19, -42,  17, -86,  70,  44, -52,-103, -21;
/M: SY='W';  M= -40,   4, -88, -63, -52,  43,  15, -12, -46, -47, -40,  -6,-108,  -4,   3,  16,  43,   8,  62,  30;
/M: SY='T';  M= -32, -37, -90, -58,  53, -98, -30, -18, -41, -17, -39, -75,-102,   5, -42,  34,  80,  -1, -87, -39;
/M: SY='P';  M=   9,  35,  10, -42, -64,  29, -48, -68, -13, -67, -93,   6,  69, -48, -22,  24,  -5, -42,  45, -99;
/M: SY='W';  M=  -1,  19,-114,-111,  41, -46, -99, -16, -50,  35,  29, -66,  38, -93, -67, -62, -11, -56, 113,  -9;
/M: SY='H';  M= -90, -41, -84, -73, -88, -69, 147,-118, -59, -92, -99, -57, -55,  -5, -44, -12, -35,-111,-102, -17;
/M: SY='Y';  M= -34,  39,-106, -98,  30,-115,  12,  18,   3,  -3,  -2, -39,-116, -31,  23, -48, -11,  14,  42,  71;
/M: SY='D';  M= -78,-128, 110,  56,-126, -60, -82,-130, -79,-133,-125, -17,-102, -64, -94, -36, -82,-118,-132, -55;
/M: SY='D';  M=  -6, -92,  57, -14,  26, -61,  24, -47, -61, -72,  25,   0,  43, -16, -59,  15,   3,  16, -21, -44;
/M: SY='H';  M=   1,  28, -57, -23,  18, -24,  68, -32, -86, -16,  25,  32, -15,   9, -34,  12, -56, -38, -21,  57;
/I:         I=-19; MD=-47;
/M: SY='D';  M= -15, -45,  65,  11, -38,  34,  38,-118, -87, -70, -43, -20, -65, -79,  -3,   0, -60,-111, -34,   9; D=-19;
/I:         I=-19; MD=-47;
/M: SY='T';  M= -47, -37,-103,-109, -45, -62,-107, -35, -71,  16,  18,  12,-122,-101,-110,  22,  43, -16,-121,-108; D=-19;
/I:         I=-19; MI=0; MD=-47; IM=0; DM=-47;
/M: SY='Y';  M= -31,  15, -71,-119,  23, -20,   9, -34,-118, -10, -88, -26,  -2,-110, -69,   2, -94, -12,  20,  30; D=-19;
/I:         I=-19; DM=-47;
/M: SY='S';  M=  31, -83, -33, -65, -60, -20, -87, -51, -91, -15, -84,  44,-103, -49, -96,  56, -28,   8, -27, -30; D=-19;
/I:         I=-19; DM=-47;
/M: SY='W';  M= -52,  38,  -1, -34,   1,-120, -98,  43, -67,  22,  -9, -44, -78,  -9,-104, -90,  -6,  39,  94,  -3;
/M: SY='N';  M= -73,  -3, -15, -38,  -5, -93,  21, -22, -79, -10, -42,  89, -62,  35, -83, -15, -71,  -1,   6,  53;
/M: SY='Y';  M=  16,  17,-117,-111,  38,-112,   7,  34,-108,  36, -53,-105,-115, -97,-107, -42, -32,  15,  25,  64;
/M: SY='Q';  M= -25,  -7, -86, -47, -24,-107,  49,   6, -82,  28,  35,  33,-108,  61, -84, -47, -25,  32, -91,   4;
/M: SY='H';  M= -50, -88, -67, -99, -21,  28,  70,  37, -99,  12,  13, -91, -77, -28, -38, -88, -40,  52, -96,   0;
/M: SY='Q';  M= -40,  38, -38,  16,   8,   2,   5, -39,   2, -14, -74, -75,-103,  58,   9,  18,  13, -14,  19,   1;
/I:         I=-2; MD=-5;
/M: SY='G';  M= -26, -44, -92, -45,-121,  83,-109,  -6, -34,-108,-102, -49,  -5, -53, -75, -20, -17, -36, -39,-124; D=-2;
