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PROSITE entry PS50180


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General information about the entry

Entry name [info] GAE
Accession [info] PS50180
Entry type [info] MATRIX
Date [info] 01-MAY-2003 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50180
Associated ProRule [info] PRU00093

Name and characterization of the entry

Description [info] Gamma-adaptin ear (GAE) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=116;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=111;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8907000; R2=0.0260890; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=7547.5498047; R2=9.2464361; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=311; H_SCORE=10423; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=177; H_SCORE=9184; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 21 in 21 different sequences
Number of true positive hits 21 in 21 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 84.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] GAE
Version [info] 7

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
21 sequences

AP1G1_ARATH (Q84K16), AP1G1_HUMAN (O43747), AP1G1_MOUSE (P22892), 
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UniProtKB/Swiss-Prot
False negative sequences
4 sequences

AP1G1_YEAST (Q12028), AP2A1_ARATH (Q8LPL6), AP2A2_ARATH (Q8LPK4), 
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PDB
[Detailed view]
18 PDB

1GYU; 1GYV; 1GYW; 1IU1; 1NA8; 1OM9; 1P4U; 2A7B; 2DWX; 2DWY; 2E9G; 2YMT;
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