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PROSITE entry PS00761


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00761
Entry name [info] SPASE_I_3
Accession [info] PS00761
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00418

Name and characterization of the entry

Description [info] Signal peptidases I signature 3.
Pattern [info] 
[LIVMFYW](2)-{NLPA}-{T}-G-D-[NH]-{PIEW}-x(2)-[SND]-x(2)-[SG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 112 in 112 different sequences
Number of true positive hits 90 in 90 different sequences
Number of 'unknown' hits 0
Number of false positive hits 22 in 22 different sequences
Number of false negative sequences 61
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 80.36 %
Recall (true positives / (true positives + false negatives)) 59.60 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 90 sequences 

IMP1A_ARATH (Q6NLT8), IMP2L_BOVIN (Q2KI92), IMP2L_DANRE (Q6AZD4),
» more

UniProtKB/Swiss-Prot
False negative sequences		 61 sequences 

IMP1L_HUMAN (Q96LU5), IMP1L_MOUSE (Q9CQU8), IMP1L_XENTR (Q28I39),
» more

UniProtKB/Swiss-Prot
False positive sequences		 22 sequences 

ACSA_PASMU  (Q9CMW1), ADPRL_MIMIV (Q5UQP4), C508D_DICDI (Q1ZXA4),
» more

PDB
[Detailed view]		 12 PDB

1B12; 1KN9; 1T7D; 3IIQ; 3S04; 4WVG; 4WVH; 4WVI; 4WVJ; 6B88; 7P2P; 7P2Q