/I:         I=-2; MD=-5;
/M: SY='S';  M=  22,  -3,   8,   5, -50,  16,  10, -74,   7,-112,-102, -76, -39,  -7,  18,  29, -25, -73,-115, -43; D=-2;
/I:         I=-2; MD=-5;
/M: SY='P';  M= -73,-125, -30, -31,-139,  19,-110,-128,   8, -90, -48, -55,  33, -13, -45,   6, -11, -81,-142,-138; D=-2;
/I:         I=-2; MI=0; MD=-5; IM=0; DM=-5;
/M: SY='K';  M= -10,  34, -59, -46, -60, -72, -77, -97,  92, -42, -39, -45, -95,  -6,  41, -41, -34, -62, -32, -51;
/M: SY='R';  M= -65, -19, -31,  -6, -27, -57,  28,  19,   7,   1, -36, -78,-106,  28,  60, -24,  24,  -5, -17,   2;
/M: SY='W';  M=-102, -43, -67,-130,  57, -47,-104, -79, -86, -36, -21, -68,-129, -99,-111, -73, -99,   2, 163, -30;
/M: SY='Y';  M= -72,   7,  -7, -52,  28, -84,  13,   6, -30,   7, -14, -54,-115,  -4,  25, -46,  26,  -2, -21,  78;
/M: SY='L';  M= -22,   3, -63, -75,  33,  -7,-103,  27, -59,  51,  25,-102,-114, -57, -74,   6, -75,  32, -93, -72;
/M: SY='F';  M= -37, -84, -47,-110,  66, -26, -16,  44, -73,  -2, -17, -63, -28,-100, -75, -45,  -1,  16,  34,  59;
/M: SY='P';  M=  14, -20, -10, -22,-117, -28, -27, -40,  -3,-107, -95, -24, 102, -10,  -4,   6, -38, -93,-117,-113;
/M: SY='P';  M=  -9,-100, -12, -19, -67, -17, -86,-103, -35, -67, -38, -12, 101, -17,  -7,  18, -17, -59,  18, -16;
/M: SY='E';  M= -16,   0,  30,  49,-110, -18,  20, -67,  15, -84, -91,   5,  24,  17, -18,   7,  33, -30,-115, -63;
/M: SY='D';  M=  -9, -28,  63,  37, -26, -35,  32, -96, -24, -52, -49,  -8, -16,  45, -46,   3,   0, -34, -21,  11;
/M: SY='W';  M=  21, -87, -11,  -4, -13, -41, -52, -23, -14, -25,  -8, -37,  17,  15,  21,  10,  13,  23,  32,   8;
/M: SY='P';  M=  12, -95,  36,  26, -46, -18,  18, -67, -45,  -5, -11,  36,  39,  -2, -29,  14, -19, -46,-104,  -6;
/M: SY='K';  M=   0,  -3, -41,   8,  14, -67,  10, -66,  49, -14, -78,  28,  33,   4,   8, -19, -14, -40,   7,  -1;
/M: SY='F';  M= -23, -40, -30,  -9,  53, -16, -52,   5, -33,  47,  22, -21,  -1, -39, -53, -48, -41,   4, -85, -15;
/M: SY='Y';  M=   4, -95, -24,  41, -26, -31,   4, -30, -25,   1,   1, -39,   1,   1,  12,   1, -37, -28, -14,  67;
/M: SY='Y';  M=  -4,-101,  28,  25, -33, -21, -23,  -9,  32, -24, -43, -15,  25,  -3,  34, -37, -57, -34, -93,  37;
/M: SY='Y';  M= -10, -47, -21,   4,  30,  -4,  24,  -7, -37,  13, -38, -61, -25,  18,   7,  -6,   6,   6, -84,  31;
/M: SY='P';  M=   2,   6,  -5,  -8,  -7, -12,  -8,  12, -48,  16,  30, -18,  42,   4, -68,  -3, -33,   1,  37, -17;
/M: SY='W';  M= -25, -96,   3,  14,  -2,   4,   8, -14,  17, -13,   2, -16, -12,  16,  11,  11, -12, -23,  60,   9;
