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PROSITE entry PS50022


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50022
Entry name [info] FA58C_3
Accession [info] PS50022
Entry type [info] MATRIX
Date [info] 01-MAY-2003 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00988
Associated ProRule [info] PRU00081

Name and characterization of the entry

Description [info] Coagulation factors 5/8 type C domain (FA58C) profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=150;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=150;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1392250; R2=0.0273076; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=233; N_SCORE=8.5000; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=160; N_SCORE=6.5000; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-50; I=-50; B1=-200; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 126 in 94 different sequences
Number of true positive hits 124 in 92 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 98.41 %
Recall (true positives / (true positives + false negatives)) 98.41 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] P_Bucher, N_Hulo
Feature key [info] DOMAIN
Feature description [info] F5/8 type C
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
92 sequences

ADAC_FLAPL  (P0DTR4), AEBP1_HUMAN (Q8IUX7), AEBP1_MOUSE (Q640N1), 
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UniProtKB/Swiss-Prot
False negative sequences
2 sequences

AFTD_MYCS2  (A0QPD4), HYBA2_BIFL2 (E8MGH9)

		
UniProtKB/Swiss-Prot
False positive sequences
2 sequences

OGA_CLOP1   (Q0TR53), OGA_CLOPE   (Q8XL08)

		
PDB
[Detailed view]
129 PDB

1CFG; 1CZS; 1CZT; 1CZV; 1D7P; 1EUT; 1EUU; 1FAC; 1GOF; 1GOG; 1GOH; 1IQD;
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