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PROSITE entry PS00027


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00027
Entry name [info] HOMEOBOX_1
Accession [info] PS00027
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00027

Name and characterization of the entry

Description [info] 'Homeobox' domain signature.
Pattern [info] 
[LIVMFYG]-[ASLVR]-x(2)-[LIVMSTACN]-x-[LIVM]-{Y}-x(2)-{L}-[LIV]-
[RKNQESTAIY]-[LIVFSTNKH]-W-[FYVC]-x-[NDQTAH]-x(5)-[RKNAIMW].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 1'374 in 1'368 different sequences
Number of true positive hits 1'362 in 1'356 different sequences
Number of 'unknown' hits 0
Number of false positive hits 12 in 12 different sequences
Number of false negative sequences 294
Number of 'partial' sequences 21
Precision (true positives / (true positives + false positives)) 99.13 %
Recall (true positives / (true positives + false negatives)) 82.25 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 2
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 1356 sequences 

ABDA_AEDAE  (P29552), ABDA_ANOGA  (O76762), ABDA_APIME  (P15856),
» more

UniProtKB/Swiss-Prot
False negative sequences		 294 sequences 

ADN1A_DANRE (F1QLG5), ADN2A_DANRE (A4QP16), ADNP2_HUMAN (Q6IQ32),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 21 sequences 

BCD_DROSU   (P55924), DLX1_RAT(Q64202), DLX2_ELECQ  (P87393),
» more

UniProtKB/Swiss-Prot
False positive sequences		 12 sequences 

ABCBB_MOUSE (Q9QY30), FKS1_CRYNH  (O93927), MDR2_CRIGR  (P21449),
» more

PDB
[Detailed view]		 165 PDB

1AHD; 1AKH; 1AU7; 1B72; 1B8I; 1BW5; 1CQT; 1DU0; 1DU6; 1E3O; 1F43; 1FJL;
» more