/M: SY='E';  M= -38,   0,  33,  38, -14, -93, -38, -51,  27, -48, -39,   9,  13,  15,  11,  36,  -3, -43,-104, -12;
/M: SY='H';  M= -29, -22,  -8,  16, -20,   1,  28,   1,   4,  11, -71, -19,  19, -12,   3,  21,   7, -31, -24,   1;
/M: SY='S';  M=  12,   6,  -1, -10,  24,   7, -24, -34, -20, -13, -49,  14,   4,  -2, -12,  38,  13, -41, -96, -14;
/M: SY='P';  M= -37, -42,  -3,  16,   0, -14, -10,  -4, -10, -14,   3,  -5,  56,   7, -64,  21, -12,  -6, -94,  17;
/M: SY='D';  M=  -8, -18,  41,  30, -19,  -7, -15, -26,  -4, -11, -47,   1,  17, -11, -34,  -6,  -4, -11,  10,  24;
/M: SY='D';  M= -40, -98,  33,  -9, -13,  14,   7, -30,  -4, -25,   6,  24,  33,  32, -42,  -8, -13, -12, -14,  25;
/M: SY='H';  M= -21,   5,  20,   6, -12,  12,  30,  -1, -32, -17, -78,  -1,  -1,  28,   2,  14,  -5, -19, -27,  11;
/M: SY='D';  M= -32, -41,  41,  32,  10, -19,   9, -40, -12, -30,  -8,   2,  32,   5, -20,  13,   2, -13, -15, -29;
/M: SY='E';  M= -32,  -5,   9,  30, -34, -10, -30,  21,  11, -26,  13,  13,  21, -18,   7, -20,   6,   3, -34, -54;
/I:         I=-2; MD=-5;
/M: SY='S';  M= -30,  19,  17, -14,   4, -31, -17, -24,  -6, -23, -48,   5,  22,  30,  -7,  33, -19, -15,  18, -36; D=-2;
/I:         I=-2; MD=-5;
/M: SY='P';  M= -39,  -9,  21, -21,   2,  -6, -10, -13, -14,  21, -12, -24,  30, -15, -35, -13,   0, -26,   7, -13; D=-2;
/I:         I=-2; MD=-5;
/M: SY='D';  M= -19,-105,  39, -13, -38, -11,   1, -24, -25, -11, -42,  11,  11,  11, -32, -36, -27, -14,  38,  10; D=-2;
/I:         I=-2; MD=-5;
/M: SY='D';  M= -23, -45,  35,  14,  21, -16, -94, -22, -34, -23, -19, -12,   8,  -8, -26, -34, -24, -28,  27, -29; D=-2;
/I:         I=-2; MD=-5;
/M: SY='W';  M= -31, -37,  -4,  -7,  18, -42,  29, -18, -28,  -7, -17,   7, -19, -27, -15, -13, -30, -20,  34,   9; D=-2;
/I:         I=-2; MD=-5;
/M: SY='H';  M=  -1, -25,  24,  -3,   8, -56,  37, -23,  -8, -13, -23,   3,  -2, -35, -25, -36, -37, -45, -14, -16; D=-2;
/I:         I=-2; MD=-5;
/M: SY='P';  M= -11, -46, -61,   6, -14, -16,  24, -12,  -9, -26, -49, -24,  31,   6, -35, -46, -25,   3,-118, -97; D=-2;
/I:         I=-2; MD=-5;
/M: SY='D';  M= -31,-112,  39,   7, -65, -35, -37, -35, -22, -18, -26,   0,   5,   7,  -9,   1, -36, -48,-119, -26; D=-2;
/I:         I=-2; MD=-5;
/M: SY='F';  M= -34, -39, -13, -40,  15, -27, -19, -42, -30,  14, -44, -16, -11, -36, -25, -99, -37,   3,-104,   4; D=-2;
/I:         I=-2; MD=-5;
/M: SY='Y';  M= -50,-114, -12,   1,  -7, -87,   3,   8, -33, -33, -18, -64,   5, -36, -26, -57, -40, -22,   2,  33; D=-2;
/I:         I=-2; MD=-5;
