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PROSITE entry PS50119


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50119
Entry name [info] ZF_BBOX
Accession [info] PS50119
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50119
Associated ProRule [info] PRU00024

Name and characterization of the entry

Description [info] Zinc finger B-box type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=46;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=42;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.2773000; R2=0.0142244; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1784.5047607; R2=3.9337540; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=508; H_SCORE=3783; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=368; H_SCORE=3232; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 331 in 280 different sequences
Number of true positive hits 331 in 280 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 34
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 90.68 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] ZN_FING
Feature description [info] B box-type
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
280 sequences

A33_PLEWA   (Q02084), BBX18_ARATH (Q9SJU5), BBX19_ARATH (C0SVM5), 
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UniProtKB/Swiss-Prot
False negative sequences
34 sequences

BBX32_ARATH (Q9LJB7), BSPRY_HUMAN (Q5W0U4), BSPRY_MOUSE (Q80YW5), 
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PDB
[Detailed view]
43 PDB

1FRE; 2CSV; 2D8U; 2DID; 2DIF; 2DJA; 2DQ5; 2EGM; 2FFW; 2JUN; 2MVW; 2YRG;
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