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PROSITE entry PS50850


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50850
Entry name [info] MFS
Accession [info] PS50850
Entry type [info] MATRIX
Date [info] 01-JUN-2003 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50850

Name and characterization of the entry

Description [info] Major facilitator superfamily (MFS) profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=393;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=388;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5937655; R2=0.0212681; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=14798.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=278; H_SCORE=14798; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=184; H_SCORE=14798; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-9; D=-50; I=-50; B1=-1000; E1=-1000; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 1'909 in 1'906 different sequences
Number of true positive hits 1'904 in 1'901 different sequences
Number of 'unknown' hits 1
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 190
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 99.79 %
Recall (true positives / (true positives + false negatives)) 90.93 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
1901 sequences

ABAF_ACIBT  (P0DPR5), ABAQ_ACIBA  (P0DPR4), ACDC_ASPCN  (A0A2I2F271), 
» more

UniProtKB/Swiss-Prot
False negative sequences
190 sequences

AMPG2_RICBR (Q1RHK8), AMPG2_RICCN (Q92GV3), AMPG2_RICFE (Q4UMU2), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
4 sequences

MDTD_SHIDS  (Q32EI1), MOT1_MERUN  (O35439), VACHT_MACFU (Q28487), 
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

BCH2_RHOCB  (P26171)

		
UniProtKB/Swiss-Prot
False positive sequences
4 sequences

AT221_ASPNC (A2QFJ9), AT222_ASPOR (Q2UD74), AT222_EMENI (Q5AVT9), 
» more

PDB
[Detailed view]
238 PDB

1PV6; 1PV7; 1PW4; 2CFP; 2CFQ; 2GFP; 2V8N; 2Y5Y; 3O7P; 3O7Q; 4GBY; 4GBZ;
» more