/M: SY='D';  M= -53,-118,  13, -11, -27, -30,-102,  -4,  -1,  -2,  -9,  -6,   4, -24, -28, -71, -72, -67,-118,  -8; D=-2;
/I:         I=-2; MD=-5;
/M: SY='S';  M=  -1,-104,  -9, -37, -13, -75,  -7, -19, -21, -32,   1,  -6, -25, -61, -64,   9,   1, -49,   5, -12; D=-2;
/I:         I=-2; MD=-5;
/M: SY='P';  M= -24, -48, -35, -17,-111, -14, -12,-112, -19, -39,-105, -28,  58, -38, -51,   6, -40, -59,  17, -12; D=-2;
/I:         I=-2; MD=-5;
/M: SY='P';  M= -56, -46,  12, -17, -28, -28, -13, -13,  -4, -72,-101, -38,  37, -20,  11, -31, -72, -29,-121, -22; D=-2;
/I:         I=-2; MD=-5;
/M: SY='H';  M= -56, -25,  -2, -32,   9, -84,  20, -91, -24,  -7, -22, -67,  19, -24, -67,  -3, -25, -22,-112, -18; D=-2;
/I:         I=-2; MD=-5;
/M: SY='R';  M= -59, -23,  -3, -53, -17, -65,-105, -73, -43, -16,   4,  -7, -26, -20,   9, -29,   0, -57, -35, -30; D=-2;
/I:         I=-2; MD=-5;
/M: SY='R';  M=-115, -42, -18,   1, -38, -88,-105, -33, -25,  -9, -98, -43,  -3, -60,  19, -58, -52,-106,  -4,   4; D=-2;
/I:         I=-2; MI=0; MD=-5; IM=0; DM=-5;
/M: SY='W';  M=  22,  43,-111,-107,  -6,   1,-105,  10, -58, -16, -39,-104,  41,-100, -76, -22, -38,  30,  45,  -7; D=-2;
/I:         I=-2; DM=-5;
/M: SY='Y';  M= -58,   4, -71, -23,  16,-116,  38,  23, -24,   7,  -1, -26,-116,  17,   7, -47,  -8, -46,  70,  78;
/M: SY='E';  M= -21, -15,  21,  47, -39, -98,  21, -12,  26, -59, -24, -25,-100, -18,  34,   2,  23,   1,-105,  -7;
/M: SY='C';  M=   4,  54, -61, -18,  45, -16, -52,  27,-104, -13,  -1, -62,-113, -70,-108, -79,  12,  53,  25, -44;
/M: SY='V';  M= -80, -19,  15,  36, -43,-113, -41,  37, -45, -19,  -8,  -8, -64, -48, -33, -52,  22,  58,  15, -29;
/M: SY='Q';  M= -84,  23, -98, -69, -74,-117, -40,  -8, -75,  59,  21, -90,-107,  92, -81, -89, -59,  12, -95, -92;
/M: SY='H';  M= -40,  -6, -23,  54,  -6, -38,  58,-105,  37, -71, -91,  29,-101,   8,  43, -19, -50, -70, -29,   1;
/M: SY='P';  M=  37, -46, -82,  10,-114, -66, -89, -96,  -8, -49, -88, -91, 101,  15, -56, -11, -33, -38,-114,-114;
/M: SY='G';  M= -72,-118, -21, -64,-129, 103, -21,-141, -44,-130,-119,   8,-114, -57,-101, -74, -93,-129,-124,-126;
/M: SY='D';  M= -89, -41,  96,  73,-127, -95, -75,-122, -71,-123, -51, -35, -99,  37, -85, -52, -34,-110,-128,-115;
/M: SY='M';  M=  16,  11,-112,-105,  40, -58, -96,  11,-102,  19,  58, -99,-109, -93,-104, -54,  40,  38, -82,   9;
/M: SY='L';  M= -67, -34,-130,-118, -23,-129,-113,  35,-113,  66,  42,-121,-120,-102,-112,-103, -78,  57, -99, -86;
/M: SY='Y';  M= -99, -87,-123,-122,  79,-131,   6,  31,-115,  -5,  -8,-110,-130,-104,-112,-103, -91,   9,  -2,  95;
