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PROSITE entry PS00131


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00131
Entry name [info] CARBOXYPEPT_SER_SER
Accession [info] PS00131
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-FEB-2003 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00122
Associated ProRule [info] PRU10074

Name and characterization of the entry

Description [info] Serine carboxypeptidases, serine active site.
Pattern [info] 
[LIVM]-x-[GSTA]-E-S-Y-[AG]-[GS].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 172 in 172 different sequences
Number of true positive hits 164 in 164 different sequences
Number of 'unknown' hits 0
Number of false positive hits 8 in 8 different sequences
Number of false negative sequences 56
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 95.35 %
Recall (true positives / (true positives + false negatives)) 74.55 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 164 sequences 

ACUI_ASPA1  (A0A1L9WN42), ATG42_YEAST (P38109), CBP1_HORVU  (P07519),
» more

UniProtKB/Swiss-Prot
False negative sequences		 56 sequences 

DAP4_PSEMX  (Q6F3I7), HNLS_SORBI  (P52708), KEX1_AJECN  (A6QX86),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

CBPX_PEA(Q41005), PEP1_ASPNG  (P55749)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			8 sequences
			


			
CAPSD_TTVV9 (Q9DUC4), CO4A3_HUMAN (Q01955), COMB_STRPN  (P36498), 

			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			18 PDB
			


			1AC5; 1BCR; 1BCS; 1IVY; 1WHS; 1WHT; 1WPX; 1YSC; 3SC2; 4AZ0; 4AZ3; 4CI9; 
			
			

			» more