ENZYME entry: EC 3.4.23.46
Accepted Name | ||||||
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memapsin 2 | ||||||
Alternative Name(s) | ||||||
BACE1 | ||||||
beta-secretase | ||||||
beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 | ||||||
beta-site APP-cleaving enzyme 1 | ||||||
membrane-associated aspartic protease 2 | ||||||
Reaction catalysed | ||||||
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein | ||||||
Comment(s) | ||||||
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Cross-references | ||||||
BRENDA | 3.4.23.46 | |||||
EC2PDB | 3.4.23.46 | |||||
ExplorEnz | 3.4.23.46 | |||||
PRIAM enzyme-specific profiles | 3.4.23.46 | |||||
KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.46 | |||||
IUBMB Enzyme Nomenclature | 3.4.23.46 | |||||
IntEnz | 3.4.23.46 | |||||
MEDLINE | Find literature relating to 3.4.23.46 | |||||
MetaCyc | 3.4.23.46 | |||||
Rhea expert-curated reactions | 3.4.23.46 | |||||
UniProtKB/Swiss-Prot |
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