/M: SY='I';  M= -83, -30,-118,-110,   7,-125,-109,  69, -34,  22,  18,-107,-117,-101,-104, -60,  25,  54, -98, -47;
/M: SY='P';  M= -79,-109, -94, -62,  34, -45, -95,-107, -95, -79, -94, -35, 121, -89,-104, -32, -89,-104,   2, -13;
/M: SY='P';  M=  37, -45, -85, -61,-109, -44, -83, -73, -22,-101, -26, -15,  80, -73,  42,  45, -11, -67,-109, -55;
/M: SY='G';  M= -61,-107, -38, -94, -62,  82, -24, -96,  -4,  -9,  33,   5,-112, -28,  10, -45, -39, -99, -17,  10;
/M: SY='W';  M=  10,  42,-109,-107,   0, -48,   4, -87,-108, -46,   1, -94,-112, -58,-101,   3,  35, -47, 143,  33;
/M: SY='W';  M= -26, -91,-118,-117,  50, -66,  -7,  23,-114, -33, -34,-109,  27, -98,-109, -42, -61, -10, 122,  75;
/M: SY='H';  M= -96,-122, -85, -76, -50,-110, 148,-114, -86,-108,-100, -33,-109, -51, -44, -57, -41, -75, -92,  28;
/M: SY='Q';  M=  14,  21, -24,  -3,  -3, -54,  63, -93, -51, -42,   5, -29, -99,  77, -22,  12, -12, -72,  59,  21;
/M: SY='V';  M=   4, -77,-106,-101, -88,  33, -39,  14, -67, -63, -62, -96, -48,-100,-105, -22,   0,  82,-105, -47;
/M: SY='F';  M= -64, -43, -44,  21,  50,-111,  31,  11, -14,  -9, -66, -49,-109,  31,  14,  -7,  -4,  20,  14,  21;
/M: SY='N';  M=  19,  21, -29, -75,-106, -13, -26, -49, -51,-103, -91,  76, -22,   7, -19,  40,  47, -85,-110, -50;
/I:         I=-11; MD=-29;
/M: SY='L';  M= -39,  14, -13,   5, -16, -79,  27,   5, -71,  43,  16, -33,  20,   0, -44, -14,   5,  -3,-100, -17; D=-11;
/I:         I=-11; MD=-29;
/M: SY='G';  M= -51, -21,  32,  35, -69,  63, -23,-105, -27, -88, -28, -44, -57,   6, -60,   1,   4, -32,-119, -62; D=-11;
/I:         I=-11; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='D';  M= -26,-100,  50,  12,  49, -43,  28, -50, -26, -33, -86,  -9,  10, -20, -22,   8, -21, -59,  10,  37; D=-11;
/I:         I=-11; DM=-29;
/M: SY='C';  M= -21,  74, -15, -82, -35,  -1,  12, -92, -87,-102, -94,  50, -21, -81, -91,  63,  37, -34,-108, -46; D=-11;
/I:         I=-11; DM=-29;
/M: SY='I';  M= -42,  31, -35,-108,  10, -47,-105,  54, -71,  42,  52, -17, -65, -97,-107, -58,  -6,  26, -95, -42;
/M: SY='S';  M=  39, -15, -74, -56, -53, -12,  47, -82,  -2, -31, -43,  41, -58, -14, -77,  53,  17, -10,-108, -87;
/M: SY='V';  M= -41, -85, -86,  40,  34,-121, -46,  47, -96,  19, -30, -63, -28, -45, -62, -90, -36,  49, -89,  12;
/M: SY='S';  M=  38, -34, -71, -41, -33,  11, -79, -54, -58, -71, -88,  51, -60, -76, -55,  58,  45, -46,-104, -30;
/M: SY='W';  M= -22,  26,-101, -23,   9,   4,  11,  29, -52,   3, -60, -58, -75,  12, -51, -63, -13,  46,  84, -15;
