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PROSITE entry PS00012


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00012
Entry name [info] PHOSPHOPANTETHEINE
Accession [info] PS00012
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00012

Name and characterization of the entry

Description [info] Phosphopantetheine attachment site.
Pattern [info] 
[DEQGSTALMKRH]-[LIVMFYSTAC]-[GNQ]-[LIVMFYAG]-[DNEKHS]-S-[LIVMST]-{PCFY}-
[STAGCPQLIVMF]-[LIVMATN]-[DENQGTAKRHLM]-[LIVMWSTA]-[LIVGSTACR]-{LPIY}-
{VY}-[LIVMFA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 1'605 in 1'359 different sequences
Number of true positive hits 1'208 in 962 different sequences
Number of 'unknown' hits 2 in 2 different sequences
Number of false positive hits 395 in 395 different sequences
Number of false negative sequences 321
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 75.36 %
Recall (true positives / (true positives + false negatives)) 79.01 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 9
Site [info] phosphopantetheine at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 962 sequences 

5MOAS_ASPTN (Q0CRQ5), ACDB_ASPCN  (A0A2I2F262), ACE1_PYRO7  (G4MVZ2),
» more

UniProtKB/Swiss-Prot
False negative sequences		 321 sequences 

AACP1_BRADU (Q89VT6), AACP2_BRADU (Q89GR1), AACP_AGRFC  (A9CHM9),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 5 sequences 

ACP_ACICA   (P80916), ACP_ALCFA   (P80917), ACP_ERYLO   (P80919),
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 2 sequences 

MEIOC_HUMAN (A2RUB1), MEIOC_MOUSE (A2AG06)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			395 sequences
			


			
172L_IIV6   (O55764), AB21G_ARATH (Q7XA72), AB26G_ARATH (Q9LK50), 

			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			276 PDB
			


			1ACP; 1AF8; 1DNY; 1FH1; 1HY8; 1L0H; 1L0I; 1NQ4; 1T8K; 1X3O; 2AF8; 2AVA; 
			
			

			» more