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PROSITE entry PS00560


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00560
Entry name [info] CARBOXYPEPT_SER_HIS
Accession [info] PS00560
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00122
Associated ProRule [info] PRU10075

Name and characterization of the entry

Description [info] Serine carboxypeptidases, histidine active site.
Pattern [info] 
[LIVF]-x(2)-[LIVSTA]-x-[IVPST]-x-[GSDNQL]-[SAGV]-[SG]-H-x-[IVAQ]-P-x(3)-
[PSA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 84 in 84 different sequences
Number of true positive hits 83 in 83 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 129
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 98.81 %
Recall (true positives / (true positives + false negatives)) 39.15 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] active_site at position 10
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 83 sequences 

ATG42_YEAST (P38109), CBP1_HORVU  (P07519), CBP1_ORYSJ  (P37890),
» more

UniProtKB/Swiss-Prot
False negative sequences		 129 sequences 

CBPYA_AJECG (C0NX46), CBPYA_AJECN (A6RGA0), CBPYA_AJEDR (C5GEU5),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

PEP1_ASPNG  (P55749)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			1 sequence
			


			
AZPB2_ASPTN (Q0CF73)


				
	

	

		PDB
[Detailed view]		
		
			20 PDB
			


			1AC5; 1BCR; 1BCS; 1CPY; 1GXS; 1IVY; 1WHS; 1WHT; 1WPX; 1YSC; 3SC2; 4AZ0; 
			
			

			» more