/M: SY='N';  M= -73, -96,  10, -29,  11,  16,  36,-102, -37, -56, -94,  99, -45, -71, -30, -24, -15, -45,  26, -14;
/M: SY='F';  M= -75, -44,-112, -77,  91,-121, -80,   3,-106,  -2, -37, -26,-125, -62, -31, -32, -19,  -3,  80,  58;
/M: SY='W';  M=  34,  21, -66, -66, -31, -11,   4,  -6, -48,  13,  13,  -9, -44, -53,  18, -12,   1,   2,  87, -33;
/M: SY='T';  M= -17, -18, -20, -41, -21, -93,  21, -44, -76, -43, -13,  28,  49,   8,  12,  33,  50, -49,   9,  21;
/M: SY='P';  M=  -7, -96,  17, -12, -39, -23, -45, -39,   1,   0, -19, -51,  69,  -3,   6,  19, -19, -22,  36,  -6;
/M: SY='W';  M= -23,  -8,  19,  21, -38, -46,   8, -65, -26, -21,  -5,  31,   5,  22,  -1,  26,  35, -68,  42,   5;
/M: SY='W';  M=  -4, -45,   5, -19,  11,   4,  24, -39, -42, -66, -86,  52, -30,   8, -63,  16, -13, -43, 112, -10;
/M: SY='L';  M=  -1,  -1,  -1, -26,   7, -48, -16,  25, -44,  43, -14, -11, -26,   7, -44, -36, -14,  19, -30, -10;
/M: SY='D';  M=   5, -97,  55,  20, -22, -29, -20, -92, -11, -13, -46,  -4,  27,  19,  -3,  20,  -2, -52, -36,   1;
/M: SY='M';  M= -38, -41, -10,  11,  -2, -70,  27,   0, -60,  22,  48,  24,   4, -33, -16, -35,  14, -11,  19,  38;
/M: SY='S';  M=  13,  14, -13, -37,  -1,  20,  -9, -34, -27,   1,  26, -19,  -4,   4, -30,  30,  -7,  -1,  22, -11;
/M: SY='W';  M=   4, -45,   6, -14,   0, -60, -35, -10,  16,  28,  17, -29, -70,   2,  -1, -22,  -4, -20,  51,  42;
/M: SY='W';  M=   5, -43,   9,  11,  -4, -58,  27, -19,  31, -39, -12,  -4, -22,  30,  13,  23, -20, -43,  45,  -5;
/M: SY='A';  M=  26, -25,   6,  -5,  14, -72,  -3,  -7, -33,  25, -20,  -3,  -6, -78, -20,  23,  -3,   0, -29, -12;
/M: SY='C';  M=  10,  28,  -9, -26,  11, -15, -45,  -4, -38,  23,  16,   4, -63, -26, -50,  -3,   6,  21, -88,  26;
/M: SY='K';  M= -35, -16,  20,  24, -18, -38,   6, -21,  35,  12,  -9,   9, -31,  31,  -4, -14, -76,  -3, -32,  12;
/M: SY='Q';  M= -11,  15,  -5,  30,  -5, -37,  16,   3, -21, -10, -18,  28,  17,  30,  -4, -30, -12, -17,  30,   0;
/M: SY='D';  M= -18, -94,  28,  22,  19, -28,  -7, -13,  -7,  23, -16,   0, -44,  22,  -8,  -5, -34, -16, -20,  19;
/M: SY='C';  M=   6,  37, -31,  -5, -54, -74,   9, -28,  15,   9,  29,  18,  -7,   9,  17,  -3,  -9, -25, -89,  35;
/I:         E1=0; IE=-255; DE=-255;

» more

Post-processing [info]

PROMOTED_BY

PS51183

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.

Total number of hits	215 in 215 different sequences
Number of true positive hits	215 in 215 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	1
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	99.54 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	JmjC
