PROSITE logo

PROSITE entry PS50110


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50110
Entry name [info] RESPONSE_REGULATORY
Accession [info] PS50110
Entry type [info] MATRIX
Date [info] 01-JAN-2002 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50110
Associated ProRule [info] PRU00169

Name and characterization of the entry

Description [info] Response regulatory domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=115;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=110;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2297688; R2=0.0088634; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=13197.7197266; R2=11.0505791; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=934; H_SCORE=23519; N_SCORE=10.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=482; H_SCORE=18524; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-33; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 1'070 in 1'050 different sequences
Number of true positive hits 1'070 in 1'050 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 7
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.35 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 3
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] Sigrist_CJA
Feature key [info] DOMAIN
Feature description [info] Response regulatory
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
1050 sequences

ACTR_RHIME  (P0C5S3), ACTR_SINMW  (A6UEL7), AFSQ1_STRCO (Q04942), 
» more

UniProtKB/Swiss-Prot
False negative sequences
7 sequences

CHEB2_LEPIC (P62642), CHEB2_LEPIN (Q8F5D8), CHEB_BORBU  (Q45047), 
» more

PDB
[Detailed view]
241 PDB

1A04; 1A0O; 1A2O; 1AB5; 1AB6; 1B00; 1BDJ; 1C4W; 1CEY; 1CHN; 1CYE; 1D4Z;
» more