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PROSITE entry PS00478


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00478
Entry name [info] LIM_DOMAIN_1
Accession [info] PS00478
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00382

Name and characterization of the entry

Description [info] LIM zinc-binding domain signature.
Pattern [info] 
C-x(2)-C-x(15,21)-[FYWHPCR]-H-x(2)-[CH]-x(2)-C-x(2)-C-x(3)-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 792 in 400 different sequences
Number of true positive hits 790 in 398 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 7
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.75 %
Recall (true positives / (true positives + false negatives)) 99.12 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 5
Site [info] zinc at position 1
Site [info] zinc at position 3
Site [info] zinc at position 6
Site [info] zinc at position 8
Site [info] zinc at position 10
Site [info] zinc at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 398 sequences 

ABLM1_HUMAN (O14639), ABLM1_MOUSE (Q8K4G5), ABLM2_HUMAN (Q6H8Q1),
» more

UniProtKB/Swiss-Prot
False negative sequences		 7 sequences 

ADCE_DICDI  (Q55GN8), HEL2_SCHPO  (Q76PD2), HEL2_YEAST  (Q05580),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

LASP1_PIG   (P80171)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
SIR7_DROME  (Q9VAQ1), YEMC_SCHPO  (O14033)


				
	

	

		PDB
[Detailed view]		
		
			71 PDB
			


			1A7I; 1B8T; 1CTL; 1CXX; 1G47; 1IBI; 1IML; 1J2O; 1M3V; 1NYP; 1QLI; 1RUT; 
			
			

			» more