Version [info]	5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

215 sequences

CBFA_DICDI  (O97101), ECM5_YEAST  (Q03214), ELF6_ARATH  (Q6BDA0),

GIS1_YEAST  (Q03833), HAIR_HUMAN  (O43593), HAIR_MOUSE  (Q61645), 
HAIR_RAT(P97609), HBAP1_BOVIN (Q58CU3), HBAP1_DANRE (Q6AXL5), 
HBAP1_HUMAN (Q96EW2), HBAP1_MOUSE (Q8BK58), HBAP1_RAT   (Q5BKC6), 
HIF1N_DANRE (P59723), HIF1N_HUMAN (Q9NWT6), HIF1N_MOUSE (Q8BLR9), 
JARD2_CHICK (Q5F363), JARD2_DANRE (Q1LVC2), JARD2_HUMAN (Q92833), 
JARD2_MOUSE (Q62315), JHD1_ASPFU  (Q4WHB7), JHD1_CAEBR  (Q60V67), 
JHD1_CAEEL  (Q95Q98), JHD1_CANAL  (Q5A847), JHD1_CANGA  (Q6FPL6), 
JHD1_CRYNB  (P0CO41), JHD1_CRYNJ  (P0CO40), JHD1_DEBHA  (Q6BXJ4), 
JHD1_DROME  (Q9VHH9), JHD1_EMENI  (Q5AW75), JHD1_EREGS  (Q75AL5), 
JHD1_KLULA  (Q6CIC9), JHD1_MYCMD  (Q4P5U1), JHD1_SCHPO  (O94603), 
JHD1_YARLI  (Q6C423), JHD1_YEAST  (P40034), JHD2C_HUMAN (Q15652), 
JHD2C_MOUSE (Q69ZK6), JHD2_YEAST  (P47156), JM703_ORYSJ (Q53WJ1), 
JM705_ORYSJ (Q5N712), JM706_ORYSJ (Q336N8), JMD6A_XENLA (Q6GND3), 
JMD6B_XENLA (Q7ZX37), JMJ13_ARATH (F4KIX0), JMJ14_ARATH (Q8GUI6), 
JMJ15_ARATH (O64752), JMJ16_ARATH (C0SUT9), JMJ17_ARATH (F4I240), 
JMJ18_ARATH (F4I6G4), JMJ19_ARATH (Q8L7T6), JMJ1_SCHPO  (O13977), 
JMJ20_ARATH (Q67ZB6), JMJ21_ARATH (Q9M9E8), JMJ22_ARATH (Q67XX3), 
JMJ24_ARATH (F4HZD1), JMJ25_ARATH (Q9SSE9), JMJ26_ARATH (C0SUU8), 
JMJ27_ARATH (Q8VYB9), JMJ28_ARATH (Q8H1S7), JMJ29_ARATH (C0SV12), 
JMJ2_SCHPO  (Q9US53), JMJ30_ARATH (Q8RWR1), JMJ31_ARATH (F4K2M8), 
JMJ31_CAEEL (Q95QK3), JMJ32_ARATH (Q0WVR4), JMJ3_SCHPO  (O94691), 
JMJ4_SCHPO  (O94606), JMJCA_DICDI (Q54FM1), JMJCB_DICDI (Q55FB9), 
JMJCC_DICDI (Q54LV7), JMJCD_DICDI (Q55DF5), JMJCE_DICDI (Q54CS7), 
JMJCF_DICDI (Q54FG7), JMJD4_CHICK (Q5ZHV5), JMJD4_DANRE (Q08BY5), 
JMJD4_DROME (Q9VJ97), JMJD4_HUMAN (Q9H9V9), JMJD4_MOUSE (Q8BFT6), 
JMJD6_BOVIN (Q58DS6), JMJD6_CAEBR (Q623U2), JMJD6_CAEEL (Q9GYI4), 
JMJD6_CHICK (Q5ZMK5), JMJD6_DANRE (Q6PFM0), JMJD6_DROME (Q9VD28), 
JMJD6_HUMAN (Q6NYC1), JMJD6_HYDVU (Q6Q4H1), JMJD6_MOUSE (Q9ERI5), 
JMJD6_PONAB (Q5R6G2), JMJD6_RAT   (Q6AYK2), JMJD7_HUMAN (P0C870), 
JMJD7_MOUSE (P0C872), JMJD8_HUMAN (Q96S16), JMJD8_MOUSE (Q3TA59), 
JMJD8_RAT   (Q6AY40), KD3AA_XENLA (Q6IRB8), KD3AB_XENLA (Q5HZN1), 
KD5BB_DANRE (Q6IQX0), KDM2A_HUMAN (Q9Y2K7), KDM2A_MOUSE (P59997), 
KDM2A_XENTR (Q5U263), KDM2B_HUMAN (Q8NHM5), KDM2B_MOUSE (Q6P1G2), 
KDM2B_XENLA (Q640I9), KDM3A_CHICK (Q5ZIX8), KDM3A_HUMAN (Q9Y4C1), 
KDM3A_MOUSE (Q6PCM1), KDM3A_RAT   (Q63679), KDM3B_HUMAN (Q7LBC6), 
KDM3B_MOUSE (Q6ZPY7), KDM4A_DROME (Q9V333), KDM4A_HUMAN (O75164), 
