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PROSITE entry PS00488


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00488
Entry name [info] PAL_HISTIDASE
Accession [info] PS00488
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00424
Associated ProRule [info] PRU10122

Name and characterization of the entry

Description [info] Phenylalanine and histidine ammonia-lyases signature.
Pattern [info] 
[GS]-[STG]-[LIVM]-[STG]-[SAC]-S-G-[DH]-L-x-[PN]-L-[SA]-x(2,3)-[SAGVTL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 273 in 273 different sequences
Number of true positive hits 273 in 273 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.64 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 6
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 273 sequences 

CCTP1_TALIS (P9WEN6), CLZ10_COCLU (A0A345BJN1), HALL_DICDI  (Q556V9),
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

HUTH_RHORT  (Q2RUU3)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			4 sequences
			


			
PAL1_PHAVU  (P07218), PALY_AGABI  (Q92195), PALY_MALDO  (P35512), 

			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			41 PDB
			


			1B8F; 1EB4; 1GK2; 1GKJ; 1GKM; 1T6J; 1T6P; 1W27; 1Y2M; 2NYF; 2NYN; 2O6Y; 
			
			

			» more