PROSITE entry PS00107

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00107
Entry name [info]	PROTEIN_KINASE_ATP
Accession [info]	PS00107
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-NOV-1995 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00100

Name and characterization of the entry

Description [info]	Protein kinases ATP-binding region signature.
Pattern [info]	[LIV]-G-{P}-G-{P}-[FYWMGSTNH]-[SGA]-{PW}-[LIVCAT]-{PD}-x-[GSTACLIVMFY]- x(5,18)-[LIVMFYWCSTAR]-[AIVP]-[LIVMFAGCKR]-K.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.

Total number of hits	3'461 in 3'437 different sequences
Number of true positive hits	3'274 in 3'250 different sequences
Number of 'unknown' hits	0
Number of false positive hits	187 in 187 different sequences
Number of false negative sequences	1'127
Number of 'partial' sequences	21

Precision (true positives / (true positives + false positives))	94.60 %
Recall (true positives / (true positives + false negatives))	74.39 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	2
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	3250 sequences 019R_FRG3G (Q6GZV6), 389L_IIV6 (Q91FD5), 7LESS_DROME (P13368), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	1127 sequences 044L_IIV3 (Q197B6), 7TMK2_DICDI (Q54U65), AAK1_BOVIN (F1MH24), » more
UniProtKB/Swiss-Prot 'Partial' sequences	21 sequences AAIP_WHEAT (Q02066), AAPK1_PIG (Q09136), ABL_CALVI (P11681), » more
UniProtKB/Swiss-Prot False positive sequences	187 sequences ABCC3_DICDI (Q54JR2), ACA7_ORYSJ (Q7XEK4), AKR1_SOYBN (C6TBN2), » more
PDB [Detailed view]	6479 PDB 1A06; 1A9U; 1AD5; 1AGW; 1APM; 1AQ1; 1ATP; 1B38; 1B39; 1B6C; 1BI7; 1BI8; » more