KDM4A_MOUSE (Q8BW72), KDM4A_PONAB (Q5RD88), KDM4B_DROME (Q9V6L0), 
KDM4B_HUMAN (O94953), KDM4B_MOUSE (Q91VY5), KDM4C_HUMAN (Q9H3R0), 
KDM4C_MOUSE (Q8VCD7), KDM4D_HUMAN (Q6B0I6), KDM4D_MOUSE (Q3U2K5), 
KDM4D_RAT   (A1A5Q5), KDM4E_HUMAN (B2RXH2), KDM4F_HUMAN (A0A1W2PPD8), 
KDM4_CAEEL  (Q9U297), KDM5A_HUMAN (P29375), KDM5A_MOUSE (Q3UXZ9), 
KDM5B_CHICK (Q5F3R2), KDM5B_HUMAN (Q9UGL1), KDM5B_MOUSE (Q80Y84), 
KDM5C_CANLF (Q38JA7), KDM5C_HUMAN (P41229), KDM5C_MOUSE (P41230), 
KDM5C_PIG   (A1YVX4), KDM5D_CANLF (Q30DN6), KDM5D_HUMAN (Q9BY66), 
KDM5D_MOUSE (Q62240), KDM5D_PANTR (Q5XUN4), KDM5_CAEBR  (Q61T02), 
KDM5_CAEEL  (Q23541), KDM5_DROME  (Q9VMJ7), KDM6A_HUMAN (O15550), 
KDM6A_MOUSE (O70546), KDM6B_HUMAN (O15054), KDM6B_MOUSE (Q5NCY0), 
KDM7A_DANRE (Q5RHD1), KDM7A_HUMAN (Q6ZMT4), KDM7A_MOUSE (Q3UWM4), 
KDM7A_XENTR (Q08D35), KDM7B_DANRE (P0CF52), KDM7_CAEEL  (Q9GYI0), 
KDM8_BOVIN  (Q1JP61), KDM8_DANRE  (A8E534), KDM8_HUMAN  (Q8N371), 
KDM8_MOUSE  (Q9CXT6), KDM8_RAT(Q497B8), KDM8_SALSA  (B5XF11), 
KDM8_XENTR  (B2GUS6), LID2_SCHPO  (Q9HDV4), MSC1_SCHPO  (Q9UT79), 
NO66_AEDAE  (Q16W06), NO66_BRAFL  (C3XRY1), NO66_BRUMA  (A8QFQ3), 
NO66_CAEBR  (A8XEA2), NO66_CAEEL  (O01658), NO66_CULQU  (B0WMG3), 
NO66_DICDI  (Q54K96), NO66_DROAN  (B3MSI4), NO66_DROER  (B3NU20), 
NO66_DROGR  (B4JMQ2), NO66_DROME  (Q7K4H4), NO66_DROMO  (B4L6Q5), 
NO66_DROPE  (B4GUZ2), NO66_DROPS  (B5DUH6), NO66_DROSE  (B4I100), 
NO66_DROSI  (B4R4H1), NO66_DROVI  (B4M7P8), NO66_DROWI  (B4NP88), 
NO66_DROYA  (B4Q068), PHF2_DANRE  (Q6P949), PHF2_DICLA  (E6ZGB4), 
PHF2_HUMAN  (O75151), PHF2_MOUSE  (Q9WTU0), PHF8_DANRE  (P0CH95), 
PHF8_HUMAN  (Q9UPP1), PHF8_MOUSE  (Q80TJ7), REF6_ARATH  (Q9STM3), 
RIOX1_BOVIN (A5PK74), RIOX1_CHICK (Q5ZMM1), RIOX1_DANRE (A3KP59), 
RIOX1_HUMAN (Q9H6W3), RIOX1_MOUSE (Q9JJF3), RIOX1_RAT   (D3ZU57), 
RIOX2_BOVIN (Q5EA24), RIOX2_HUMAN (Q8IUF8), RIOX2_MOUSE (Q8CD15), 
RIOX2_PONAB (Q5R673), RIOX2_RAT   (Q8CFC1), ROXA_ECOLI  (P27431), 
RPH1_YEAST  (P39956), SE14_ORYSJ  (Q10RP4), TYW4_ASPFU  (Q4WVD1), 
TYW4_ASPOR  (Q2U6D4), TYW4_EMENI  (Q5BH52), TYW4_GIBZE  (Q4IER0), 
TYW4_NEUCR  (Q9P3K9), TYW4_YARLI  (Q6C3P4), TYW5_CHICK  (E1C7T6), 
TYW5_DANRE  (Q08BV2), TYW5_HUMAN  (A2RUC4), TYW5_MOUSE  (A2RSX7), 
UTY_HUMAN   (O14607), UTY_MOUSE   (P79457), Y396_HAEIN  (P44683), 
YL887_MIMIV (Q5UQY3), YXBC_BACSU  (P46327)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

1 sequence

DPY21_CAEEL (Q9GRZ3)

PDB
[Detailed view]

691 PDB

1H2K; 1H2L; 1H2M; 1H2N; 1IZ3; 1MZE; 1MZF; 1VRB; 1YCI; 2CGN; 2CGO; 2GP3;
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